Circular RNAs (circRNAs) play important roles in many lung diseases. This study investigated the role of circHECTD1 in acute lung injury (ALI). circHECTD1 attenuates the apoptosis of alveolar epithelial cells in lipopolysaccharide-induced ALI through the miR-320a/PIK3CA and miR-136/Sirt1 pathways, indicating a novel therapeutic target for ALI.
- Hongbin Li
- Xiaoxuan Niu
- Min Gao