Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

View all journals
Search
Log in

nature
search

Search

Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Cell Research (3)
Scientific Reports (2)
Acta Pharmacologica Sinica (1)
Cell Death and Differentiation (1)
Cell Death & Disease (1)

Choose more journals

Article type Check one or more article types to show results from those article types only.

Research (12)

Subject Check one or more subjects to show results from those subjects only.

Biochemistry
Biomarkers
Biophysics
Biotechnology
Cancer
Cell biology
Chemical biology
Diseases
Drug discovery
Molecular biology
Neuroscience

Date Choose a date option to show results from those dates only.

Today
Last 7 days
Last 30 days
Last 12 months
Last 2 years
Last 5 years

Custom date range

Clear all filters

Sort by:

Relevance

Date published (new to old)

Date published (old to new)

Showing 1–12 of 12 results

Advanced filters: Author: Shouqing Luo Clear advanced filters

Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response

The autophagy protein p62 undergoes liquid-liquid phase separation but how this is regulated is unclear. Here, the authors report that the histone chaperone DAXX interacts with p62 in the cytoplasm to drive its phase separation.

Yi Yang
Thea L. Willis
Shouqing Luo
ResearchOpen Access21 Aug 2019
Nature Communications

Volume: 10, P: 1-18
Gelation of cytoplasmic expanded CAG RNA repeats suppresses global protein synthesis

Pan, Lu, Feng, Lu et al. demonstrated that CAG repeat expansion RNAs can form gel-like condensates in the cytoplasm and sequester the translation elongation factor eEF2, leading to suppressed global protein synthesis and neurodegeneration-relevant phenotypes.

Yuyin Pan
Junmei Lu
Boxun Lu
Research17 Aug 2023
Nature Chemical Biology

Volume: 19, P: 1372-1383
Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds

Compounds that interact with mutant huntingtin and an autophagosomal protein are able to reduce cellular levels of mutant huntingtin by targeting it for autophagic degradation, demonstrating an approach that may have potential for treating proteopathies.

Zhaoyang Li
Cen Wang
Boxun Lu
Research30 Oct 2019
Nature

Volume: 575, P: 203-209
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Brinda Ravikumar
Coralie Vacher
David C Rubinsztein
Research16 May 2004
Nature Genetics

Volume: 36, P: 585-595
The caspase-6–p62 axis modulates p62 droplets based autophagy in a dominant-negative manner

Evelina Valionyte
Yi Yang
Shouqing Luo
ResearchOpen Access03 Dec 2021
Cell Death & Differentiation

Volume: 29, P: 1211-1227
Alcohol use disorder disrupts BDNF maturation via the PAI-1 pathway which could be reversible with abstinence

Shouqing Liu
Xin’e Xie
Zhirong Yang
ResearchOpen Access27 Sept 2024
Scientific Reports

Volume: 14, P: 1-11
Blood biomarker-based classification study for neurodegenerative diseases

Jack Kelly
Rana Moyeed
Xinzhong Li
ResearchOpen Access11 Oct 2023
Scientific Reports

Volume: 13, P: 1-10
Degradation of lipid droplets by chimeric autophagy-tethering compounds

Yuhua Fu
Ningxie Chen
Boxun Lu
ResearchOpen Access08 Jul 2021
Cell Research

Volume: 31, P: 965-979
Enhanced lysosomal function is critical for paclitaxel resistance in cancer cells: reversed by artesunate

Zhe Li
Yu-ting Zhu
Fang Lin
Research23 Jul 2020
Acta Pharmacologica Sinica

Volume: 42, P: 624-632
Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models

Meng Yu
Yuhua Fu
Boxun Lu
ResearchOpen Access13 Oct 2017
Cell Research

Volume: 27, P: 1441-1465
Caspase-mediated cleavage of C53/LZAP protein causes abnormal microtubule bundling and rupture of the nuclear envelope

Jianchun Wu
Hai Jiang
Honglin Li
Research12 Mar 2013
Cell Research

Volume: 23, P: 691-704
Artesunate induces necrotic cell death in schwannoma cells

R W Button
F Lin
S Luo
ResearchOpen Access16 Oct 2014
Cell Death & Disease

Volume: 5, P: e1466