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Showing 101–150 of 184 results

Advanced filters: Author: R Lindquist Clear advanced filters

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

Montserrat Arrasate
Siddhartha Mitra
Steven Finkbeiner
Research14 Oct 2004
Nature

Volume: 431, P: 805-810
Targeting HSP90 for cancer therapy

D Mahalingam
R Swords
F J Giles
ReviewsOpen Access28 Apr 2009
British Journal of Cancer

Volume: 100, P: 1523-1529
Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols

Relocation of metabolic pathways to yeast mitochondria can increase production levels compared with expression of the same pathways in the cytoplasm.

José L Avalos
Gerald R Fink
Gregory Stephanopoulos
Research17 Feb 2013
Nature Biotechnology

Volume: 31, P: 335-341
Conventional and ambulatory blood pressure and menopause in a prospective population study

JA Staessen
G Ginocchio
R Fagard
Research01 Aug 1997
Journal of Human Hypertension

Volume: 11, P: 507-514
Microsatellite ‘evolution’: directionality or bias?

Hans Ellegren
Craig R. Primmer
Ben C. Sheldon
Correspondence01 Dec 1995
Nature Genetics

Volume: 11, P: 360-362
A genetic analysis of the relationship between life-history variation and heat-shock tolerance in Drosophila buzzatii

Robert A Krebs
Volker Loeschcke
Research01 Jul 1999
Heredity

Volume: 83, P: 46-53
Stimulus arousal drives amygdalar responses to emotional expressions across sensory modalities

Huiyan Lin
Miriam Müller-Bardorff
Thomas Straube
ResearchOpen Access05 Feb 2020
Scientific Reports

Volume: 10, P: 1-12
Artificial photosynthesis for solar water-splitting

Hydrogen from solar-driven water splitting has the potential to provide clean energy. Current progress towards artificial photosynthetic devices is reviewed, with particular focus on visible light active nanostructures. A vision for a future sustainable hydrogen fuel community based on artificial photosynthesis is outlined.

Yasuhiro Tachibana
Lionel Vayssieres
James R. Durrant
Reviews31 Jul 2012
Nature Photonics

Volume: 6, P: 511-518
Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

The authors show that haploinsufficiency of TBK1 causes familial forms of the neurodegenerative diseases ALS and FTD. Loss of binding of a TBK1 protein interaction domain to optineurin, a protein previously linked to ALS, is sufficient to cause the disease. Both proteins regulate autophagy and inflammation.

Axel Freischmidt
Thomas Wieland
Jochen H Weishaupt
Research24 Mar 2015
Nature Neuroscience

Volume: 18, P: 631-636
Genome sequencing and analysis of the model grass Brachypodium distachyon

The genome of the wild grass Brachypodium distachyon (Brachypodium), a member of the Pooideae subfamily, is sequenced. The Pooideae are one of three subfamilies of grasses that provide the bulk of human nutrition and may become major sources of renewable energy. Availability of the genome sequence should help establish Brachypodium as a model for developing new energy and food crops.

John P. Vogel
David F. Garvin
Ivan Baxter
Research11 Feb 2010
Nature

Volume: 463, P: 763-768
The future of model organisms in human disease research

The genetic architecture of human disease is often hard to replicate in model organisms, and disease modelling in human cells is rapidly improving. Six leading model organism researchers provide their perspective on where this leaves non-human models of disease.

Timothy J. Aitman
Charles Boone
Derek L. Stemple
Reviews18 Jul 2011
Nature Reviews Genetics

Volume: 12, P: 575-582
Evolution of gamma knife capsulotomy for intractable obsessive-compulsive disorder

Euripedes C. Miguel
Antonio C. Lopes
Sameer A. Sheth
ReviewsOpen Access09 May 2018
Molecular Psychiatry

Volume: 24, P: 218-240
Recent trends in breast cancer incidence in Sweden

I Persson
R Bergström
HO Adami
Research01 Jan 1998
British Journal of Cancer

Volume: 77, P: 167-169
Evolutionary genomics of the cold-adapted diatom Fragilariopsis cylindrus

The genome of the Southern Ocean phytoplankton Fragilariopsis cylindrus differs markedly from the genomes of its more temperate relatives, with divergent alleles being differentially expressed in environmentally specific conditions such as freezing and darkness.

Thomas Mock
Robert P. Otillar
Igor V. Grigoriev
ResearchOpen Access16 Jan 2017
Nature

Volume: 541, P: 536-540
WEIGHT GAIN AND LINEAR GROWTH ARE INTERRUPTED BY AFRICAN MEASLES

M B Duggan
R D G Milner
Research01 Oct 1985
Pediatric Research

Volume: 19, P: 1089
OPSONIC ACTIVITY OF CORD BLOOD SERA AGAINST VARIOUS SPECIES OF MICRO-ORGANISMS

L Maródi
P C J Leijh
L J Dooren
Research01 Oct 1985
Pediatric Research

Volume: 19, P: 1089
Human chemosignals of disgust facilitate food judgment

Yan Zheng
Yuqi You
Wen Li
ResearchOpen Access19 Nov 2018
Scientific Reports

Volume: 8, P: 1-10
The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis

The genome of the fungus Laccaria bicolor is described; it is of keen interest to evolutionary and plant biologists for its revelations about plant–fungus interactions shaping genomes over time.

F. Martin
A. Aerts
I. V. Grigoriev
ResearchOpen Access06 Mar 2008
Nature

Volume: 452, P: 88-92
Widespread adenine N6-methylation of active genes in fungi

Igor Grigoriev and colleagues perform single-molecule real-time sequencing on 16 diverse fungal species to evaluate levels of adenine methylation (6mA). They find that almost 3% of all adenines are methylated in early-diverging fungi, and they identify clusters of methylated adenines that are enriched at transcription start sites of active genes.

Stephen J Mondo
Richard O Dannebaum
Igor V Grigoriev
Research08 May 2017
Nature Genetics

Volume: 49, P: 964-968
Time-resolved connectome of the five-factor model of personality

L. Passamonti
R. Riccelli
N. Toschi
ResearchOpen Access21 Oct 2019
Scientific Reports

Volume: 9, P: 1-12
The Phaeodactylum genome reveals the evolutionary history of diatom genomes

Chris Bowler
Andrew E. Allen
Igor V. Grigoriev
ResearchOpen Access15 Oct 2008
Nature

Volume: 456, P: 239-244
Fertility Onset, Spermatogenesis, and Pubertal Development in Male Rats: Effect of Graded Underfeeding

Allan R Glass
Damon C Herbert
Jeffrey Anderson
Research01 Nov 1986
Pediatric Research

Volume: 20, P: 1161-1167
Opposing behavioural alterations in male and female transgenic TGFα mice: association with tumour susceptibility

LA Hilakivi-Clarke
PK Arora
RB Dickson
Research01 May 1993
British Journal of Cancer

Volume: 67, P: 1026-1030
Prion protein remodelling confers an immediate phenotypic switch

Prasanna Satpute-Krishnan
Tricia R. Serio
Research08 Sept 2005
Nature

Volume: 437, P: 262-265
Windows of susceptibility to neonatal acute kidney injury and nephron loss in a rabbit model

Shalini Indugula
Sunitha Yarlagadda
Meredith P. Schuh
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-13
Tenascin-cytotactin (TN-C) variants in pseudophakic/aphakic bullous keratopathy corneas

H Maseruka
S M Ataullah
R E Bonshek
Research01 Jul 1998
Eye

Volume: 12, P: 729-734
Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States

Detailed clinical and virologic characteristics of the first 12 individuals with COVID-19 in the United States from the US Centers for Disease Control and Prevention.

Stephanie A. Kujawski
Karen K. Wong
Jing Zhang
Research23 Apr 2020
Nature Medicine

Volume: 26, P: 861-868
The anchorage-dependent and -independent growth of a human SCC cell line: the roles of TGF alpha/EGF and TGFβ

C McLeod
A Thornley
E Scott
Research01 Feb 1990
British Journal of Cancer

Volume: 61, P: 267-269
Metabolite Alterations in Basal Ganglia Associated with Methamphetamine-related Psychiatric Symptoms: A Proton MRS Study

Yoshimoto Sekine
Yoshio Minabe
Norio Mori
Research05 Mar 2002
Neuropsychopharmacology

Volume: 27, P: 453-461
Fiber-optic Sensor for Continuous Monitoring of Fermentation pH

Venetka I. Agayn
David R. Walt
Research01 Jun 1993
Bio/Technology

Volume: 11, P: 726-729
A gravitational wave observatory operating beyond the quantum shot-noise limit

‘Squeezed light’ enables quantum noise in one aspect of light to be reduced by increasing the noise, or more accurately the quantum uncertainty, of a complementary aspect. This has now been used to push the detectors at the heart of the GEO600 gravitational wave observatory to unprecedented levels of sensitivity.

J. Abadie
B. P. Abbott
J. Zweizig
Research11 Sept 2011
Nature Physics

Volume: 7, P: 962-965
An upper limit on the stochastic gravitational-wave background of cosmological origin

A stochastic background of gravitational waves is expected to arise from a superposition of a large number of unresolved gravitational-wave sources and should carry unique signatures from the earliest epochs of the Universe. Limits on the amplitude of the stochastic gravitational-wave background are now reported using the data from a two-year science run of the Laser Interferometer Gravitational-wave Observatory. These limits rule out certain models of early Universe evolution.

B. P. Abbott
R. Abbott
J. Zweizig
Research20 Aug 2009
Nature

Volume: 460, P: 990-994
Uptake and retention of estramustine and the presence of estramustine binding protein in malignant brain tumours in humans

AT Bergenheim
PO Gunnarsson
R Henriksson
Research01 Feb 1993
British Journal of Cancer

Volume: 67, P: 358-361
Brain choline acetyltransferase activity in chronic, human users of cocaine, methamphetamine, and heroin

S J Kish
K S Kalasinsky
L DiStefano
Research22 Jan 1999
Molecular Psychiatry

Volume: 4, P: 26-32
Genetic variability and gene flow in geographical populations of Ceratitis capitata (Wied.) (medfly)

Giuliano Gasperi
Carmela R Guglielmino
Riccardo Milani
Research01 Dec 1991
Heredity

Volume: 67, P: 347-356
Sulphoxythiocarbamates modify cysteine residues in HSP90 causing degradation of client proteins and inhibition of cancer cell proliferation

Y Zhang
S Dayalan Naidu
A T Dinkova-Kostova
ResearchOpen Access05 Dec 2013
British Journal of Cancer

Volume: 110, P: 71-82
Do early infant feeding patterns relate to breast-feeding continuation and weight gain? Data from a longitudinal cohort study

R E Casiday
C M Wright
K N Parkinson
Research31 Mar 2004
European Journal of Clinical Nutrition

Volume: 58, P: 1290-1296
Alpha synuclein is present in Lewy bodies in sporadic Parkinson's disease

E Mezey
A M Dehejia
M H Polymeropoulos
Research10 Nov 1998
Molecular Psychiatry

Volume: 3, P: 493-499
Hebbian plasticity induced by temporally coincident BCI enhances post-stroke motor recovery

Johanna Krueger
Richard Krauth
Catherine M. Sweeney-Reed
ResearchOpen Access12 Aug 2024
Scientific Reports

Volume: 14, P: 1-16
Ongoing harlequin toad declines suggest the amphibian extinction crisis is still an emergency

The status of the harlequin toads has not improved since 2004 despite species rediscoveries accompanied by increasing conservation efforts, and habitat destruction and degradation continue to threaten them today, according to an analysis of population status records over the period 2004–2022.

Stefan Lötters
Amadeus Plewnia
Enrique La Marca
ResearchOpen Access11 Nov 2023
Communications Earth & Environment

Volume: 4, P: 1-8
Selective apoptosis of tandemly duplicated FLT3-transformed leukemia cells by Hsp90 inhibitors

Y Minami
H Kiyoi
T Naoe
Research31 Jul 2002
Leukemia

Volume: 16, P: 1535-1540
U.S. cereal rye winter cover crop growth database

Alexandra M. Huddell
Resham Thapa
Steven B. Mirsky
ResearchOpen Access13 Feb 2024
Scientific Data

Volume: 11, P: 1-7
Rapid on-site amplification and visual detection of misfolded proteins via microfluidic quaking-induced conversion (Micro-QuIC)

Dong Jun Lee
Peter R. Christenson
Sang-Hyun Oh
ResearchOpen Access24 Jul 2024
npj Biosensing

Volume: 1, P: 1-9
mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex

Using whole-transcriptome RNA sequencing at single-nucleotide resolution, this Resource article describes the mRNAs, RNA editing, splice variants and exon-intron boundaries of expressed genes in the cerebral cortex of embryonic and adult mice.

Allissa A Dillman
David N Hauser
Mark R Cookson
Research17 Feb 2013
Nature Neuroscience

Volume: 16, P: 499-506
Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease

B H Kang
M Tavecchio
D C Altieri
ResearchOpen Access01 Feb 2011
British Journal of Cancer

Volume: 104, P: 629-634
Frequent MED12 mutations in phyllodes tumours of the breast

M Yoshida
S Sekine
A Ochiai
ResearchOpen Access02 Apr 2015
British Journal of Cancer

Volume: 112, P: 1703-1708
Randomized phase-II evaluation of letrozole plus dasatinib in hormone receptor positive metastatic breast cancer patients

Devchand Paul
Svetislava J. Vukelja
Joyce O’Shaughnessy
ResearchOpen Access28 Oct 2019
npj Breast Cancer

Volume: 5, P: 1-7
A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci

Nathan A. Kimbrel
Allison E. Ashley-Koch
Jean C. Beckham
Research28 Mar 2022
Molecular Psychiatry

Volume: 27, P: 2264-2272
Epidermal growth factor and transforming growth factor α characteristics of human oral carcinoma cell lines

SS Prime
SM Game
C Scully
Research01 Jan 1994
British Journal of Cancer

Volume: 69, P: 8-15
Bile Salt–Stimulated Lipase and Pancreatic Lipase-Related Protein 2 Are the Dominating Lipases in Neonatal Fat Digestion in Mice and Rats

Xiaonan Li
Susanne Lindquist
Olle Hernell
Research01 Nov 2007
Pediatric Research

Volume: 62, P: 537-541

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