Nature Search

Immunometabolic dysregulation in depression predates illness onset and is associated with lower brain gray matter volume

In this study, Tian et al. use data from the UK Biobank to investigate the course of immunometabolic changes in depression and its impact on structural brain changes.

Ye Ella Tian
Corey Giles
Andrew Zalesky
Research14 Nov 2025
Nature Mental Health

Volume: 3, P: 1555-1566
Calcium enhanced ambient cured fly Ash based geopolymer binders

Mustafa Shamsah
Robin Kalfat
Mude Hanumananaik
ResearchOpen Access15 Jul 2025
Scientific Reports

Volume: 15, P: 1-14
Effect of polygenic scores on the relationship between psychosis and cognition

Lauren Varney
Krisztina Jedlovszky
Elvira Bramon
ResearchOpen Access21 Nov 2025
Translational Psychiatry

Volume: 15, P: 1-12
The network-based underpinnings of persisting symptoms after concussion: a multimodal neuroimaging meta-analysis

Persisting symptoms after concussion (PSaC) present a complex neuropsychiatric challenge with limited treatment options due to inconsistent neuroimaging findings. Here the authors employ a multi-analytic approach to identify the salience network as a core dysfunction hub in PSaC, proposing specific cortical regions as potential targets for personalized neuromodulation therapies.

Adriano Mollica
Robin F. H. Cash
Sean M. Nestor
ResearchOpen Access23 Sept 2025
Nature Mental Health

Volume: 3, P: 1276-1290
A mega-analysis of functional connectivity and network abnormalities in youth depression

This mega-analysis of brain resting-state functional connectivity in young individuals with major depressive disorder scanned at six sites across four countries identified hub regions of the attentional and default mode networks as predictors of depression severity.

Nga Yan Tse
Aswin Ratheesh
Andrew Zalesky
Research23 Sept 2024
Nature Mental Health

Volume: 2, P: 1169-1182
Altered brain activity in unipolar depression unveiled using connectomics

Cash et al. examined whether coordinates derived from neuroimaging studies might delineate a dysfunctional brain network in unipolar depression rather than isolated neuroanatomical foci. The authors found highly robust distributed brain networks that closely recapitulate clinically meaningful models of depression circuitry.

Robin F. H. Cash
Veronika I. Müller
Andrew Zalesky
Research22 Mar 2023
Nature Mental Health

Volume: 1, P: 174-185
Brain stimulation and brain lesions converge on common causal circuits in neuropsychiatric disease

Which brain circuits are causally involved in depression? Using the human connectome as a wiring diagram, Siddiqi et al. combine data from lesions, deep brain stimulation and transcranial magnetic stimulation studies to show that these three methods converge in identifying a single depression circuit.

Shan H. Siddiqi
Frederic L. W. V. J. Schaper
Michael D. Fox
Research08 Jul 2021
Nature Human Behaviour

Volume: 5, P: 1707-1716
Follow-up of men with a PI-RADS 4/5 lesion after negative MRI/Ultrasound fusion biopsy

Kira Kornienko
Miriam Reuter
Hannes Cash
ResearchOpen Access10 Aug 2022
Scientific Reports

Volume: 12, P: 1-7
Long-term cellular immunity of vaccines for Zaire Ebola Virus Diseases

In this immunological ancillary study of the PREVAC trial, the authors show that approved Ebola virus vaccines induce memory T-cell responses that persist during the five year follow-up after initial vaccination.

Aurélie Wiedemann
Edouard Lhomme
Huanying Zhou
ResearchOpen Access03 Sept 2024
Nature Communications

Volume: 15, P: 1-15
Consensus guidelines for the use of concurrent TMS-fMRI in cognitive and clinical neuroscience

We present best practice guidelines for the use of concurrent TMS-fMRI, experimental design, technical requirements and data interpretation, illustrated via 12 use cases.

Alexandra Woolgar
Eva Feredoes
Alexander T. Sack
Reviews24 Jun 2025
Nature Protocols

Volume: 21, P: 1-17
Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

Progressive diseases tend to be heterogeneous in their underlying aetiology mechanism, disease manifestation, and disease time course. Here, Young and colleagues devise a computational method to account for both phenotypic heterogeneity and temporal heterogeneity, and demonstrate it using two neurodegenerative disease cohorts.

Alexandra L Young
Razvan V Marinescu
Ansgar J Furst
ResearchOpen Access15 Oct 2018
Nature Communications

Volume: 9, P: 1-16
Extent of illegal sand mining in the Mekong Delta

Sand mining intensified in the Vietnamese Mekong Delta between 2013 and 2018–2020 with an increase in the allowable rate of sand extraction leading to reductions in the volume of illegally mined sand, according to an analysis of field measurements and government data.

Kai Wan Yuen
Edward Park
Adam D. Switzer
ResearchOpen Access10 Jan 2024
Communications Earth & Environment

Volume: 5, P: 1-13
From neural circuits to communities: an integrative multidisciplinary roadmap for global mental health

In this Perspective, the authors propose a new approach to addressing mental health globally that encompasses a breadth of disciplines, from neuroscience to intervention and implementation sciences.

Michelle G. Craske
Mohammad M. Herzallah
Vikram Patel
Reviews17 Jan 2023
Nature Mental Health

Volume: 1, P: 12-24
36-month durability of ultrasound renal denervation for hypertension resistant to combination therapy in RADIANCE-HTN TRIO

Michael J. Bloch
Ajay J. Kirtane
Patric Kröpil
ResearchOpen Access27 Sept 2024
Hypertension Research

Volume: 47, P: 3467-3472
Evaluation of short interval cortical inhibition and intracortical facilitation from the dorsolateral prefrontal cortex in patients with schizophrenia

Yoshihiro Noda
Mera S. Barr
Daniel M. Blumberger
ResearchOpen Access06 Dec 2017
Scientific Reports

Volume: 7, P: 1-12
Individual deviations from normative models of brain structure in a large cross-sectional schizophrenia cohort

Jinglei Lv
Maria Di Biase
Andrew Zalesky
Research22 Sept 2020
Molecular Psychiatry

Volume: 26, P: 3512-3523
Characterization of Glutamatergic and GABA_A-Mediated Neurotransmission in Motor and Dorsolateral Prefrontal Cortex Using Paired-Pulse TMS–EEG

Robin F H Cash
Yoshihiro Noda
Daniel M Blumberger
Research27 Jul 2016
Neuropsychopharmacology

Volume: 42, P: 502-511
Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe

M Rietschel
M Mattheisen
S Cichon
Research12 Jul 2011
Molecular Psychiatry

Volume: 17, P: 906-917

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