Search

Accidental ingestion of Pb-contaminated soils represents a major route of Pb exposure for humans. Here, the authors show an effective and straightforward approach of drinking cola beverages to reduce blood Pb levels following the ingestion of contaminated soils based on animal models data.

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

The most up-to-date combination of results on the properties of the Higgs boson is reported, which indicate that its properties are consistent with the standard model predictions, within the precision achieved to date.

The ALICE Collaboration provides details on the microscopic mechanism that ends up creating antideuteron in high-energy proton–proton collisions at the Large Hadron Collider.

Adding tunable photon-photon nonlinearities to programmable photonic circuits would greatly extend their capabilities. Here, the authors demonstrate this by embedding a photonic-crystal waveguide nanostructure hosting an InAs quantum dot within a programmable linear optical circuit, and using it to realise a proof-of-concept quantum simulation of anharmonic molecular vibrational dynamics.

This study reveals how pre-mRNA processing factors in Arabidopsis distinctly coordinate cleavage and transcription termination, highlighting complex roles of CPSF, CstF, PAPS1, BORDER proteins, and FPA in efficient mRNA maturation.

Diluted magnetic semiconductors are promising spintronic materials, however the simultaneous doping of charge and magnetic moment has prevented synthesis of bulk samples. This work reports the synthesis of a bulk magnetic semiconductor (Ba_1−xK_x)(Zn_1−yMn_y)₂As₂with Curie temperatures up to 180 K.

Using spin-entangled baryon–antibaryon pairs, the BESIII Collaboration reports on high-precision measurements of potential charge conjugation and parity (CP)-symmetry-violating effects in hadrons.

The ATLAS Collaboration reports the observation of the electroweak production of two jets and a Z-boson pair. This process is related to vector-boson scattering and allows the nature of electroweak symmetry breaking to be probed.

Sc₃In and ZrZn₂ are the only two known itinerant ferromagnets that form from non-magnetic constituents. Now, Svanidze et al.,evidence itinerant antiferromagnetism in TiAu below 36 K using thermodynamic, transport, muon-based and neutron-based measurements, and density functional analysis.

By doping ice with NaCl, it is shown that a flexoelectric coefficient of up to 10 μC m⁻¹ is generated, enabling effective piezoelectric coefficients that are comparable to those of ceramics. This arises from the streaming current of quasi-liquid flow through grain boundaries from one side of the sample to the other.

Despite recent advances with trappedion-based platforms, achieving quantum networks with link efficiency greater than unity on metropolitan scales is still a challenge. Here, the authors demonstrate a multiplexed quantum network generating heralded entanglement at a rate faster than local decoherence.

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

The flagship paper of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium describes the generation of the integrative analyses of 2,658 cancer whole genomes and their matching normal tissues across 38 tumour types, the structures for international data sharing and standardized analyses, and the main scientific findings from across the consortium studies.

Most demonstrations of optical neural networks for computing have been so far limited to real-valued frameworks. Here, the authors implement complex-valued operations in an optical neural chip that integrates input preparation, weight multiplication and output generation within a single device.

The LHCb experiment at CERN has observed significant asymmetries between the decay rates of the beauty baryon and its CP-conjugated antibaryon, thus demonstrating CP violation in baryon decays.

Mechanical relaxation processes in glasses can provide information on the structural and mechanical properties of glasses. Here, the authors observe a fast secondary relaxation process in La-based metallic glasses, providing information on the inelasticity of metallic glasses.

Ferromagnetic systems produced by the transition metal doping of semiconductors may be used as components of spintronic devices. Here, a new ferromagnet, Li_1+y(Zn_1-xMn_x)As, is prepared in bulk quantities and shown to have a critical temperature approaching 50 K.

The mechanisms underlying the ability to remyelinate in aging and disease are unclear. Here, the authors show that DOR-mediated activation of α-ketoglutarate in mature oligodendrocytes can promote myelin production in mice during demyelination and aging.

An increase in the concentration of atmospheric carbon dioxide and warmer temperatures can alter plant growth and development. Here the authors show that these conditions can also elicit significant changes in microRNAs expression, including some which might induce early flowering in Arabidopsis.

Bound states in continuum have attracted attention in various platforms, and recently condensation of bound states in continuum polariton modes was demonstrated at low temperatures. Here the authors report the observation of such a state in a periodic air-hole perovskite-based photonic crystal at room temperature.

Hybrid quantum systems offer increased functionality, however, they require strong coupling between components. Here, Shen and coauthors achieve strong coupling between polaritons, formed by strongly coupled magnons and photons, and phonons, paving the way for polaromechanical hybrid systems.

Better analytical methods are needed to extract biological meaning from genome-wide association studies (GWAS) of psychiatric disorders. Here the authors take GWAS data from over 60,000 subjects, including patients with schizophrenia, bipolar disorder and major depression, and identify common etiological pathways shared amongst them.

Longitudinal proteomics holds great promise for biomarker discovery, but the data interpretation has remained a challenge. Here, the authors evaluate several tools to detect longitudinal differential expression in proteomics data and introduce RolDE, a robust reproducibility optimization approach.

The joint analysis of datasets from NOvA and T2K, the two currently operating long-baseline neutrino oscillation experiments, provides new constraints related to neutrino masses and fundamental symmetries.

An analysis of 2,954 genomes from 38 cancer subtypes identified 19,166 retrotransposition events in 35% of samples. Aberrant LINE-1 retrotranspositions can lead to the deletion of tumor-suppressor genes as well as the amplification of oncogenes.

Whole-genome sequencing data for 2,778 cancer samples from 2,658 unique donors across 38 cancer types is used to reconstruct the evolutionary history of cancer, revealing that driver mutations can precede diagnosis by several years to decades.

The LHCb Collaboration reports the observation of an exotic, narrow, tetraquark state that contains two charm quarks, an up antiquark and a down antiquark.

The coexistence of topological and superconducting states in a single layer of FeSe on a SrTiO₃ substrate is reported.

Sun et al. report human lifespan changes in the brain’s functional connectome in 33,250 individuals, which highlights critical growth milestones and distinct maturation patterns and offers a normative reference for development, aging and diseases.

The integration of liver and plasma quantitative lipidomic and proteomic data from 107 distinct mouse strains provides important insights into regulators of mammalian lipid metabolism.

Macrophage-augmented organoids integrate macrophages into organoids that are cultured from human liver tissue for analysis of immune responses during three different viral infections.

Edge-localized plasma modes in a tokamak can damage its innermost wall. Simulations now show that fast ions can modify the spatio-temporal structure of these modes. These effects need to be considered in the optimization of control techniques.

Realizing tunable metamaterials across a broad spectral range is of great interest. Here, Liu et al. introduce hybrid structures comprising graphene plasmonic resonators strongly coupled to conventional split-ring resonators and reach 60% transmission modulation with an operating speed above 40 MHz.

Electric-field-induced cracks are generally detrimental to functionality of ferroelectric ceramics. Liu et al. use an intermetallic alloy and ferroelectric oxide junction to mediate the reversible formation of cracks at nanoscales, resulting in colossal electroresistance modulation for memory applications.

The anomalous Hall effect has been observed in high-quality epitaxial thin films of non-collinear antiferromagnet Mn₃Pt, and can be switched on and off using an electric field.

The ATLAS Collaboration reports a measurement of the ratio of the decay rates of W bosons to τ leptons and muons, in agreement with universal lepton couplings as postulated in the standard model of particle physics.

Plasma fusion devices like tokamaks are important for energy generation but there are many challenges for their steady state operation. Here, the authors show that full divertor detachment is compatible with high-confinement high-poloidal-beta core plasmas and this prevents the damage to the divertor target plates and the first wall.

Metamaterials can be designed with anisotropy, which tailors their optical properties to enable interesting functionalities. Here, the anisotropy of a Maltese-cross metamaterial is actively controlled by an actuator, allowing for tunable birefringence and dichroism in the terahertz frequency region.

Although LaAlO₃ and SrTiO₃ are both insulators, when they are brought together at a (100) interface, a highly conducting two-dimensional electron gas forms between them. Annandi et al.show that this also happens at a (110) interface, counter to expectations that it should not.

A proper theoretical description for unconventional superconductivity in iron-based compounds remains elusive. Here, the authors, to capture the electron correlation strength and the role of Fermi surfaces, report ARPES measurements of three iron chalcogenide superconductors to establish universal features.

Analysis of 46 newly sequenced or re-sequenced Tausch’s goatgrass (Aegilops tauschii) accessions establishes the origin of the bread wheat (Triticum aestivum) D genome from genetically and geographically discrete Ae. tauschii subpopulations.

Whether multimorbidity accelerates brain Aβ deposition in humans remains largely unknown. Here, the authors demonstrate that higher self-reported multimorbidity burden predicts increased brain Aβ accumulation rates in the ADNI cohort.

Unimolecular integration of NMDA receptor antagonism with GLP-1 receptor agonism effectively reverses obesity, hyperglycaemia and dyslipidaemia in rodent models of metabolic disease.

Myelin formation is regulated by epigenetic mechanisms and ensures proper neuronal function during development and after demyelination. Here, the authors show that TET1, a DNA hydroxymethylase, regulates myelination during development and remyelination in mice.

Memristors are passive electrical components that can act like simple memories. Here, the authors use an array of hafnium oxide memristors to create a type of artificial neural network, known as a Hopfield network, that is capable of retrieving data from partial information

At the Relativistic Heavy Ion Collider, observations of two meson species produced by heavy-ion collisions, ϕ and K^*0, show surprising patterns of global spin alignment, being unexpectedly large and consistent with zero, respectively.

Heavy-atom molecules can possess complicated electronic structures due to pronounced electron correlation and relativistic effects. Here, the authors describe electronic states of RaF in detail by combining accurate spectroscopy and theory approaches.