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Showing 1–7 of 7 results
Advanced filters: Author: Samuel Doré Clear advanced filters
  • Mapping of the neutrophil compartment using single-cell transcriptional data from multiple physiological and patological states reveals its organizational architecture and how cell state dynamics and trajectories vary during health, inflammation and cancer.

    • Daniela Cerezo-Wallis
    • Andrea Rubio-Ponce
    • Iván Ballesteros
    ResearchOpen Access
    Nature
    Volume: 649, P: 1003-1012
  • The spatial architecture of the lung cancer microenvironment could influence the survival outlook and therapeutic options of patients. Here the authors find distinct patterns and composition of immune cells when comparing lung adenocarcinomas and lung squamous cell carcinomas, paving way for precision immune therapy according to histological subtype.

    • Lysanne Desharnais
    • Mark Sorin
    • Logan A. Walsh
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-12
  • Using imaging mass cytometry, the tumour and immunological spatial landscapes of 416 lung adenocarcinomas are characterized, which, when combined with deep learning, can predict clinical outcomes with high accuracy.

    • Mark Sorin
    • Morteza Rezanejad
    • Logan A. Walsh
    ResearchOpen Access
    Nature
    Volume: 614, P: 548-554
  • Imaging mass cytometry of human brain tumours provides spatial information that, combined with existing transcriptomic data, reveals the existence of a cellular neighbourhood containing a rare macrophage population associated with prolonged survival.

    • Elham Karimi
    • Miranda W. Yu
    • Logan A. Walsh
    ResearchOpen Access
    Nature
    Volume: 614, P: 555-563