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Showing 1–50 of 56 results

Advanced filters: Author: Rongbin Wang Clear advanced filters

Metabolic engineering of doxorubicin biosynthesis through P450-redox partner optimization and structural analysis of DoxA

Biocatalysis of the chemotherapy drug, doxorubicin, relies on the cytochrome P450 DoxA, which is inefficient. Here, the authors ameliorated the biosynthetic limitations by identifying DoxA redox partners and DnrV, which prevents product inhibition, helping improve microbial production.

Arina Koroleva
Erika Artukka
Mikko Metsä-Ketelä
ResearchOpen Access04 Feb 2026
Nature Communications

P: 1-13
Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues

Macrophage is located in different tissue to serve diverse functions. Here the authors use mass spectrometry and bulk RNA-sequencing to profile 11 mouse macrophage populations from 8 tissues, and combine their de novo data with public datasets to report an integrated proteomic and transcriptomic landscape of mouse macrophage as a valuable resource.

Jingbo Qie
Yang Liu
Chen Ding
ResearchOpen Access30 Nov 2022
Nature Communications

Volume: 13, P: 1-23
Chemoselective synthesis of fluoroacetonitrile-containing terminal groups for stable non-fullerene acceptors

The intrinsic instability of non-fullerene acceptors caused by exocyclic vinyl linkages hampers operational lifetime of organic solar cells. Here, authors introduce F···H interaction in fluoroacetonitrile-containing terminal group for a more planar structure, achieving device efficiency of 19.31%.

Siyuan Li
Zhilong He
Hongliang Zhong
ResearchOpen Access05 Nov 2025
Nature Communications

Volume: 16, P: 1-12
Bright solid-state sources for single photons with orbital angular momentum

Single photons with high orbital angular momenta can act as higher order flying qubits, but efficient generation is scarce. The integration of a single quantum dot emitter into an on-chip mircoring resonator enables the generation of single photons in an orbital angular momentum superposition state.

Bo Chen
Yuming Wei
Xuehua Wang
Research11 Jan 2021
Nature Nanotechnology

Volume: 16, P: 302-307
Early detection of urological tumors based on genomic characteristics of cell-free DNA fragments: a multi-center study

Huiyong Zhang
Caihong Huang
Fubo Wang
ResearchOpen Access17 Nov 2025
npj Precision Oncology

Volume: 9, P: 1-11
SRD5A2 and emerging therapies in androgen-driven disorders

SRD5A2 has clinical relevance in benign prostatic hyperplasia, prostate cancer and other androgen-mediated conditions. In this Review, the authors describe the complementary roles of α-blockers for rapid symptom relief and 5α-reductase inhibitors for disease modification and progression risk reduction in benign prostatic hyperplasia and the potential of targeting SRD5A2 in other androgen-driven disorders.

Zongwei Wang
Boqing Gu
Aria F. Olumi
Reviews07 Jan 2026
Nature Reviews Urology

P: 1-14
Perfluorodecanoic acid stimulates NLRP3 inflammasome assembly in gastric cells

Xiangyu Zhou
Tianyi Dong
Shili Liu
ResearchOpen Access03 Apr 2017
Scientific Reports

Volume: 7, P: 1-10
Author Correction: GPR34 is a metabolic immune checkpoint for ILC1-mediated antitumor immunit

Jiaxian Yan
Chi Zhang
Rongbin Zhou
Amendments and Corrections07 Oct 2024
Nature Immunology

Volume: 25, P: 2167
H₂O₂-mediated oxidation of PHOSPHATE STARVATION RESPONSE2 promotes adaptation to low phosphate in rice

Phosphorus is an essential plant nutrient. Here Meng et al. show that low phosphorus availability stimulates hydrogen peroxide production which in turn promotes the oligomerization, nuclear translocation and DNA binding activity of the PHR2 transcription factor and enhances the phosphate starvation response.

Funing Meng
Dan Xiang
Chuanzao Mao
ResearchOpen Access01 Oct 2025
Nature Communications

Volume: 16, P: 1-18
Publisher Correction: Epigenetic landscape reveals MECOM as an endothelial lineage regulator

Jie Lv
Shu Meng
Lili Zhang
Amendments and CorrectionsOpen Access18 May 2023
Nature Communications

Volume: 14, P: 1
Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity

The small molecule oridonin (Ori) from the traditional Chinese herb Rabdosia rubescens has anti-inflammatory activity. Here the authors show that Ori can be covalently linked to NLRP3 to prevent assembly of the NLRP3 inflammasome, and to ameliorate inflammation in several mouse disease models.

Hongbin He
Hua Jiang
Rongbin Zhou
ResearchOpen Access29 Jun 2018
Nature Communications

Volume: 9, P: 1-12
Construction of a nomogram for predicting the prognosis of patients with cervical spondylotic myelopathy: a retrospective study

He Ling
Gaoyong Deng
Zhao Huang
ResearchOpen Access30 Dec 2024
Scientific Reports

Volume: 14, P: 1-12
A solid-state source of strongly entangled photon pairs with high brightness and indistinguishability

Embedding GaAs quantum dots in broadband photonic nanostructures allows a source of entangled photons to be fabricated with simultaneous enhancements of the most important parameters.

Jin Liu
Rongbin Su
Xuehua Wang
Research22 Apr 2019
Nature Nanotechnology

Volume: 14, P: 586-593
CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation

The NLRP3 inflammasome is key to the regulation of innate immunity against pathogens or stress, but the underlying signaling regulation is still unclear. Here the authors show that chloride intracellular channels (CLIC) interface between mitochondria stress and inflammasome activation to modulate inflammatory responses.

Tiantian Tang
Xueting Lang
Rongbin Zhou
ResearchOpen Access04 Aug 2017
Nature Communications

Volume: 8, P: 1-12
GPR34 is a metabolic immune checkpoint for ILC1-mediated antitumor immunity

Zhou and colleagues find that GPR34 is a metabolic immune checkpoint for ILC1-mediated antitumor immunity.

Jiaxian Yan
Chi Zhang
Rongbin Zhou
Research02 Oct 2024
Nature Immunology

Volume: 25, P: 2057-2067
Epigenetic landscape reveals MECOM as an endothelial lineage regulator

Errors in vascular development are associated with several congenital defects. Here they systematically investigated the epigenetic landscape of the endothelial lineage and found that MECOM depletion impairs endothelial cell differentiation and angiogenesis.

Jie Lv
Shu Meng
Lili Zhang
ResearchOpen Access25 Apr 2023
Nature Communications

Volume: 14, P: 1-17
Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity

Huang et al. show that, in response to chemotherapy, PTEN directly interacts with NLRP3 in myeloid cells to enhance inflammasome activation and antitumour immune responses.

Yi Huang
Huanyu Wang
Rongbin Zhou
Research04 May 2020
Nature Cell Biology

Volume: 22, P: 716-727
Platelet to lymphocyte ratio was a risk factor in Perthes disease

TianTian Wang
XiaoLin Luo
XiaoFei Ding
ResearchOpen Access28 Mar 2023
Scientific Reports

Volume: 13, P: 1-5
Retinoblastoma protein as an intrinsic BRD4 inhibitor modulates small molecule BET inhibitor sensitivity in cancer

Here the authors identify retinoblastoma (RB) protein as an intrinsic inhibitor of BRD4 and demonstrate that loss of RB induces BRD4 cistrome changes in the genome and enrichment of GPCR-cAMP signaling pathway, conferring resistance to small molecule BET inhibitor.

Donglin Ding
Rongbin Zheng
Haojie Huang
ResearchOpen Access23 Oct 2022
Nature Communications

Volume: 13, P: 1-15
Scalable, full-colour and controllable chromotropic plasmonic printing

Plasmonics offers an alternative approach to robust colour printing, but real applications require a full-colour and scalable process. Here, the authors develop such an approach by combining plasmonic broadband absorbers with conjugate twin-phase modulation, demonstrating its potential for anticounterfeiting technology.

Jiancai Xue
Zhang-Kai Zhou
Xue-Hua Wang
ResearchOpen Access16 Nov 2015
Nature Communications

Volume: 6, P: 1-9
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1

Zhang and colleagues report a function of the glycolytic enzyme α-Enolase 1 in iron homeostasis. In this setting it promotes the mRNA decay of IRP1, thereby suppressing ferroptosis in hepatocellular carcinoma.

Tong Zhang
Linchong Sun
Huafeng Zhang
Research09 Dec 2021
Nature Cancer

Volume: 3, P: 75-89
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis

Li and colleagues show how cMyc promotes tumourigenesis by promoting succinate dehydrogenase complex subunit A acetylation by activating SKP2-mediated degradation of SIRT3. This leads to succinate accumulation and consequent tumour-specific gene expression.

Shi-Ting Li
De Huang
Ping Gao
Research16 Mar 2020
Nature Metabolism

Volume: 2, P: 256-269
Alternations of interhemispheric functional connectivity in children with strabismus and amblyopia: a resting-state fMRI study

Jiaxin Peng
Fan Yao
Yi Shao
ResearchOpen Access23 Jul 2021
Scientific Reports

Volume: 11, P: 1-7
Impaired lipid biosynthesis hinders anti-tumor efficacy of intratumoral iNKT cells

Lipid metabolism has been linked to iNKT function largely as it impacts processing and presentation of lipids they recognize. Here the authors show that iNKT-intrinsic lipid biosynthesis is important for their function but is impaired in tumors, and its restoration with PPARγ agonist drugs promotes anti-tumor iNKT response.

Sicheng Fu
Kaixin He
Li Bai
ResearchOpen Access23 Jan 2020
Nature Communications

Volume: 11, P: 1-15
Influence of ulnar bow sign on surgical treatment of missed Bado type I Monteggia fracture in children

Shijie Liao
Tiantian Wang
Xiaofei Ding
ResearchOpen Access17 Jun 2022
Scientific Reports

Volume: 12, P: 1-8
Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity

Mitochondria must be juxtaposed to phagosomes to supply reactive oxygen species for effective killing of microbes. Zhou and colleagues demonstrate that the kinases Mst1 and Mst2 are important for controlling this redistribution of mitochondria.

Jing Geng
Xiufeng Sun
Dawang Zhou
Research28 Sept 2015
Nature Immunology

Volume: 16, P: 1142-1152
Explainable hybrid transformer for multi-classification of lung disease using chest X-rays

Xiaoyang Fu
Rongbin Lin
Yanchun Liang
ResearchOpen Access24 Feb 2025
Scientific Reports

Volume: 15, P: 1-19
Structural changes in the retina and choroid in patients with different degrees of myopia

Rongbin Liang
Rundong Yang
Xiaodong Zhou
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-12
The Kalanchoë genome provides insights into convergent evolution and building blocks of crassulacean acid metabolism

Crassulacean acid metabolism (CAM) is a metabolic adaptation of photosynthesis that enhances water use efficiency. Here, via genomic analysis of Kalanchoë, the authors provide evidence for convergent evolution of protein sequence and temporal gene expression underpinning the multiple independent emergences of CAM.

Xiaohan Yang
Rongbin Hu
Gerald A. Tuskan
ResearchOpen Access01 Dec 2017
Nature Communications

Volume: 8, P: 1-15
A deterministic quantum dot micropillar single photon source with >65% extraction efficiency based on fluorescence imaging method

Shunfa Liu
Yuming Wei
Siyuan Yu
ResearchOpen Access25 Oct 2017
Scientific Reports

Volume: 7, P: 1-7
Spatial resolution effect of light coupling structures

Juntao Li
Kezheng Li
Emiliano R. Martins
ResearchOpen Access18 Dec 2015
Scientific Reports

Volume: 5, P: 1-8
Effects of Intensive Blood Pressure Reduction on Acute Intracerebral Hemorrhage: A Systematic Review and Meta-analysis

Shun Gong
Chao Lin
Lijun Hou
ResearchOpen Access06 Sept 2017
Scientific Reports

Volume: 7, P: 1-9
Genetic variants in interferon-λ 4 influences HCV clearance in Chinese Han population

Peng Huang
Yinan Yao
Rongbin Yu
ResearchOpen Access10 Feb 2017
Scientific Reports

Volume: 7, P: 1-8
Salinomycin and oxaliplatin synergistically enhances cytotoxic effect on human colorectal cancer cells in vitro and in vivo

Fang Liu
Rongbin Lv
Min Wang
ResearchOpen Access23 Apr 2025
Scientific Reports

Volume: 15, P: 1-13
The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation

Mycobacterium tuberculosis secretes a protein, PtpA, that dephosphorylates proteins in the host cell cytoplasm, weakening immune responses. Here, the authors show that PtpA also enters the nucleus, affects the expression of several host genes, and promotes proliferation and migration of a cancer cell line.

Jing Wang
Pupu Ge
Cui Hua Liu
ResearchOpen Access15 Aug 2017
Nature Communications

Volume: 8, P: 1-16
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway

The mechanisms by which viruses activate the NLRP3 inflammasome remain unclear. Zhou and colleagues show that RNA viruses initiate a RIP1-RIP3 complex that drives mitochondrial damage and activation of the NLRP3 inflammasome independently of necrosis.

Xiaqiong Wang
Wei Jiang
Rongbin Zhou
Research19 Oct 2014
Nature Immunology

Volume: 15, P: 1126-1133
Association Study between Hypertension and A/G Polymorphism at Codon 637 of the Transporter Associated with Antigen Processing 1 Gene

Chong Shen
Zhirong Guo
Cailiang Yao
Research01 Aug 2007
Hypertension Research

Volume: 30, P: 683-690
A small molecule directly targets NLRP3 to promote inflammasome activation and antitumor immunity

Xuemei Liu
Hongbin He
Rongbin Zhou
ResearchOpen Access04 Apr 2025
Cell Death & Disease

Volume: 16, P: 1-10
Disulfidptosis-related genes serve as potential prognostic biomarkers and indicate tumor microenvironment characteristics and immunotherapy response in prostate cancer

Rongbin Zhou
Dingjin Lu
Fubo Wang
ResearchOpen Access19 Jun 2024
Scientific Reports

Volume: 14, P: 1-20
Goldenhar syndrome in a 5-year-old child

Rongbin Liang
Tao Li
Xiaodong Zhou
Research02 Sept 2024
Eye

Volume: 39, P: 141-143
Populus trichocarpa encodes small, effector-like secreted proteins that are highly induced during mutualistic symbiosis

Jonathan M. Plett
Hengfu Yin
Xiaohan Yang
ResearchOpen Access23 Mar 2017
Scientific Reports

Volume: 7, P: 1-13
GPR34 senses demyelination to promote neuroinflammation and pathologies

Bolong Lin
Yubo Zhou
Rongbin Zhou
Research19 Jul 2024
Cellular & Molecular Immunology

Volume: 21, P: 1131-1144
An encryption algorithm for color images based on an improved dual-chaotic system combined with DNA encoding

Rongbin Li
Tingting Liu
Jun Yin
ResearchOpen Access05 Sept 2024
Scientific Reports

Volume: 14, P: 1-18
Demyelination-derived lysophosphatidylserine promotes microglial dysfunction and neuropathology in a mouse model of Alzheimer’s disease

Yubo Zhou
Zonghui Huang
Rongbin Zhou
Research01 Jan 2025
Cellular & Molecular Immunology

Volume: 22, P: 134-149
A lncRNA from an inflammatory bowel disease risk locus maintains intestinal host-commensal homeostasis

Hongdi Ma
Taidou Hu
Shu Zhu
ResearchOpen Access13 Apr 2023
Cell Research

Volume: 33, P: 372-388
A novel polymorphism near HLA class II region is associated with spontaneous clearance of HCV and response to interferon treatment in Chinese patients

Yin Xu
Peng Huang
Rongbin Yu
Research03 Dec 2015
Journal of Human Genetics

Volume: 61, P: 301-305
Comparative chloroplast genome analysis of seven extant Citrullus species insight into genetic variation, phylogenetic relationships, and selective pressure

Cong Zhou
Putao Wang
Qianglong Zhu
ResearchOpen Access25 Apr 2023
Scientific Reports

Volume: 13, P: 1-14
Genetic mutations in NF-κB pathway genes were associated with the protection from hepatitis C virus infection among Chinese Han population

Ming Yue
Ting Tian
Peng Huang
ResearchOpen Access25 Jul 2019
Scientific Reports

Volume: 9, P: 1-11
Genetic variations in NF-κB were associated with the susceptibility to hepatitis C virus infection among Chinese high-risk population

Ting Tian
Jie Wang
Ming Yue
ResearchOpen Access08 Jan 2018
Scientific Reports

Volume: 8, P: 1-8
Retroversion of the hemipelvis rather than hypoplastic posterior wall decreases acetabular anteversion in hips affected by Perthes disease

Shijie Liao
Manjun Zhao
Xiaofei Ding
ResearchOpen Access13 Aug 2021
Scientific Reports

Volume: 11, P: 1-12

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