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Showing 1–2 of 2 results
Advanced filters: Author: Nancy Varice Clear advanced filters

  • A combined sequencing technique assesses 18 patients with high-grade serous ovarian cancer over a multi-year period from diagnosis to recurrence and shows drug resistance typically arises from selective expansion of one or a few clones present at diagnosis.

    • Marc J. Williams
    • Ignacio Vázquez-García
    • Sohrab P. Shah
    ResearchOpen Access
    Nature
    Volume: 647, P: 757-765

  • A single-cell sequencing study using more than 30,000 tumour genomes from human ovarian cancers shows that whole-genome doubling is an ongoing mutational process that drives tumour evolution and disrupts immunity.

    • Andrew McPherson
    • Ignacio Vázquez-García
    • Sohrab P. Shah
    ResearchOpen Access
    Nature
    Volume: 644, P: 1078-1087