Microbial biosynthesis is a promising alternative to plant extraction to obtain post-modified flavonoids, but current de novo biosynthesis is limited to milligrams per litre. Now the production of plant-derived medicinal flavonoid monoglycosides and diglycosides is reported from simple carbon sources in an unconventional yeast at over 26 g l−1.
- Zhilan Qian
- Haishuang Yu
- Menghao Cai