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Showing 1–50 of 77 results

Advanced filters: Author: S. Michalak Clear advanced filters

Inhibition of nuclear hormone receptor activity by calreticulin

Shoukat Dedhar
Paul S. Rennie
Vincent Giguère
Research03 Feb 1994
Nature

Volume: 367, P: 480-483
Modulation of gene expression by calreticulin binding to the glucocorticoid receptor

Kimberly Burns
Brenda Duggan
Marek Michalak
Research03 Feb 1994
Nature

Volume: 367, P: 476-480
Sulfonated polybenzimidazole for low-alkalinity ion solvating membrane water electrolysis

KOH-doped membranes, so-called ion-solvating membranes (ISMs), have been used in alkaline water electrolysers but face challenges with stability and narrow operational windows. Here a non-crosslinked, partially sulfonated polybenzimidazole ISM with enhanced conductivity and stability is reported, achieving high current densities and prolonged operation.

Muhammad Mara Ikhsan
Chaeyeon Yang
Dirk Henkensmeier
ResearchOpen Access10 Oct 2025
Nature Energy

Volume: 10, P: 1347-1359
Nanopatterning Si(111) surfaces as a selective surface-chemistry route

The ability to control the surface chemistry of silicon is important for microelectronic applications. Chemical species can now be stabilized on Si(111) surfaces using a partially alkoxylated surface as a nanopatterning template.

David J. Michalak
Sandrine Rivillon Amy
Yves J. Chabal
Research10 Jan 2010
Nature Materials

Volume: 9, P: 266-271
Localization of Erythropoietin in Glomeruli of Sheep Kidney by Fluorescent Antibody Technique

JAMES W. FISHER
GEOFFREY TAYLOR
D. D. PORTEOUS
Research06 Feb 1965
Nature

Volume: 205, P: 611-612
The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity

Failure to clear apoptotic cells can lead to autoinflammatory disease. Means and colleagues demonstrate that the receptor SCARF1 recognizes C1q-bound apoptotic cells, which leads to their clearance and prevents lupus-like symptoms.

Zaida G Ramirez-Ortiz
William F Pendergraft III
Terry K Means
Research28 Jul 2013
Nature Immunology

Volume: 14, P: 917-926
Dp71 can restore the dystrophin-associated glycoprotein complex in muscle but fails to prevent dystrophy

Gregory A. Cox
Yoshihide Sunada
Jeffrey S. Chamberlain
Research01 Dec 1994
Nature Genetics

Volume: 8, P: 333-339
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Major agricultural changes required to mitigate phosphorus losses under climate change

The impact of climate change on phosphorus (P) loss from land to water is unclear. Here, the authors use P flux data, climate simulations and P transfer models to show that only large scale agricultural change will limit the effect of climate change on average winter P loads in three catchments across the UK.

M. C. Ockenden
M. J. Hollaway
P. M. Haygarth
ResearchOpen Access31 Jul 2017
Nature Communications

Volume: 8, P: 1-9
Impact of cryopreservation on DNA damage in Acer platanoides L. seeds evaluated by the comet assay

Beata P. Plitta-Michalak
Alice A. Ramos
Marcin Michalak
ResearchOpen Access05 Jul 2025
Scientific Reports

Volume: 15, P: 1-14
Renal disease susceptibility and hypertension are under independent genetic control in the fawn-hooded rat

Donna M. Brown
Abraham P. Provoost
Howard J. Jacob
Research01 Jan 1996
Nature Genetics

Volume: 12, P: 44-51
Coupling of the Na⁺/Ca²⁺exchanger, Na⁺/K⁺ pump and sarcoplasmic reticulum in smooth muscle

Edwin D. W. Moore
Elaine F. Etter
Fredric S. Fay
Research01 Oct 1993
Nature

Volume: 365, P: 657-660
Practical diagnosis of cirrhosis in non-alcoholic fatty liver disease using currently available non-invasive fibrosis tests

The practical rules for the early non-invasive diagnosis of cirrhosis in NAFLD are not well defined. Here, the authors develop and validate two diagnostic tools: a stepwise stratification algorithm including a cirrhosis group, and a risk prediction chart providing a personalized assessment of the individual probability of cirrhosis.

Jérôme Boursier
Marine Roux
Philip N. Newsome
ResearchOpen Access26 Aug 2023
Nature Communications

Volume: 14, P: 1-11
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
An international 20 country patient and physician survey of the usability and acceptability of Stepped Care pathway in Parkinson’s disease

K. Poplawska-Domaszewicz
C. Rodriguez-Blazquez
K. Ray Chaudhuri
ResearchOpen Access13 Nov 2025
Scientific Reports

Volume: 15, P: 1-9
Deep learning-based phenotyping reclassifies combined hepatocellular-cholangiocarcinoma

Combined hepatocellular-cholangiocarcinomas (cHCC-CCA) are challenging to diagnose, as they exhibit features of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICCA). Here, the authors use deep learning to re-classify cHCC-CCA tumours into HCC or ICCA based on histopathology images.

Julien Calderaro
Narmin Ghaffari Laleh
Jakob Nikolas Kather
ResearchOpen Access14 Dec 2023
Nature Communications

Volume: 14, P: 1-10
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1

Nicholas D Huntington
Hamsa Puthalakath
Andreas Strasser
Research08 Jul 2007
Nature Immunology

Volume: 8, P: 856-863
Author Correction: Qubits made by advanced semiconductor manufacturing

A. M. J. Zwerver
T. Krähenmann
J. S. Clarke
Amendments and CorrectionsOpen Access27 Apr 2022
Nature Electronics

Volume: 5, P: 319
Bid can mediate a pro-apoptotic response to etoposide and ionizing radiation without cleavage in its unstructured loop and in the absence of p53

C Maas
E de Vries
J Borst
ResearchOpen Access21 Mar 2011
Oncogene

Volume: 30, P: 3636-3647
Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) is an anti-inflammatory drug proposed as a treatment for COVID19. Here the results are reported from a randomised trial testing DMF treatment in 713 patients hospitalised with COVID-19. DMF was not associated with any improvement in day 5 outcomes.

Peter Sandercock
Janet Darbyshire
Martin J. Landray
ResearchOpen Access31 Jan 2024
Nature Communications

Volume: 15, P: 1-13
A compendium of human gene functions derived from evolutionary modelling

Evolutionary modelling and expert review are applied to integrate experimentally supported knowledge accumulated in the Gene Ontology knowledgebase to create a draft human gene ‘functionome’.

Marc Feuermann
Huaiyu Mi
Paul D. Thomas
ResearchOpen Access26 Feb 2025
Nature

Volume: 640, P: 146-154
Transcriptome-wide signature of hybrid breakdown associated with intrinsic reproductive isolation in lake whitefish species pairs (Coregonus spp. Salmonidae)

S Renaut
L Bernatchez
Research01 Dec 2010
Heredity

Volume: 106, P: 1003-1011
Evolution at Spike protein position 519 in SARS-CoV-2 facilitated adaptation to humans

C. Cereghino
K. Michalak
P. Michalak
ResearchOpen Access09 Jul 2024
npj Viruses

Volume: 2, P: 1-9
Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs

Decellularized whole porcine livers revascularized with human endothelial cells and implanted heterotopically into immunosuppressed pigs whose spleens had been removed can sustain perfusion for up to 15 days.

Mohammed F. Shaheen
Dong Jin Joo
Scott L. Nyberg
Research14 Oct 2019
Nature Biomedical Engineering

Volume: 4, P: 437-445
Genetic mechanisms of critical illness in COVID-19

A genome-wide association study of critically ill patients with COVID-19 identifies genetic signals that relate to important host antiviral defence mechanisms and mediators of inflammatory organ damage that may be targeted by repurposing drug treatments.

Erola Pairo-Castineira
Sara Clohisey
J. Kenneth Baillie
Research11 Dec 2020
Nature

Volume: 591, P: 92-98
Dodecamer repeat expansion in cystatin B gene in progressive myoclonus epilepsy

Maria D. Lalioti
Hamish S. Scott
Stylianos E. Antonarakis
Research24 Apr 1997
Nature

Volume: 386, P: 847-851
Author Correction: Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs

Mohammed F. Shaheen
Dong Jin Joo
Scott L. Nyberg
Amendments and Corrections05 Nov 2019
Nature Biomedical Engineering

Volume: 4, P: 476
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Telemedicine retinopathy of prematurity severity score (TeleROP-SS) versus modified activity score (mROP-ActS) retrospective comparison in SUNDROP cohort

Christine L. Xu
Joel Adu-Brimpong
Darius M. Moshfeghi
ResearchOpen Access14 Sept 2023
Scientific Reports

Volume: 13, P: 1-7
Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab

Vaccination is effective in protecting from COVID-19. Here the authors report immune responses and breakthrough infections in twice-vaccinated patients receiving anti-TNF treatments for inflammatory bowel disease, and find dampened vaccine responses that implicate the need of adapted vaccination schedules for these patients.

Simeng Lin
Nicholas A. Kennedy
Jeannie Bishop
ResearchOpen Access16 Mar 2022
Nature Communications

Volume: 13, P: 1-14
Qubits made by advanced semiconductor manufacturing

Silicon spin qubits can be fabricated in a 300 mm semiconductor manufacturing facility using all-optical lithography and fully industrial processing.

A. M. J. Zwerver
T. Krähenmann
J. S. Clarke
ResearchOpen Access29 Mar 2022
Nature Electronics

Volume: 5, P: 184-190
Improved vascular response to a novel polymeric blend PLLA/PLGA coronary scaffold material: preclinical study

Piotr P. Buszman
Mateusz Kachel
Paweł E. Buszman
ResearchOpen Access01 Oct 2025
Scientific Reports

Volume: 15, P: 1-11
Calreticulin promotes cell motility and enhances resistance to anoikis through STAT3–CTTN–Akt pathway in esophageal squamous cell carcinoma

X-L Du
H Yang
M-R Wang
Research17 Aug 2009
Oncogene

Volume: 28, P: 3714-3722
Chitosan nanoencapsulation of Turbinaria triquetra metabolites in the management of podocyturia in nephrotoxic rats

Abdullah Abdel-Aal
Abdel-Aziz A. F.
Abdelhamid Aly Hamdy
ResearchOpen Access03 Jan 2025
Scientific Reports

Volume: 15, P: 1-16
S100A6 (Calcyclin) is a prostate basal cell marker absent in prostate cancer and its precursors

I Rehman
S S Cross
F C Hamdy
ResearchOpen Access27 Jul 2004
British Journal of Cancer

Volume: 91, P: 739-744
Placebos without deception reduce self-report and neural measures of emotional distress

There is controversy about whether placebos without deception cause real psychobiological benefits. Here, the authors show that the positive effects of placebos without deception are more than response bias by providing evidence they can reduce self-report and neural measures of emotional distress.

Darwin A. Guevarra
Jason S. Moser
Ethan Kross
ResearchOpen Access29 Jul 2020
Nature Communications

Volume: 11, P: 1-8
Widespread persistent changes to temperature extremes occurred earlier than predicted

Chao Li
Yuanyuan Fang
Anna M. Michalak
ResearchOpen Access17 Jan 2018
Scientific Reports

Volume: 8, P: 1-8
To which world regions does the valence–dominance model of social perception apply?

Jones et al. examine the generalizability of the valence–dominance model of social judgements of faces in 41 countries across 11 world regions. They find evidence of both generalizability and variation, depending on the analytical method.

Benedict C. Jones
Lisa M. DeBruine
Nicholas A. Coles
Research04 Jan 2021
Nature Human Behaviour

Volume: 5, P: 159-169
The Cacna1h mutation in the GAERS model of absence epilepsy enhances T-type Ca²⁺ currents by altering calnexin-dependent trafficking of Ca_v3.2 channels

Juliane Proft
Yuriy Rzhepetskyy
Norbert Weiss
ResearchOpen Access14 Sept 2017
Scientific Reports

Volume: 7, P: 1-13
IL-27 disturbs lipid metabolism and restrains mitochondrial activity to inhibit γδ T17 cell-mediated skin inflammation

Mingyue Zhang
Dehai Li
Qian Wang
ResearchOpen Access09 Jul 2024
Cell Death & Disease

Volume: 15, P: 1-12
The structural and functional diversity of dystrophin

Andrew H. Ahn
Louis M. Kunkel
Reviews01 Apr 1993
Nature Genetics

Volume: 3, P: 283-291
Ameliorative effect of oregano (Origanum vulgare) versus silymarin in experimentally induced hepatic encephalopathy

Eman A. R. Abdelghffar
Heba A. S. El-Nashar
Omayma A. Eldahshan
ResearchOpen Access25 Oct 2022
Scientific Reports

Volume: 12, P: 1-17
The design of drugs for HIV and HCV

Drug development for HIV has been the major driving force in antiviral research. The strategies that are now being pursued for combating hepatitis C virus (HCV) are remarkably reminiscent of those established for HIV. Here, De Clercq reviews aspects of the medicinal chemistry and history of drug design for HIV and HCV.

Erik De Clercq
Reviews01 Dec 2007
Nature Reviews Drug Discovery

Volume: 6, P: 1001-1018
Isolation and characterization of human cKIT positive amniotic fluid stem cells obtained from pregnancies with spina bifida

Katarzyna Michalak-Micka
Nadine Huerlimann
Ueli Moehrlen
ResearchOpen Access06 Jun 2025
Scientific Reports

Volume: 15, P: 1-15
The p53 family and programmed cell death

E C Pietsch
S M Sykes
M E Murphy
Reviews27 Oct 2008
Oncogene

Volume: 27, P: 6507-6521
Different HPV16 E6/E7 oncogene expression patterns in epithelia reconstructed from HPV16-immortalized human endocervical cells and genital keratinocytes

Qi Sun
Shou-Ching Tang
Alan Pater
Research13 Nov 1997
Oncogene

Volume: 15, P: 2399-2408
An ultra-stable gold-coordinated protein cage displaying reversible assembly

An artificial protein cage is readily assembled by metal ion coordination and disassembled by reducing agents, and displays excellent chemical and thermal stability.

Ali D. Malay
Naoyuki Miyazaki
Jonathan G. Heddle
Research08 May 2019
Nature

Volume: 569, P: 438-442
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
Classification performance assessment for imbalanced multiclass data

Jesús S. Aguilar-Ruiz
Marcin Michalak
ResearchOpen Access10 May 2024
Scientific Reports

Volume: 14, P: 1-10

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