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A selected group of intermediate-redshift galaxies appear similar to primeval galaxies. Analysing spectra of these nearer analogues for chemical abundances and ionization levels gives an improved understanding of galaxies that are too faint to study well.

Observation of the emission line of doubly ionized oxygen at a redshift of 9.1096 reveals that star formation began at a redshift of about 15, around 250 million years after the Big Bang.

The authors from the ALICE collaboration identify multiple species of mesons and baryons and measure the anisotropic flow with non-flow removal techniques in pp and p-Pb collisions at the LHC, identifying the hallmark of quark flow associated with an expanding quark-gluon plasma.

Understanding collective behaviour is an important aspect of managing the pandemic response. Here the authors show in a large global study that participants that reported identifying more strongly with their nation reported greater engagement in public health behaviours and support for public health policies in the context of the pandemic.

Inertial confinement fusion experiments in a direct-drive configuration report more energy produced in deuterium–tritium fusion reactions than the amount of energy in the central part of the plasma created by laser irradiation of the fuel capsule.

Hydro-equivalent scaling of recent direct-drive inertial confinement fusion implosions shows that a burning plasma can be achieved with a higher laser energy.

In burning plasma, alpha particles from fusion reactions are the dominant source of heating. The design choices that resulted in reaching this state in experiments at the National Ignition Facility are reported.

A demonstration of the ability to control the flow of laser energy in a dense plasma by tuning the colour of multiple laser beams injected into it could be useful in the development of laser-driven fusion.

A JWST/MIRI spectrum of an early quasar in the mid-infrared indicates that J1120+0641 had a mature feeding structure 760 Myr after the Big Bang. This finding suggests that supermassive black holes and their torii build up surprisingly quickly.

The transforming growth factor-β (TGFβ) ligands have important functions in cancer. However, it is now becoming apparent that many of the other TGFβ superfamily members (bone morphogenetic proteins (BMPs), activins, NODAL, and growth and differentiation factors (GDFs)) have crucial roles in tumorigenesis and metastasis; these are the focus of this Review.

A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants.

The most up-to-date combination of results on the properties of the Higgs boson is reported, which indicate that its properties are consistent with the standard model predictions, within the precision achieved to date.

Recent improvements in the indirect-drive inertial confinement fusion experiments include the achievement of burning plasma state. Here the authors report the scaling of neutron yield in a burning plasma of Deuterium-Tritium fusion reaction by including the mode-2 asymmetry.

The LHCb experiment at CERN has observed significant asymmetries between the decay rates of the beauty baryon and its CP-conjugated antibaryon, thus demonstrating CP violation in baryon decays.

Whole-genome sequencing and phylogenetic analysis of nearly 400 esophageal adenocarcinoma samples suggest a model of rapid subclone spreading from the primary tumor to multiple metastatic sites, which the authors term ‘clonal diaspora’.

An antimatter hypernucleus formed by an anti-lambda hadron, an antiproton and two antineutrons was observed through its two-body decay after production in ultrarelativistic heavy-ion collisions.

Openshaw and colleagues find myeloid inflammation and complement activation signatures in patients with long COVID who were previously hospitalized.

Using intergenic regions and coalescent methods to analyse the genomes of 363 bird species, the authors present a well-supported tree confirming that Neoaves experienced rapid radiation at or near the Cretaceous–Palaeogene boundary.

Comparative study of 81 genomes of parasitic and non-parasitic worms identifies gene family births and expanded gene families at key nodes in the phylogeny that are relevant to parasitism and proteins historically targeted for drug development.

In this work, charge recombination and losses in inverted solar cells with dual organic cations interfacial passivation are quantified by mapping physical parameters obtained via continuous wave and time resolved photoluminescence imaging techniques.

Combined analysis of proton-proton collision data from the Large Hadron Collider at CERN by the CMS and LHCb collaborations leads to the observation of the extremely rare decay of the strange B meson into muons; the result is compatible with the standard model of particle physics, and does not show any signs of new physics, such as supersymmetry.

Data from over 700,000 individuals reveal the identity of 83 sequence variants that affect human height, implicating new candidate genes and pathways as being involved in growth.

The contribution of intra-tumour heterogeneity is increasingly associated with resistance to therapy. Here, the authors use genomic analyses to study heterogeneity in colorectal cancer and perform in-depth reconstruction of heterogeneity in one sample.

This protocol combines in situ chromosome conformation capture with labeling of nascent DNA with the synthetic nucleoside 4-thio-thymidine to generate genome-wide contact probability maps within and across sister chromatids in mammalian cells.

The 21-cm absorption profile is detected in the sky-averaged radio spectrum, but is much stronger than predicted, suggesting that the primordial gas might have been cooler than predicted.

The gluonic gravitational form factor of the proton was determined using various models, and these analyses showed that the mass radius of the proton was smaller than the electric charge radius.

Genomic and molecular analyses of Clunio marinus timing strains suggest that modulation of alternative splicing of Ca2+/calmodulin-dependent kinase II represents a mechanism for evolutionary adaptation of circadian timing.

Exome-wide analysis identifies rare and low-frequency coding variants associated with body mass index. Gene-based meta-analysis and functional studies implicate 13 genes, eight of which are novel, and neuronal pathways as factors in human obesity.

A burning plasma, a critical step towards self-sustaining fusion, is achieved at the US National Ignition Facility, with a subset of experiments demonstrating fusion self-heating beyond radiation and conduction losses.

Observations of SN 2021yfj reveal that its progenitor is a massive star stripped down to its O/Si/S core, which remarkably continued to expel vast quantities of silicon-, sulfur-, and argon-rich material before the explosion, informing us that current theories for how stars evolve are too narrow.

This paper proposes a framework to assess systemic risks that compound and cascade within and between systems. This emphasizes political economy and transformations, as well as trans-disciplinarity and diverse participation, evidence and methods.

Altermagnets recently emerged as a new class of magnetic materials, arising from specific spin crystal symmetries. This paper studies a layered triangular lattice altermagnet, cobalt-intercalated NbSe2, using scanning tunneling microscopy and spectroscopy.

The clonal architecture of colon cancer and the relevance of tumor cell subpopulations for clonal outgrowth are poorly understood. Here, the authors describe the clonal architecture and dynamics in human colon cancer by using a multicolor lineage tracing approach in colon cancer xenografts.