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Advanced filters: Author: Shencun Fang Clear advanced filters

Extracellular matrix anchored neutrophils drive pulmonary fibrosis in mice

Pulmonary fibrosis involves chronic inflammation and extracellular matrix remodeling but the contribution of neutrophils is unclear. Here the authors show that reverse-migrating neutrophils anchored in the lung extracellular matrix exacerbate fibrosis via ICAM1 and macrophage derived cathepsin C.

Liliang Yang
Piaopiao Sun
Jie Chao
ResearchOpen Access26 Nov 2025
Nature Communications

Volume: 16, P: 1-19
Serial monitoring of cerebrospinal fluid in patients with leptomeningeal metastases in lung cancer via the Ommaya reservoir as a predictive indicator of therapeutic efficacy and clinical prognosis

Hehui Fang
Haitao Luo
Shencun Fang
ResearchOpen Access14 Dec 2025
npj Precision Oncology

Volume: 10, P: 1-11
circHECTD1 promotes the silica-induced pulmonary endothelial–mesenchymal transition via HECTD1

Shencun Fang
Huifang Guo
Jie Chao
ResearchOpen Access14 Mar 2018
Cell Death & Disease

Volume: 9, P: 1-16
p53/PUMA expression in human pulmonary fibroblasts mediates cell activation and migration in silicosis

Wei Wang
Haijun Liu
Jie Chao
ResearchOpen Access18 Nov 2015
Scientific Reports

Volume: 5, P: 1-12
BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silicosis

Haijun Liu
Yusi Cheng
Hong Liao
ResearchOpen Access09 Mar 2017
Cell Death & Disease

Volume: 8, P: e2657