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At planets that possess strong dipole magnetic fields, charged particles can be squeezed along magnetic fields helping to deflect the solar wind flow about the planet. Here, the authors show this effect occurring in the ionosphere of Mars, a planet without a strong dipole magnetic field.

MRI scanners depend on large, noisy magnetic gradient coils that limit their accessibility worldwide. Here, the authors show that radiofrequency field gradients can perform frequency encoding with simultaneous transmit and receive, producing images matching conventional quality and enabling smaller, lower-cost MRI systems.

Understanding collective behaviour is an important aspect of managing the pandemic response. Here the authors show in a large global study that participants that reported identifying more strongly with their nation reported greater engagement in public health behaviours and support for public health policies in the context of the pandemic.

Jayaram et al. assessed the performance of the combination of circulating tumor DNA and serum prostate-specific antigen for dynamic monitoring of metastatic prostate cancer at first-line treatment in this prospective observational clinical trial.

A drawing-like task designed to study compositional generalization identifies a specific neural population in the ventral premotor cortex in primates that encodes action symbols.

Electron-beam control enables deterministic placement of tens of thousands of atomic defects in three-dimensional crystals, creating stable, programmable artificial matter for scalable quantum and nanoscale technologies.

Natural genetic variation of photosynthesis is an underexplored resource for plant genetic improvement. Here, the authors find allelic variations of YS1 affect Arabidopsis photosynthesis acclimation using genome-wide association study, reverse genetics, and quantitative complementation approaches.

Disentangling the exotic phases that can emerge at the surfaces of strongly correlated materials from the bulk is experimentally difficult. Here, Jain, Diao, Ong, Rusydi, and coauthors succeed in doing so, using grazing incident-angle dependent resonant X-ray scattering to find an emergent surface magnetic ordering and surface electronic dipole layers in the two-dimensional film of La2CuO4

This study identifies distinct transposable element subfamilies as genetic determinants of stemness properties in normal and leukemic stem populations with clinical implications for patients with acute myeloid leukemia.

Genome-wide analyses identify genetic loci and plasma proteins associated with polycystic ovary syndrome (PCOS). This study highlights the hormonal and metabolic foundations of the disease and explores the impact of polygenic risk for PCOS in both sexes.

In this Journal Club, Mark Anthony revisits a paper showing how an invasive plant disrupts mycorrhizal symbioses, reducing native tree seedling growth and reshaping forest communities.

How the brain supports speaking and listening during conversation of its natural form remains poorly understood. Here, by combining intracranial EEG recordings with Natural Language Processing, the authors show broadly distributed frontotemporal neural signals that encode context-dependent linguistic information during both speaking and listening..

Compiling data on floral introductions and European colonial history of regions worldwide, the authors find that compositional similarity of floras is higher than expected among regions once occupied by the same empire and similarity increases with the length of time the region was occupied by that empire.

Liu, Gad et al. develop an approach to purify the endoplasmic reticulum and integrate genetic, structural, molecular and cell biological analyses to identify SLC33A1 as an endoplasmic reticulum oxidized glutathione (GSSG) exporter in mammalian cells.

A national classification system of wetland hydrologic connectivity to streams, which could be applied globally, demonstrates and advances current understanding of how wetland connectivity affects surface water quality.

The authors use data on the entire Finnish population to develop a machine learning model for predicting COVID-19 vaccination uptake. Important predictors are proxies of socio-economic status, and those at high risk for COVID-19 consequences are less likely to get vaccinated.

Floquet engineering is emerging as a tool to control quantum materials. Here it is applied using non-resonant optical fields to coherently dress Hubbard excitons in Sr₂CuO₃, driving wavefunction rotations between bright and dark states.

HST and JWST observations of four nearby galaxies show that massive young star clusters disperse their natal gas faster than low-mass clusters, with key implications for star formation, stellar feedback and planet formation models.

Inducible base editors enhance cancer genomic screens in vivo.

Tailoring relativistic laser–plasma interactions on femtosecond timescales unlocks a direct route to extreme field generation using a coherent harmonic focus.

JWST observations of both the dayside and nightside of a hot exoplanet show that horizontal winds transport chemical species faster than the time they need to react chemically, which drives the nightside atmosphere out of chemical equilibrium.

Genomic epidemiology of 1,029 Streptococcus pyogenes emm1 and emm12 genome sequences collected between 1993 and 2024 in China reveals dominance of distinct lineages with mobile genetic element-encoded antibiotic resistance and virulence factor genes.

Gravitational-wave data reveal evidence for the pair-instability mass gap and a population of high-mass black hole mergers formed in star clusters. The measurement also constrains the nuclear reaction that regulates carbon–oxygen production in massive stars.

Higher-order interactions are shown to contribute to the decrease in species diversity from low to high latitudes in global forests, potentially explaining why this intricate phenomenon cannot be adequately explained by pairwise interactions alone.

Genetic analyses in more than 15,000 individuals from across the Americas, including individuals with autism and family members, define the genetic landscape of autism in Latin American populations and identify significant overlap with other ancestries.

Khurana et al. share their perspective on healthcare system preparedness in sub-Saharan Africa in light of the recent increase in ischemic heart disease burden, highlighting areas that require intervention to improve the management of this noncommunicable condition in the region.

Pelagic Sargassum blooms have expanded over time across the Great Atlantic Sargassum Belt. A nonlinear model indicates that winds and mixing drove growth in early years, while internal nutrient recycling now controls variability and supports forecasting.

In this individual participant data meta-analysis, and across 321,345 smartphone-ratings of affective well-being and nearly 1 million hours of physical activity measurement, Rehder et al. clarify the nature and extent of activity–well-being relations and document their relevance in humans’ everyday life.

Heterobilayers of transition metal dichalcogenides host moiré superlattices that give rise to strong electron interactions. Here, the authors study the photoluminescence from interlayer excitons in a WS₂/WSe₂ heterobilayer to reveal the onset of various correlated insulating states.

The TRACS algorithm tracks bacteria, viruses and parasites in metagenomic or population sequencing data, detecting microbial transmission even when multiple strains coexist within a host.

An electrochromic in-sensor computing architecture enables adaptive, pixel-level spectral compression before readout, reducing data transmission and supporting energy-efficient intelligent vision for edge-computing systems.

Agonistic antibodies initiate signalling by the receptors they target, mimicking the activities of native ligands. This Review discusses the clinical successes and failures of agonistic antibodies and explains how recent mechanistic insights should broaden the scope and improve the safety and efficacy of immunotherapies based on these agents.

Assessment of how 16 taxonomic groups in a lowland tropical forest resist and recover from anthropogenic disturbance shows the potential of protecting naturally regenerating secondary forests to reverse biodiversity losses.

Gram-negative bacteria use diverse virulence factors to infect eukaryotic cells. Here, the authors perform structure-function analyses on the S. negevensis deSUMOylase SnCE1 and provide mechanistic insights how lysine acetylation reprograms virulence adjusting it to the host cells’ metabolic state.

Many glomerular diseases have a genetic basis; however, not all identified variants are pathogenic. This Expert Recommendation from the Clinical Genome Resource (ClinGen) Glomerulopathy Gene Curation Expert Panel describes the outcomes of gene curation efforts to evaluate the evidence underlying asserted gene–disease relationships for 56 genes that have putatively been linked to glomerular diseases.

Reanalysis of radiometric data from Cassini indicates that Titan does not contain a subsurface ocean, as strong tidal dissipation observed in its gravity field is not consistent with the presence of a liquid layer.

Bacteria adjust their metabolism to the cellular energy state. Here, authors identify a layer of regulation of AMP-forming acetyl-CoA synthetase AcsA activity by AcuB acting as energy sensor inhibiting the AcsA deacetylase AcuC in presence of AMP.

By studying 23 neurodevelopmental disorder genes across model systems and brain cell types, the authors uncovered shared downstream effects that converge on synaptic biology, epigenetic regulation and mitochondrial function.

Decreased brain volumes and increased NfL levels can be observed earlier than disease diagnosis in short-tandem-repeat-associated neurological diseases.

The authors demonstrate a method for the manipulation of the motion of chiral nanoparticles, which involves utilising circularly polarised light in an ultrathin optical fibre. The evanescent field of this fibre can both trap and propel particles near the fibre surface, with the direction of the particle motion depending on the circular polarisation state of the light.

The authors have applied an eight-tissue rat multi-omic dataset to analyze the gene regulatory landscape of endurance exercise training, identifying tissue-specific regulatory patterns involved in muscle function, metabolism and immune response.

An element-isotope coupled inverse model quantifies marine Mg removal rates via silicate and dolomite formation, linking Phanerozoic seawater Mg/Ca oscillations to supercontinent-driven tectonic and climatic changes.

Salladay-Perez and colleagues explore senescence induction in human and mouse macrophages using multiomic profiling. They characterize a p21⁺TREM2⁺ senescent macrophage population, which they functionally implicate in inflammaging and liver disease.

Robustness checks and reproduction of analyses with existing and updated data based on 110 articles in economics and political science journals with data and code-sharing requirements found high levels of robustness and reproducibility and determined that robustness was not dependent on author characteristics or data availability.

Hutchinson-Gilford Progeria Syndrome is characterized by premature aging with cardiovascular disease being the main cause of death. Here the authors show that inhibition of the NAT10 enzyme enhances cardiac function and fitness, and reduces age-related phenotypes in a mouse model of premature aging.