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Showing 1–50 of 604 results

Advanced filters: Author: Stephen J. Clark Clear advanced filters

A benchmark of expert-level academic questions to assess AI capabilities

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

Long Phan
Alice Gatti
Davide Scaramuzza
ResearchOpen Access28 Jan 2026
Nature

Volume: 649, P: 1139-1146
The Allende meteorite: evidence for a new cosmothermometer based on Ti³⁺/Ti⁴⁺

Stephen E. Haggerty
Research16 Nov 1978
Nature

Volume: 276, P: 221-225
Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: a Global Burden of Disease Study

Global Burden of Disease estimates show that between 1990 and 2023, the prevalence and burden of drug use disorders, inclusive of amphetamine, cannabis, cocaine and opioid use, have been increasing in high-income countries, particularly in the USA.

Jiseung Kang
Hyeon Jin Kim
Dong Keon Yon
Research16 Jan 2026
Nature Medicine

P: 1-18
A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

Yusuke Yanagi
Yasunobu Yoshikai
Tak W. Mak
Research08 Mar 1984
Nature

Volume: 308, P: 145-149
Natural selection on protein-coding genes in the human genome

Carlos D. Bustamante
Adi Fledel-Alon
Andrew G. Clark
Research20 Oct 2005
Nature

Volume: 437, P: 1153-1157
Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

Stephen M. Hedrick
David I. Cohen
Mark M. Davis
Research08 Mar 1984
Nature

Volume: 308, P: 149-153
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
ResearchOpen Access17 May 2023
Nature

Volume: 617, P: 764-768
Sequence and expression of transcripts of the human T-cell receptor β- chain genes

Yasunobu Yoshikai
Demetri Anatoniou
Tak. W. Mak
Research06 Dec 1984
Nature

Volume: 312, P: 521-524
Toxic Effect of Urea on Plants: Nitrite Toxicity arising from the Use of Urea as a Fertilizer

M. N. COURT
R. C. STEPHEN
J. S. WAID
Research30 Jun 1962
Nature

Volume: 194, P: 1263-1265
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
POSTER SYMPOSIUM: MECHANICAL VENTILATION

Stephen Boros
Ivan Frantz III
Research01 Apr 1987
Pediatric Research

Volume: 21, P: 24-25
Large-scale multi-site study shows no association between musical training and early auditory neural sound encoding

Widely cited studies have claimed that musical training is associated with enhanced neural encoding for sound at early stages of the auditory system. Results from this large-scale multisite study do not support this earlier claim.

Kelly L. Whiteford
Lucas S. Baltzell
Andrew J. Oxenham
ResearchOpen Access08 Aug 2025
Nature Communications

Volume: 16, P: 1-14
Structure of a pertussis toxin–sugar complex as a model for receptor binding

Penelope E. Stein
Amechand Boodhoo
Randy J. Read
Research01 Sept 1994
Nature Structural Biology

Volume: 1, P: 591-596
State dependent ice-sheet resonance under Cenozoic and future climates

Gradual cooling or warming of the atmosphere, combined with strong ocean-driven basal melt, could have led to major changes in the periodicity, phasing, and asymmetry of past ice sheet growth and decay, according to an ensemble of 500-kyr long ice sheet simulations.

Nicholas R. Golledge
Richard H. Levy
Georgia Grant
ResearchOpen Access12 Jan 2026
Communications Earth & Environment

P: 1-11
Whole-genome sequencing reveals host factors underlying critical COVID-19

Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

Athanasios Kousathanas
Erola Pairo-Castineira
J. Kenneth Baillie
ResearchOpen Access07 Mar 2022
Nature

Volume: 607, P: 97-103
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
Nautiloid growth rhythms and lunar dynamics (reply)

STEPHEN M. POMPEA
PETER G. K. KAHN
Research01 May 1979
Nature

Volume: 279, P: 454
Dual Localization of β-Glucuronidase in Endoplasmic Reticulum and in Lysosomes

WILLIAM H. FISHMAN
STEPHEN S. GOLDMAN
RONALD DeLELLIS
Research04 Feb 1967
Nature

Volume: 213, P: 457-460
Solution structure of the ets domain of Fli-1 when bound to DNA

Heng Liang
Xiaohong Mao
Stephen W. Fesik
Research01 Dec 1994
Nature Structural Biology

Volume: 1, P: 871-876
Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5

Kirk L. Clark
Elaine D Halay
Stephen K Burley
Research29 Jul 1993
Nature

Volume: 364, P: 412-420
How the Cerebellum may be Used

STEPHEN BLOMFIELD
DAVID MARR
Research19 Sept 1970
Nature

Volume: 227, P: 1224-1228
CD22 regulates thymus-independent responses and the lifespan of B cells

Kevin L. Otipoby
Kristin B. Andersson
Edward A. Clark
Research26 Dec 1996
Nature

Volume: 384, P: 634-637
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
TFIIS and strand-transfer proteins

DAVID KIPLING
STEPHEN E. KEARSEY
Research10 Oct 1991
Nature

Volume: 353, P: 509
Break for SCIDs

DONALD E. MOSIER
RICHARD J. GULIZIA
DARCY B. WILSON
Research10 Oct 1991
Nature

Volume: 353, P: 509
Positive Allometry of Antlers in the “Irish Elk”, Megaloceros giganteus

STEPHEN JAY GOULD
Research10 Aug 1973
Nature

Volume: 244, P: 375-376
Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

Adrian R. Ferré-D'Amaré
George C. Prendergast
Stephen K. Burley
Research06 May 1993
Nature

Volume: 363, P: 38-45
Magic-angle-spinning NMR shows the aluminosilicate framework of ultramarine to be disordered

Jacek Klinowski
Stuart W. Carr
Paul Barnes
Research05 Nov 1987
Nature

Volume: 330, P: 56-58
Human gene expression first occurs between the four- and eight-cell stages of preimplantation development

Peter Braude
Virginia Bolton
Stephen Moore
Research31 Mar 1988
Nature

Volume: 332, P: 459-461
Complete nucleotide sequence of the AIDS virus, HTLV-III

Lee Ratner
William Haseltine
Flossie Wong-Staal
Research24 Jan 1985
Nature

Volume: 313, P: 277-284
ICAM-1 a ligand for LFA-1-dependent adhesion of B, T and myeloid cells

Malegapuru W. Makgoba
Martin E. Sanders
Stephen Shaw
Research07 Jan 1988
Nature

Volume: 331, P: 86-88
Phyletic Significance of Some Insect Muscle Pherograms

OLIVER W. JOHNSON
WILLIAM P. STEPHEN
Research11 Jul 1964
Nature

Volume: 203, P: 207-209
Magnetic anisotropy in the electron momentum density of iron

Malcolm J. Cooper
Stephen P. Collins
David Laundy
Research12 May 1988
Nature

Volume: 333, P: 151-153
Structure of HIV-1 reverse transcriptase/DNA complex at 7 Å resolution showing active site locations

Edward Arnold
Alfredo Jacobo-Molina
Stephen H. Hughes
Research07 May 1992
Nature

Volume: 357, P: 85-89
Asexual reproduction by oceanic planktotrophic echinoderm larvae

Isidro Bosch
Richard B. Rivkin
Stephen P. Alexander
Research12 Jan 1989
Nature

Volume: 337, P: 169-170
Stereochemistry of phosphoryl group transfer using a chiral [¹⁶O, ¹⁷O, ¹⁸O] stereochemical course of alkaline phosphatase

STEPHEN R. JONES
L. ALLEN KINDMAN
JEREMY R. KNOWLES
Research12 Oct 1978
Nature

Volume: 275, P: 564-565
Upper Limits on Galactic Cosmic Ray Antiproton Intensities

S. N. MILFORD
STEPHEN ROSEN
Research06 Feb 1965
Nature

Volume: 205, P: 582-584
Population genomics of domestic and wild yeasts

David Carter
Gianni Liti
Edward Louis
ResearchOpen Access20 Jun 2008
Nature Precedings

P: 1
Estimation of genome-wide coupling in rattlesnake hybrids provides insight into the process of speciation and its progress

Genomic coupling theory predicts that speciation progress involves the buildup of genomic associations that manifest in aggregate barriers to gene flow. This study develops approaches to quantify genomic coupling and applies them to a rattlesnake hybrid zone.

Yannick Z. Francioli
Justin M. Bernstein
Todd A. Castoe
ResearchOpen Access21 Nov 2025
Nature Communications

Volume: 16, P: 1-16
Regulatory intramolecular association in a tyrosine kinase of the Tec family

Amy Hamilton Andreotti
Stephen C. Bunnell
Stuart L. Schreiber
Research02 Jan 1997
Nature

Volume: 385, P: 93-97
Human Genome Variation 2006: emerging views on structural variation and large-scale SNP analysis

The eighth annual Human Genome Variation Meeting was held in September 2006 in the Hong Kong Special Administrative Region, China. The meeting highlighted recent advances in characterization of genetic variation, including genome-wide association studies and structural variation.

Gonçalo Abecasis
Paul Kwong-Hang Tam
Anthony J Brookes
News & Views01 Feb 2007
Nature Genetics

Volume: 39, P: 153-155
Structural similarity between the p17 matrix protein of HIV-1 and interferon-γ

Stephen Matthews
Paul Barlow
Iain Campbell
Research25 Aug 1994
Nature

Volume: 370, P: 666-668
The Effects of Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor on in Vitro Cord Blood Granulocyte Function

Robert W Frenck Jr
E Stephen Buescher
Saroj Vadhan-Raj
Research01 Jul 1989
Pediatric Research

Volume: 26, P: 43-48
The Ash Seed Screw

A. STEPHEN WILSON
Research30 Mar 1876
Nature

Volume: 13, P: 428
Cholinergic supersensitivity of the iris in primary open angle glaucoma. A clinical study

Kerry Jordan
Stephen R Perry
Richard N Downes
Research01 May 1988
Eye

Volume: 2, P: 233-237
Striding on water

STEPHEN J. CLARK
Research13 Jun 1991
Nature

Volume: 351, P: 527
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

COVID-19 can be associated with neurological complications. Here the authors show that markers of brain injury, but not immune markers, are elevated in the blood of patients with COVID-19 both early and months after SARS-CoV-2 infection, particularly in those with brain dysfunction or neurological diagnoses.

Benedict D. Michael
Cordelia Dunai
David K. Menon
ResearchOpen Access22 Dec 2023
Nature Communications

Volume: 14, P: 1-15
Climatic effects of Volcanic eruptions

MICHAEL R. RAMPINO
RICHARD B. STOTHERS
STEPHEN SELF
Research24 Jan 1985
Nature

Volume: 313, P: 272
Author Correction: GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Erola Pairo-Castineira
Konrad Rawlik
J. Kenneth Baillie
Amendments and CorrectionsOpen Access11 Jul 2023
Nature

Volume: 619, P: E61
T-cell colonies recognize antigen in association with specific epitopes on Ia molecules

Robert B. Clark
Joe Chiba
Ethan M. Shevach
Research04 Feb 1982
Nature

Volume: 295, P: 412-414

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