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Engineering the perovskite–electrical contact interface with sodium heptafluorobutyrate reduces interfacial defects and improves charge transport in perovskite solar cells. Functionalized devices deliver a certified power conversion efficiency of 26.96%, which is fully retained after 1,200 h of continuous operation under 1-sun illumination.

The BioDIGS project is a nationwide initiative involving students, researchers and educators across more than 40 research and teaching institutions. Participants lead sample collection, computational analysis and results interpretation to understand the relationships between the soil microbiome, environment and health.

The morphology control of metal halide perovskite crystalline films is of importance to enable high-performance solar cells. Here, Heet al. use a meniscus-assisted solution-based method to print microsized perovskite grains at 60 °C, which results in high optoelectronic device efficiency of 20%.

Early detection of signs of heart failure can allow fast therapeutic intervention, potentially improving a patient's prognosis and avoiding unnecessary hospitalizations. Implantable monitoring devices have been suggested as useful tools in detecting early changes in cardiac parameters, but clinical trials aimed at studying their efficacy and safety have unique problems. In this Review, Abraham et al. identify the major hurdles in trials of implantable monitoring devices, and discuss the approaches used to overcome the challenges arising during trial design.

Metal halide perovskites are promising for solar energy harvesting, but currently prone to a large hysteresis and current instability. Here, Xu et al. show improvements in a hybrid material in which the fullerene is distributed at perovskite grain boundaries and thus passivates defects effectively.

When light hits organic semiconductors, bound charge pairs, called excitons, are usually produced. Here, the authors show that in the best performing organic solar material to date, free charges, rather than excitons, are directly created by light.

Addressing nutrition and climate resilience together requires transdisciplinary participatory action research with clear impact pathways for systems change that starts from the ground up. The concept of ‘crops that nourish’ is proposed here to offer a new mode of pursuing agricultural development. It involves iterative co-creation between farmers and researchers that prioritizes local needs and agency, human health, resilience and sustainability through a focus on opportunity crops.

Viral pathogen load in cancer genomes is estimated through analysis of sequencing data from 2,656 tumors across 35 cancer types using multiple pathogen-detection pipelines, identifying viruses in 382 genomic and 68 transcriptome datasets.

Salt passivation of perovskite often results in formation of 2D perovskite layers, which impaired charge transport behaviour. Here, the authors study the energy barrier of 2D perovskite formation upon passivation by different iodide salt, and provide insight how to manipulate this to maximise device performance.

JWST reveals the chemistry of the disk of a young star in the Orion nebula, showing that it has water and CO in its inner regions that are shielded from UV radiation, whereas UV-processed molecules such as CH₃⁺ and PAHs are detected in surface layers.

Defects in perovskite materials are detrimental to their carrier dynamics and structural stability. Here, the authors incorporate 6H polytype perovskite into bulk to reduce defects and improve structural integrity, realizing efficient solar cells and modules with long-term stability.

Efficient and stable perovskite solar cells with simple active layers are desirable for manufacturing, yet formation of a two-dimensional component in the perovskite film compromises the performance. Here, the authors report low temperature fabrication of highly efficient and stable inverted solar cells by adding a fluorinated lead salt.

As silicon solar cells are reaching their optimal efficiencies, below 30%, multi-junctions are being developed to increase the electrical power output over the same area. Here, Cariou et al. use wafer-bonding to fabricate two-terminal silicon III–V tandem cells that reach efficiencies above 33%.

A dye-sensitized solar cell that has been designed for efficient operation under indoor lighting could offer a convenient means for powering the Internet of Things.

Indigenous peoples are disproportionally affected by poor kidney health outcomes globally. Here, a group of Indigenous and non-Indigenous authors provide a global overview of kidney health among Indigenous populations across different regions and its key determinants, including structural factors, and make actionable policy recommendations for addressing these health inequities.

A consensus cell type atlas for the fly brain provides both an intellectual framework and open-source toolchains for brain-scale comparative connectomics.

The incorporation of electron transport layers based on single-crystalline TiO₂ rhombohedral nanoparticles enables the realization of stable and efficient large-area perovskite solar cell modules.

Three electron microscopy datasets are combined to provide a complete connectomic description of the neural circuitry that makes up the neck connective in Drosophila, including the descending neurons, ascending neurons and sensory ascending neurons.

Electrochemical doping is assumed to be limited by ion motion due to large mass in mixed ionic-electronic conductors. Here, the authors reveal in a typical polythiophene that electrochemical doping speeds are limited by poor hole transport at low doping levels, leading to much slower switching speeds than expected.

How cell-cell contact is sensed by Hippo pathway is poorly understood. Here, the authors show that KIRREL1 functions as a feedback regulator of the mammalian Hippo pathway by sensing cell-cell interaction and recruiting SAV1 to cell-cell contacts.

Liet al. study degradation in organic photovoltaics from a morphological perspective. They find that donor and acceptor phases undergo excessive demixing via spinodal decomposition resulting in a reduction of charge generation. Demixing is due to the inherently low miscibility of both materials.

Nanomaterials provide a route to efficient solid-state conversion between thermal and electrical energy. Here, the authors demonstrate that a combination of metal and semiconductor colloidal nanocrystals can produce thermoelectric nanocomposites with high performance.

The functions of the highly reduced mitochondria (mitosomes) of microsporidians are not well-characterized. Here, the authors show that theTrachipleistophora hominismitosome is the site of iron–sulfur cluster assembly and that its retention is likely linked to its role in cytosolic and nuclear iron–sulfur protein maturation.

The lesbian, gay, bisexual, transgender, queer, intersex and asexual (LGBTQIA+) community navigates a complex social landscape marked by strides in acceptance alongside enduring discrimination. Allies — individuals outside of the LGBTQIA+ spectrum who support and advocate for this community — are paramount, with allyship playing a critical part in influencing the health and well-being of LGBTQIA+ individuals.

The ‘on’ and ‘off’ states of the photoswitchable protein Dronpa have been characterized, but the interconversion process remains poorly understood. Here the authors perform time-resolved ultrafast infrared measurements to follow both the structural changes and proton transfer events that occur during conversion.

High-resolution structure analysis and directed mutagenesis experiments may at last be brought into step by the use of functional group analogues that alter individual atoms

To harness the potential of microbiome science across the broad range of relevant disciplines, new approaches to data infrastructure and transdisciplinary collaboration are necessary. The National Microbiome Data Collaborative is a new initiative to support microbiome data exploration and discovery through a collaborative, integrative data science ecosystem.

In this Viewpoint article,Nature Reviews Immunologyinvites five experts to share their thoughts on the contributions made by Élie Metchnikoff to the fields of phagocytosis, macrophage biology, leukocyte migration, the microbiota and intravital imaging.

Expert tips for acquirers and acquirees to get through a difficult post-merger integration.

The Pope has made a strong call for action on climate change, but it fails to address the complex linkages between sustainable development and demographic growth.

FlyWire presents a neuronal wiring diagram of the whole fly brain with annotations for cell types, classes, nerves, hemilineages and predicted neurotransmitters, with data products and an open ecosystem to facilitate exploration and browsing.

Joint analysis of new and previously published sequencing data for primary and metastatic prostate cancers identifies new candidate driver mutations and provides insights into disease progression and potential drug targets.

Here we show how PFL2 and PFL3 neurons in the Drosophila brain compare a representation of direction with internal spatial goals, both anchored in world-centric coordinates, and produce body-centric steering commands that act to correct deviations from the goal direction. 

Regulators will soon grapple with how to safely administer powerful psychedelics for treating depression and post-traumatic stress disorder.

A temperature-dependent kinetic study of ground-state proton transfer in the green fluorescent protein highlights the role of ‘deep tunnelling’ in proton wires. A potential mechanism for directional proton transport is proposed, where high-pK_a amino acid residues act as ‘tunnel diodes’ and as stabilizing elements within protein water wires.

Biodiversity conservation is critical for promoting ecosystem services and human well-being, but current conservation efforts fail to protect most high priority zones. A mix of land-sparing and land-sharing is needed to safeguard critical ecosystems in India and across the Global South.

Making large datasets findable, accessible, interoperable and reusable could accelerate technology development. Now, Jacobsson et al. present an approach to build an open-access database and analysis tool for perovskite solar cells.

Homo luzonensis, a new species of Homo from the Callao Cave in the Philippines from the Late Pleistocene epoch, is described.

The authors propose a framework to be followed during preclinical investigation of nanomedicines to increase their translatability potential.

Current narrow views of what constitutes evidence have left blind spots in food system decision-making. Yet, alternative ways of facilitating the production and exchange of transdisciplinary knowledge enable key lessons for more equitable and informed policy processes.