Macrophages secrete diverse signaling proteins critical for intercellular communication and immune responses, processes tightly regulated by post-translational modifications (PTMs). Here, the authors present a PTM-based secretome profiling (PBSP) method, which allows exploring PTM roles in protein secretion, offering insights into PTMs’ regulatory functions in cell-cell communication.
- Wenjie Lu
- Yanling Zhang
- Wei Qin
