Fragile X mental retardation is caused by mutations in the FMRP gene. Now, Xinyu Zhao and her colleagues show that deletion of Fmrp specifically in adult neural progenitor cells is sufficient to induce learning deficits in mice, whereas restoration of Fmrp only in neural progenitor cells in Fmrp-deficient mice restores learning.
- Weixiang Guo
- Andrea M Allan
- Xinyu Zhao
