Nature Search

Potential Alzheimer’s early biomarkers in a transgenic rat model and benefits of diazoxide/dibenzoylmethane co-treatment on spatial memory and AD-pathology

Charles H. Wallace
Giovanni Oliveros
Maria Figueiredo-Pereira
ResearchOpen Access14 Feb 2024
Scientific Reports

Volume: 14, P: 1-13
Integrated single-cell atlas of human atherosclerotic plaques

Atherosclerosis is the major driver of mortality worldwide and recent studies provide first insights at single cell resolution. Here, the authors show that integrating all available studies enables coherent automatic cell type annotation, optimal experimental design and bulk deconvolution.

Korbinian Traeuble
Matthias Munz
Matthias Heinig
ResearchOpen Access10 Sept 2025
Nature Communications

Volume: 16, P: 1-16
Formation of droplet interface bilayers in a Teflon tube

Edmond Walsh
Alexander Feuerborn
Peter R. Cook
ResearchOpen Access29 Sept 2016
Scientific Reports

Volume: 6, P: 1-9
Orbital forcing of Cretaceous river discharge in tropical Africa and ocean response

Britta Beckmann
Sascha Flögel
Thomas Wagner
Research08 Sept 2005
Nature

Volume: 437, P: 241-244
Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor

Mitochondrial dysfunction in dopaminergic neurons is a pathological hallmark of Parkinson’s disease. Here, the authors find a conserved mechanism by which a single transcription factor controls mitochondrial health in dopaminergic neurons during the aging process.

Federico Miozzo
Eva P. Valencia-Alarcón
Emi Nagoshi
ResearchOpen Access17 Mar 2022
Nature Communications

Volume: 13, P: 1-18
Remodeling of lipid-foam prototissues by network-wide tension fluctuations induced by active particles

Constructing synthetic prototissues is a challenge in bottom-up synthetic biology. Here, the authors introduce a “lipid foam” tissue mimetic and demonstrate network-wide tension fluctuations upon compartmental encapsulation of actively swimming bacteria.

Andre A. Gu
Mehmet Can Uçar
Jan Steinkühler
ResearchOpen Access27 Feb 2025
Nature Communications

Volume: 16, P: 1-10
MHC class l/β₂-microglobulin complexes associate with TAP transporters before peptide binding

Bodo Ortmann
Matthew J. Androlewicz
Peter Cresswell
Research28 Apr 1994
Nature

Volume: 368, P: 864-867
Voltage-gated sodium channels in excitable cells as drug targets

The family of voltage-gated sodium channels (Na_Vs) are key mediators of electrical signals in excitable cells. In their broad Review, Waxman and colleagues discuss the potential to target Na_Vs in neurons, cardiac and skeletal muscle cells for the treatment of various neurological and muscular disorders.

Matthew Alsaloum
Sulayman D. Dib-Hajj
Stephen G. Waxman
Reviews03 Feb 2025
Nature Reviews Drug Discovery

Volume: 24, P: 358-378
Genetic refinement of the hereditary neuralgic amyotrophy (HNA) locus at chromosome 17q25

Jan Meuleman
Gregor Kuhlenbäumer
Vincent Timmerman
Research08 Dec 1999
European Journal of Human Genetics

Volume: 7, P: 920-927
Persistent serum protein signatures define an inflammatory subcategory of long COVID

Long COVID or post-acute sequelae of SARS-CoV-2 is defined by persisting chronic symptoms following acute SARS-CoV-2 infection but represent an aetiologically diverse group of disorders. Here authors identify molecularly distinct subtypes, including a form with persistent inflammation, via longitudinal analysis of serum proteome.

Aarthi Talla
Suhas V. Vasaikar
Troy R. Torgerson
ResearchOpen Access09 Jun 2023
Nature Communications

Volume: 14, P: 1-16
Homozygosity mapping of Hallervorden–Spatz syndrome to chromosome 20p12.3–p13

Todd D. Taylor
Michael Litt
Susan J. Hayflick
Research01 Dec 1996
Nature Genetics

Volume: 14, P: 479-481
Mutation and deletion of the pseudoautosomal gene SHOX cause Leri-Weill dyschondrosteosis

Deborah J. Shears
Humberto J. Vassal
Robin M. Winter
Research01 May 1998
Nature Genetics

Volume: 19, P: 70-73
Diamond-Blackfan anaemia: genetic homogeneity for a gene on chromosome 19q13 restricted to 1.8 Mb

Peter Gustavsson
Thiébaut-Noel Willig
Niklas Dahl
Research01 Aug 1997
Nature Genetics

Volume: 16, P: 368-371
A susceptibility locus for Parkinson's disease maps to chromosome 2p13

Thomas Gasser
Bertram Müller-Myhsok
Rolf D. Horstmann
Research01 Mar 1998
Nature Genetics

Volume: 18, P: 262-265
Genetic and environmental influences interact with age and sex in shaping the human methylome

Differential impact of genetic and environmental influences on DNA methylation may result in sex- and age-related physiological variation and disease susceptibility. By analysing DNA methylome of 2,603 individuals from twin families, here, the authors establish a catalogue of between-individual variation in DNA methylation.

Jenny van Dongen
Michel G. Nivard
Dorret I. Boomsma
ResearchOpen Access07 Apr 2016
Nature Communications

Volume: 7, P: 1-13
X-linked recessive inheritance of radial ray deficiencies in a family with four affected males

Robert-Jan H Galjaard
Naci Kostakoglu
Peter Heutink
Research14 Sept 2001
European Journal of Human Genetics

Volume: 9, P: 653-658
Germany contemplates new biotech tax scheme

Peter Mitchell
News01 Jun 2003
Nature Biotechnology

Volume: 21, P: 587-588
Positional cloning of the Fanconi anaemia group A gene

Sinoula Apostolou
Scott A. Whitmore
Robert K. Moyzis
Research01 Nov 1996
Nature Genetics

Volume: 14, P: 324-328
Unstable insertion in the 5′ flanking region of the cystatin B gene is the most common mutation in progressive myoclonus epilepsy type 1, EPM1

Ronald G. Lafreniére
Daniel L. Rochefort
Guy A. Rouleau
Research01 Mar 1997
Nature Genetics

Volume: 15, P: 298-302
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

Analyses of expression profiles from whole blood of 31,684 individuals identify cis-expression quantitative trait loci (eQTL) effects for 88% of genes and trans-eQTL effects for 37% of trait-associated variants.

Urmo Võsa
Annique Claringbould
Lude Franke
Research02 Sept 2021
Nature Genetics

Volume: 53, P: 1300-1310
Author Correction: ATP hydrolysis by yeast Hsp104 determines protein aggregate dissolution and size in vivo

Udhayabhaskar Sathyanarayanan
Marina Musa
Anita Krisko
Amendments and CorrectionsOpen Access14 Dec 2020
Nature Communications

Volume: 11, P: 1
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Felicity Liew
Claudia Efstathiou
J. Eunice Zhang
ResearchOpen Access08 Apr 2024
Nature Immunology

Volume: 25, P: 607-621
Sensitivity of South American tropical forests to an extreme climate anomaly

The authors analyse tree responses to an extreme heat and drought event across South America to understand long-term climate resistance. While no more sensitive to this than previous lesser events, forests in drier climates showed the greatest impacts and thus vulnerability to climate extremes.

Amy C. Bennett
Thaiane Rodrigues de Sousa
Oliver L. Phillips
ResearchOpen Access04 Sept 2023
Nature Climate Change

Volume: 13, P: 967-974
A de novo gain-of-function mutation in SCN11A causes loss of pain perception

Ingo Kurth and colleagues show that a specific de novo missense mutation in SCN11A results in an inability to experience pain. They further show that mutant channels display higher activity at resting voltages, causing sustained depolarization of pain receptors, impaired generation of action potentials and aberrant synaptic transmission.

Enrico Leipold
Lutz Liebmann
Ingo Kurth
Research15 Sept 2013
Nature Genetics

Volume: 45, P: 1399-1404
ATP hydrolysis by yeast Hsp104 determines protein aggregate dissolution and size in vivo

The sequestration of misfolded protein into insoluble aggregates occurs under conditions of proteotoxic stress. Here the authors observe that a reduction in cellular ATP promotes protein sequestration into two separate compartments: Q-bodies and stress granules; and identify Hsp104 as a critical ATP-consuming process that determines those compartments abundance and size.

Udhayabhaskar Sathyanarayanan
Marina Musa
Anita Krisko
ResearchOpen Access16 Oct 2020
Nature Communications

Volume: 11, P: 1-17
Addressing the role of eHealth literacy in shaping popular attitudes towards post-COVID-19 vaccination among Chinese adults

Wen Jiao
Peter Johannes Schulz
Angela Chang
ResearchOpen Access05 Sept 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-11
A second Middle Eastern kindred with autosomal recessive non-syndromic hearing loss segregates DFNB9

Suzanne M Leal
Fazil Apaydin
Emilia Vitale
Research19 Oct 1998
European Journal of Human Genetics

Volume: 6, P: 341-344
Strong indication for a breast cancer susceptibility gene on chromosome 8p12-p22: linkage analysis in German breast cancer families

Susanne Seitz
Klaus Rohde
Siegfried Scherneck
Research13 Feb 1997
Oncogene

Volume: 14, P: 741-743
Catecholamine-induced lipolysis in obesity

Peter Arner
Research12 Mar 1999
International Journal of Obesity

Volume: 23, P: S10-S13
Deletion mapping of chromosome 4 in head and neck squamous cell carcinoma

Mark A Pershouse
Adel K El-Naggar
Peter A Steck
Research23 Jan 1997
Oncogene

Volume: 14, P: 369-373
Hunting for human obesity genes? Look in the adipose tissue!

P Arner
Research01 Nov 2000
International Journal of Obesity

Volume: 24, P: S57-S62
Promoter CpG hypermethylation and downregulation of DICE1 expression in prostate cancer

Albrecht Röpke
Peter Buhtz
Peter F Wieacker
Research20 Jun 2005
Oncogene

Volume: 24, P: 6667-6675
Exposure to Polycyclic Aromatic Hydrocarbons Leads to Non-monotonic Modulation of DNA and RNA (hydroxy)methylation in a Rat Model

Radu-Corneliu Duca
Nathalie Grova
Lode Godderis
ResearchOpen Access12 Jul 2018
Scientific Reports

Volume: 8, P: 1-9
Generation of a transcription map distal to HLA-F

Stefano Goldwurm
Benjamin FH Van der Griend
Elizabeth C Jazwinska
Research18 Nov 1998
European Journal of Human Genetics

Volume: 6, P: 475-486
Identification of two QTL influencing upper temperature tolerance in three rainbow trout (Oncorhynchus mykiss) half-sib families

Timothy R Jackson
Moira M Ferguson
Teresa J Crease
Research01 Feb 1998
Heredity

Volume: 80, P: 143-151
A characterization of cis- and trans-heritability of RNA-Seq-based gene expression

Klaasjan G. Ouwens
Rick Jansen
Dorret I. Boomsma
Research26 Sept 2019
European Journal of Human Genetics

Volume: 28, P: 253-263
Extensive protein and microsatellite variability in an isolated, cyclic ungulate population

David R Bancroft
Josephine M Pemberton
Peter King
Research01 Mar 1995
Heredity

Volume: 74, P: 326-336
Sequential orthogonal assays for longitudinal and endpoint characterization of three-dimensional spheroids

The authors present a protocol for the self-assembly of single-cell suspensions into spheroids by the liquid overlay method, followed by a modular framework of orthogonal assays to phenotype spheroids both longitudinally and at an endpoint.

Eva Blondeel
Sam Ernst
Olivier De Wever
Protocols08 Apr 2025
Nature Protocols

Volume: 20, P: 2899-2941
DNA methylation signatures of educational attainment

Jenny van Dongen
Marc Jan Bonder
Bastiaan T. Heijmans
ResearchOpen Access23 Mar 2018
npj Science of Learning

Volume: 3, P: 1-14
TYMS promotes genomic instability and tumor progression in Ink4a/Arf null background

Maria V. Guijarro
Akbar Nawab
Maria Zajac-Kaye
ResearchOpen Access27 Apr 2023
Oncogene

Volume: 42, P: 1926-1939
DNA methylation in peripheral tissues and left-handedness

Veronika V. Odintsova
Matthew Suderman
Jenny van Dongen
ResearchOpen Access04 Apr 2022
Scientific Reports

Volume: 12, P: 1-16
Crosstalk between cellular compartments protects against proteotoxicity and extends lifespan

Matea Perić
Peter Bou Dib
Anita Kriško
ResearchOpen Access27 Jun 2016
Scientific Reports

Volume: 6, P: 1-12
Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

Elisabeth M van Leeuwen
Jennifer E Huffman
Cornelia van Duijn
ResearchOpen Access12 Nov 2015
npj Aging and Mechanisms of Disease

Volume: 1, P: 1-9
Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

Tianye Jia
Congying Chu
Sylvane Desrivières
ResearchOpen Access06 Dec 2019
Molecular Psychiatry

Volume: 26, P: 3884-3895
Genetic risk for major depressive disorder and loneliness in sex-specific associations with coronary artery disease

Jessica Dennis
Julia Sealock
Lea K. Davis
ResearchOpen Access03 Dec 2019
Molecular Psychiatry

Volume: 26, P: 4254-4264
Connecting the dots, genome-wide association studies in substance use

M G Nivard
K J H Verweij
D I Boomsma
News15 Mar 2016
Molecular Psychiatry

Volume: 21, P: 733-735

Search

Filter By:

Search

Quick links