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Maier, Raja Beharelle et al. provide a computational model of the decision process that quantifies the temporal dynamics of weighing different attributes. Their time-varying drift diffusion model reveals latent individual differences in decision-making.

Demonstration of ballistic conduction and spin polarization of edge state currents in two dimensional topological insulators remains a challenge. Here, Muraniet al. report a direct signature of ballistic one dimensional transport along the topological surfaces of a bismuth nanowire connected to superconducting electrodes.

The Candidate Phyla Radiation (CPR) constitutes a large group of bacterial lineages with small cell sizes and limited biosynthetic capabilities. Here, Moreira et al. study the biology and genome of Vampirococcus lugosii, an epibiotic parasite of other bacteria, supporting parasitism as a common lifestyle of CPR bacteria.

The key challenge in CO₂ methanation is achieving efficient CH₄ production at lower temperatures. Here, the authors introduce a Ru catalyst supported on layered Na₂Ti₃O₇, which stabilizes low-valence Ru and facilitates CO₂ activation at low temperatures.

There is emerging interest in photodetectors in the mid-infrared driven by increasing need to monitor the environment for security and healthcare purposes. Sassiet al. show a thermal photodetector, based on the coupling between graphene and a pyroelectric crystal, which shows high temperature sensitivity.

Previously documented record values of the fusion triple product in the stellarator Wendelstein 7-X are shown to be evidence for reduced neoclassical energy transport in this optimized device.

Mechanically interlocked architectures inspired the fabrication of numerous molecular systems, but the topological design of such architectures has not been fully explored from the nano- to the macroscopic scale. Here, the authors propose a MOFaxane, comprised of long chain molecules penetrating a microcrystal of metal– organic framework.

Conventional wet chemistry method represents an inefficient way for bulk crystal synthesis. Here, the authors report a universal approach using electrical and mechanical field-assisted sintering technique to generate halide perovskites from solid precursors into large bulk crystal within minutes.

Using high-throughput detection of prey DNA from spiders in a grassland ecosystem, the authors reconstruct interaction networks between 50 spider species and 974 prey species and strains, documenting shifting seasonal dynamics.

The TRPV3 ion channel has been reported to contribute to thermosensation. Here, the authors use electrophysiology and a thermal gradient ring method to show a transmembrane protein TMEM79 negatively regulates TRPV3-mediate currents and changed thermal preference.

Time-resolved cryo-EM captured transient intermediates during E. coli RNAP promoter melting, revealing conformational changes affecting stepwise transcription bubble opening. Results inform how DNA sequence controls bacterial transcription initiation.

Genetic variants in ionotropic glutamate receptors have been implicated in neurodevelopmental disorders. Here, the authors report heterozygous de novo mutations in the GRIA2 gene in 28 individuals with intellectual disability and neurodevelopmental abnormalities associated with reduced Ca²⁺ transport and AMPAR currents.”

The parallel cryo electron tomography (PACE-tomo) method increases the throughput on in situ samples by parallelizing acquisition. It maximizes the usable sample area on individual lamellae without compromising data quality.

Spider silk is of interest in material science research. Here the authors show that the tight binding of a spider silk protein domain relies on the amino acid methionine, which is abundant in the domain core where it facilitates dynamic shape adaption of the binding interface.

Plasma created in laboratory are useful to understand the properties of atmospheric and space plasma. Here the authors report a laboratory plasma experiment in a dipole magnetic field to show the excitation of chirping whistler waves, i.e. chorus emission.

Present Li-ion batteries for portable electronics are based on inorganic electrodes made through non-ecological processes. Sustainable conjugated dicarboxylate organic salt anodes showing advantageous reversible capacities and thermal stability are now reported.

Hydrogen generated from splitting water using a catalyst and solar energy is an ideal energy source. A polymeric carbon nitride photocatalyst that is thermally and chemically stable is now shown to produce hydrogen from water even in the absence of noble metal catalysts.

PLXDC2 marks hematopoietic stem cells in mouse and human cord blood, enabling reliable identification with reporter mice and an antibody, and serving as a tool for imaging and transplantation studies.

Surface strain can be used in gas phase catalysis and electrocatalysis to control the binding energies of adsorbates on active sites, but in situ or operando strain measurements can be challenging. Coherent diffraction now allows strain inside individual Pt nanoparticles to be mapped and quantified under electrochemical control.

High-pressure technology is key for exploring condensed matter physics and planetary science, but determining the pressure generated by static compression varies across different disciplines. Here, a systematic way to achieve mutual consistency under extreme pressure conditions is established

The thermosensory system across insects and mammals has shared principles of neuronal wiring and encoding. In this Review, Carta, Vestergaard and Poulet discuss how the nervous systems of insects and mammals process the thermal information that underlies thermal perception.

A multicomponent gas of ytterbium atoms accommodates more entropy in its spin degrees of freedom than does its two-component analogue, leading to a lower effective temperature, and an easy route for cooling ultracold fermions towards a Mott-insulating state.

Guard cells define microscopic stomatal pores for CO₂ uptake and water loss. Characterization of the extracellular metabolome revealed sugars as ‘mesophyll messengers’ from the leaf interior that enhance stomatal opening via regulation of the guard-cell H⁺-ATPase and anion channels.

By using an ultrastable oscillator based on a cryogenic Si cavity, the fractional instability of two Sr optical lattice clocks at 1 s reaches 4.8 × 10⁻¹⁷ and 3.5 × 10⁻¹⁷ through anti-synchronous and synchronous comparisons, respectively.

The consumption of fermentable carbohydrates, or fibre, is associated with weight loss. Here the authors show that the metabolite acetate, created by fermentation of fibre in the mouse colon, is taken up into the brain where it induces appetite-suppressing neuronal activity in the hypothalamus.

Few non-copper catalysts have been observed to produce appreciable amounts of propane—a useful fuel—by electrochemical reduction of CO₂. New research shows that ionomer-coated imidazolium-functionalized Mo₃P nanoparticles produce propane with high activity and selectivity.

In aged mice, inhibition of prostaglandin E₂ (PGE₂) signalling through its receptor EP2 improves cellular bioenergetics, reduces inflammatory responses and restores hippocampal plasticity to youthful levels, resulting in an improvement in spatial memory and cognition.

Hoshino et al., engineer a human virus receptor, hACE2, and demonstrate its potential for overcoming SARS-CoV-2 mutations that otherwise hinder therapeutic interventions. Overall, the data provide insights in to the therapeutic potential of engineered receptors.

The specific high-sensitivity enzymatic reporter unlocking (SHERLOCK) assay detected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA with high sensitivity and specificity in hundreds of nasopharyngeal and throat swab samples collected at Siriraj Hospital in Thailand.

Understanding the chemistry of perovskite precursor solutions enables improved film optoelectronic properties, allowing the fabrication of multijunction solar cells achieving power conversion efficiencies beyond the radiative limit of single-junction cells.

Although the precise function of Tryptophan rich antigen multi-gene family (TRAgs) proteins is not known in any Plasmodium species several members of the P. vivax TRAg family have been reported to have red blood cell binding properties. Here, Kundu and Naskar et al. provide the X-ray crystallography structure of a P. vivax TRAg domain of PVP01_0000100. Structural and biochemical assays suggest a lipid binding function for a pan-Plasmodium multi-gene family.

Methods for coherently transferring quantum states are needed in order to develop larger scale quantum devices. Here the authors implement an adiabatic transfer protocol in a triple quantum dot and show that dephasing noise can accelerate the process while maintaining the coherence of the transferred state.

While measurement of an electron spin commonly destroys it, the quantum non-demolition measurement implemented here for an electron spin qubit in a semiconductor quantum dot preserves the measured spin and allows for exponential suppression of readout errors by repeated measurements.

Long-term use of opioids can lead to a paradoxical increase in pain sensitivity. Here, Hayashi et al. link activation of potassium channels on microglia with morphine-induced hyperalgesia and anti-nociceptive tolerance in mice.

Plants sense volatiles emitted by injured neighboring plants and elicit defense responses to external threats. Here, the authors show that Arabidopsis leaves uptake two green leaf volatiles via stomata and trigger cytosolic Ca²⁺ defense signaling.

The mechanism of amorphous-amorphous transitions is highly debated. Here, the authors use molecular dynamics simulations to reveal transitions via nucleation-growth or spinodal decomposition, resembling a thermodynamic phase transition but influenced by mechanics.