Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–8 of 8 results
Advanced filters: Author: Nicolas Ruffin Clear advanced filters

  • A preprint by Martinez-Riano et al. evaluates the dynamics of antigen retention by follicular dendritic cells (FDCs) in germinal centres, showing that immune complexes accumulate in the centre of the FDC network.

    • Nicolas Ruffin
    • Ester Gea-Mallorquí
    Research Highlights
    Nature Reviews Immunology
    Volume: 22, P: 715

  • A preprint by Jerby-Arnon et al. uses a novel algorithm for scRNAseq data to describe a pan-cancer programme for dysfunctional tumour-infiltrating lymphocytes that predicts response to immune checkpoint blockade therapy.

    • Nicolas Ruffin
    • Andre Ortlieb Guerreiro-Cacais
    Research Highlights
    Nature Reviews Immunology
    Volume: 22, P: 74

  • Artificial intelligence is rapidly transforming structural biology and accelerating access to protein structures, yet many Africa-based scientists still lack infrastructure, training opportunities, and sustained mentorship to fully benefit. Here, we describe BioStruct-Africa’s community-driven framework integrating AlphaFold, experimental structural biology, and computational drug design to train 1000 scientists over the next decade.

    • Justice O. Amofa
    • Juergen George
    • Emmanuel Nji
    Comments & OpinionOpen Access
    Communications Biology
    Volume: 9, P: 1-6

  • Without addressing the lack of research infrastructure, funding, and supportive science policies, structural biology capacity-building efforts in Africa will continue to be hindered by the persistent challenge of brain drain.

    • Emmanuel Nji
    • Katharina C. Cramer
    • Safiétou Sankhe
    Comments & OpinionOpen Access
    Nature Communications
    Volume: 16, P: 1-2

  • Structural biology is crucial in understanding disease mechanisms and in driving drug and vaccine development—applications that are particularly relevant to Africa’s challenges—yet Africa faces significant barriers to advancing structural biology. Here, the authors outline a recent capacity building workshop run by BioStruct-Africa, focused on training of artificial intelligence tools such as AlphaFold, designed to foster a highly skilled community of structural biologists in Africa.

    • Safiétou Sankhe
    • Fatoumata G. Fofana
    • Emmanuel Nji
    Comments & OpinionOpen Access
    Communications Chemistry
    Volume: 8, P: 1-10