Nature Search

Natural variation in Ghd7 is an important regulator of heading date and yield potential in rice

Weiya Xue
Yongzhong Xing
Qifa Zhang
Research04 May 2008
Nature Genetics

Volume: 40, P: 761-767
Characterization of mouse melanocytes reveals ultrastructural and immunological insights into the inner ear function

Electron microscopy and single-cell RNA sequencing analysis help distinguish melanocytes and macrophages in the inner ear, which are often misidentified.

Jing Cai
Lei Xu
Haibo Wang
ResearchOpen Access26 Jan 2026
Communications Biology

P: 1-18
Integrated predictive model for visceral pleural invasion in small NSCLC with high clinical utility

Shuyi Yang
Ying Wei
Fei Shan
ResearchOpen Access29 Jan 2026
npj Precision Oncology

P: 1-13
Correction: Comprehensive analysis of the PLXNA3 gene on prognosis and immune characteristics in breast cancer

Wen Sun
Yifan Xu
Wenbin Zhou
Amendments and CorrectionsOpen Access07 Jan 2026
Scientific Reports

Volume: 16, P: 1-2
Arctic Sea Route access reshapes global shipping carbon emissions

Arctic Sea Route access will raise global shipping CO₂ by 8.2% by 2100 and worsen regional inequities. IMO 2023 strategy and Green Corridor plans fall short; only a net-zero pathway with stricter fuels and phased rollout eliminates ASR emissions.

Pengjun Zhao
Yunlin Li
Weiya Kong
ResearchOpen Access29 Sept 2025
Nature Communications

Volume: 16, P: 1-13
TaTCP6 is required for efficient and balanced utilization of nitrate and phosphorus in wheat

A nitrate-induced transcription factor TaTCP6 is identified as a central regulator for the efficient and balanced utilization of nitrate and phosphorus, and a moderate increase in its expression promotes wheat yield.

Bin Liu
Weiya Xu
Jiewen Xing
ResearchOpen Access16 Feb 2025
Nature Communications

Volume: 16, P: 1-19
Comprehensive analysis of the PLXNA3 gene on prognosis and immune characteristics in breast cancer

Wen Sun
Yifan Xu
Wenbin Zhou
ResearchOpen Access04 Aug 2025
Scientific Reports

Volume: 15, P: 1-10
Scaling DNA synthesis with a microchip-based massively parallel synthesis system

A microchip-based DNA synthesis method enables scalable production of complex DNA constructs.

Xiandi Zhang
Xiang’er Jiang
Yue Shen
Research01 Oct 2025
Nature Biotechnology

P: 1-7
Author Correction: Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes

Chunlong Xu
Yingsi Zhou
Hui Yang
Amendments and Corrections02 Jan 2022
Nature Methods

Volume: 19, P: 255
Remote on–off switching of protein activity by intrinsically disordered region

Here the authors uncover how a floppy tail in a protein acts as a remote switch, flipping activity on or off by tweaking internal motion, which reveals a powerful new way proteins regulate themselves without direct contact.

Tuo Ji
Piao Ge
Chengdong Huang
Research04 Jun 2025
Nature Structural & Molecular Biology

Volume: 32, P: 2088-2098
Engineered CRISPR-OsCas12f1 and RhCas12f1 with robust activities and expanded target range for genome editing

Cas12f proteins are small and sought after for therapeutic applications. Here the authors report six bacterial Cas12f1 proteins with nuclease activity in mammalian cells, perform sgRNA and protein engineering to generate variants with enhanced editing and broader PAMs, apply an inducible version in vivo.

Xiangfeng Kong
Hainan Zhang
Hui Yang
ResearchOpen Access11 Apr 2023
Nature Communications

Volume: 14, P: 1-13
The dynamic triage interplay of Hsp90 with its chaperone cycle and client binding

Here the authors reveal how ATP binding, hydrolysis, and client interactions dynamically tune the E. coli homolog of Hsp90, HtpG, providing atomic-level insights into its chaperone cycle and functional mechanism.

Xiaozhan Qu
Simin Wang
Chengdong Huang
ResearchOpen Access11 Dec 2024
Nature Communications

Volume: 15, P: 1-12
Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes

This work describes the identification of Cas13 proteins from two families by mining public metagenomic data. The newly identified Cas13X.1 shows efficient target knockdown and can be used to degrade SARS-CoV-2 and H1N1 genomes. In addition, the truncated Cas13X.1 offers an advantage in generating mini-RNA base editors.

Chunlong Xu
Yingsi Zhou
Hui Yang
Research03 May 2021
Nature Methods

Volume: 18, P: 499-506
Phase-separated CCER1 coordinates the histone-to-protamine transition and male fertility

Here the authors reveal that phase‐separated nuclear CCER1 condensates are required for male fertility by mediating chromatin condensation and histone epigenetic modification, while loss‐of‐function variants of human CCER1 are pathogenic in patients with nonobstructive azoospermia (NOA).

Dongdong Qin
Yayun Gu
Zhibin Hu
ResearchOpen Access11 Dec 2023
Nature Communications

Volume: 14, P: 1-17
Structural basis for the dynamic chaperoning of disordered clients by Hsp90

Here, using nuclear magnetic resonance spectroscopy, the authors delineate how the molecular chaperone Hsp90, in its open state, uses its two middle domains to synergistically capture a disordered client in a highly dynamic manner, forming a bipartite complex.

Xiaozhan Qu
Shuo Zhao
Chengdong Huang
Research18 Jun 2024
Nature Structural & Molecular Biology

Volume: 31, P: 1482-1491
The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis

Phosphorylation of INSIG1 and INSIG2 by PCK1 leads to a reduction in the binding of sterols, the activation of SREBP1 and SREBP2 and the downstream transcription of lipogenesis-associated genes that promote tumour growth.

Daqian Xu
Zheng Wang
Zhimin Lu
Research08 Apr 2020
Nature

Volume: 580, P: 530-535
Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance

The maintenance of cell polarity depends on adhesion complexes that tether to the cytoskeleton. Here the authors show the dynamic nature of E-cadherin–Ankyrin-G complex formation and investigate its functional role in epithelial cell polarity maintenance.

Chao Kong
Xiaozhan Qu
Chao Wang
ResearchOpen Access27 Oct 2023
Nature Communications

Volume: 14, P: 1-15
Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation

Human ribonuclease 1 (hRNase 1) regulates innate immunity, hemostasis and RNA clearance. Here, the authors report an alternative function of hRNase 1 as a secretory ligand of Eph receptor EphA4 to enhance breast cancer stemness and promote breast tumour initiation.

Heng-Huan Lee
Ying-Nai Wang
Mien-Chie Hung
ResearchOpen Access13 May 2021
Nature Communications

Volume: 12, P: 1-18
Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition

Binhua P. Zhou
Jiong Deng
Mien-Chie Hung
Research26 Sept 2004
Nature Cell Biology

Volume: 6, P: 931-940
DOC-2/hDab-2 inhibits ILK activity and induces anoikis in breast cancer cells through an Akt-independent pathway

Shao-Chun Wang
Keishi Makino
Mien-Chie Hung
Research25 Oct 2001
Oncogene

Volume: 20, P: 6960-6964
Modeling mammalian hibernation to improve organ cold preservation: Using the intestine as an example

Weiya He
Ziqing He
Ji Dong
Correspondence28 Jul 2025
Cell Research

Volume: 35, P: 691-694
Blood unconjugated bilirubin and tacrolimus are negative predictors of specific cellular immunity in kidney transplant recipients after SAR-CoV-2 inactivated vaccination

Lei Zhang
Jiaqing Yang
Tianxing Ji
ResearchOpen Access04 May 2023
Scientific Reports

Volume: 13, P: 1-12
Combining single-cell RNA sequencing and population-based studies reveals hand osteoarthritis-associated chondrocyte subpopulations and pathways

Hui Li
Xiaofeng Jiang
Guanghua Lei
ResearchOpen Access02 Nov 2023
Bone Research

Volume: 11, P: 1-13
Efficient Inhibition of Hepatitis B Virus Infection by a preS1-binding Peptide

Xiaoli Ye
Ming Zhou
Youhua Xie
ResearchOpen Access07 Jul 2016
Scientific Reports

Volume: 6, P: 1-11
Simple and fast fabrication of single crystal VO₂ microtube arrays

Vanadium dioxide is well known to display a metal-insulator transition, making it an attractive option for functional devices. Here, the growth of single crystal VO₂ microtube arrays is achieved via a thermal oxidation process that is faster and simpler than many existing fabrication technologies.

Chunwang Zhao
Shuxiang Ma
Yongming Xing
ResearchOpen Access15 May 2020
Communications Materials

Volume: 1, P: 1-9
Structural insights into selective inhibition of leishmanial GDP-mannose pyrophosphorylase

Hang Li
Tuo Ji
Chengdong Huang
CorrespondenceOpen Access30 Aug 2022
Cell Discovery

Volume: 8, P: 1-4

Search

Natural variation in Ghd7 is an important regulator of heading date and yield potential in rice

Characterization of mouse melanocytes reveals ultrastructural and immunological insights into the inner ear function

Integrated predictive model for visceral pleural invasion in small NSCLC with high clinical utility

Correction: Comprehensive analysis of the PLXNA3 gene on prognosis and immune characteristics in breast cancer

Arctic Sea Route access reshapes global shipping carbon emissions

TaTCP6 is required for efficient and balanced utilization of nitrate and phosphorus in wheat

Comprehensive analysis of the PLXNA3 gene on prognosis and immune characteristics in breast cancer

Scaling DNA synthesis with a microchip-based massively parallel synthesis system

Author Correction: Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes

Remote on–off switching of protein activity by intrinsically disordered region

Engineered CRISPR-OsCas12f1 and RhCas12f1 with robust activities and expanded target range for genome editing

The dynamic triage interplay of Hsp90 with its chaperone cycle and client binding

Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes

Phase-separated CCER1 coordinates the histone-to-protamine transition and male fertility

Structural basis for the dynamic chaperoning of disordered clients by Hsp90

The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis

Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance

Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation

Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition

DOC-2/hDab-2 inhibits ILK activity and induces anoikis in breast cancer cells through an Akt-independent pathway

Modeling mammalian hibernation to improve organ cold preservation: Using the intestine as an example

Blood unconjugated bilirubin and tacrolimus are negative predictors of specific cellular immunity in kidney transplant recipients after SAR-CoV-2 inactivated vaccination

Combining single-cell RNA sequencing and population-based studies reveals hand osteoarthritis-associated chondrocyte subpopulations and pathways

Efficient Inhibition of Hepatitis B Virus Infection by a preS1-binding Peptide

Simple and fast fabrication of single crystal VO₂ microtube arrays

Structural insights into selective inhibition of leishmanial GDP-mannose pyrophosphorylase

Search

Quick links

Search

Filter By:

Search

Quick links