Nature Search

Low reactogenicity and high tumour antigen expression from mRNA-LNPs with membrane-destabilizing zwitterionic lipids

Incorporating membrane-destabilizing zwitterionic lipids into commercially available LNPs boosts mRNA expression in antigen-presenting cells within lymph nodes, enhancing cytotoxic T cell activation, and dampens reactogenicity in mice.

Yu Zhao
Ruoxin Li
Shaoyi Jiang
Research18 Dec 2025
Nature Biomedical Engineering

P: 1-15
A subnanolitre tetherless optoelectronic microsystem for chronic neural recording in awake mice

A neural implant with a subnanolitre-volume can provide year-long in vivo recordings in awake mice.

Sunwoo Lee
Shahaboddin Ghajari
Alyosha C. Molnar
ResearchOpen Access03 Nov 2025
Nature Electronics

Volume: 8, P: 1259-1271
Extracellular vesicles incorporating retrovirus-like capsids for the enhanced packaging and systemic delivery of mRNA into neurons

The delivery of mRNAs into neurons at inflammatory sites in vivo can be enhanced by engineering leucocytes to produce extracellular vesicles incorporating mRNA-packaging retrovirus-like capsids.

Wenchao Gu
Sijin Luozhong
Shaoyi Jiang
Research19 Feb 2024
Nature Biomedical Engineering

Volume: 8, P: 415-426
Study on calculation of nonlimit passive earth pressure of unsaturated soil behind retaining wall

Yaxin Zhang
Wenchao Gu
Shiyuan Huang
ResearchOpen Access20 May 2025
Scientific Reports

Volume: 15, P: 1-12
Development and validation of a motivation scale for deep vein thrombosis prophylaxis in postdischarge hip and knee arthroplasty patients

Feng Fu
Xiurui Deng
Yinglan Li
ResearchOpen Access11 Dec 2025
Scientific Reports

Volume: 16, P: 1-16
Effect of external infusion connection devices replacement frequency on catheter related bloodstream infection

Wenchao Wang
Yuqing Wang
Ying Gu
ResearchOpen Access27 Jan 2025
Scientific Reports

Volume: 15, P: 1-8
Strain-restricted transfer of ferromagnetic electrodes for constructing reproducibly superior-quality spintronic devices

To optimize the interfacial quality and electrode magnetism in spintronic devices, the authors develop an electrode transfer technique that can greatly improve device interfacial quality, performance and reproducibility, universal to various spacers.

Lidan Guo
Xianrong Gu
Xiangnan Sun
ResearchOpen Access29 Jan 2024
Nature Communications

Volume: 15, P: 1-10
Metabolomic and transcriptomic profiling of HNSCC identifies AMIGO2 as a therapeutic target modulating tumor microenvironment

Gan Liu
Xinfeng Yao
Zongcheng Yang
ResearchOpen Access18 Nov 2025
npj Precision Oncology

Volume: 9, P: 1-18
Leukocyte CH25H is a potential diagnostic and prognostic marker for lung adenocarcinoma

Jun Zhang
Lidong Xu
Daoyun Zhang
ResearchOpen Access23 Dec 2022
Scientific Reports

Volume: 12, P: 1-9
Ultra-conformal skin electrodes with synergistically enhanced conductivity for long-time and low-motion artifact epidermal electrophysiology

Novel dry electrodes with enhanced mechano-electrical stability and conformability are attractive for long-time electrophysiological signal monitoring. Here, the authors report polymer-covered CVD-grown graphene with enhanced optoelectronic performance for biopotential monitoring.

Yan Zhao
Song Zhang
Nan Liu
ResearchOpen Access12 Aug 2021
Nature Communications

Volume: 12, P: 1-12
Pan-neuronal calcium imaging with cellular resolution in freely swimming zebrafish

A tracking microscope for imaging neuronal activity at single-cell resolution in freely swimming zebrafish larvae is described. This technology allows functional imaging during behaviors that have previously been inaccessible to real-time analysis.

Dal Hyung Kim
Jungsoo Kim
Drew N Robson
Research11 Sept 2017
Nature Methods

Volume: 14, P: 1107-1114
Loss of HES1 expression is associated with extracellular matrix remodeling and tumor immune suppression in KRAS mutant colon adenocarcinomas

Lei Wang
Wenchao Gu
Lan Zhou
ResearchOpen Access25 Sept 2023
Scientific Reports

Volume: 13, P: 1-13
NRF2-mediated persistent adaptation of oesophageal adenocarcinoma cells to HER2 inhibition

Wei Zhang
Jiaqing Lang
Cathy Tournier
ResearchOpen Access05 Jun 2025
Oncogene

Volume: 44, P: 2929-2941
Single irrigation at the four-leaf stage in the spring optimizes winter wheat water consumption characteristics and water use efficiency

Xiaoyuan Bao
Xuejing Liu
Wenchao Zhen
ResearchOpen Access22 Aug 2022
Scientific Reports

Volume: 12, P: 1-14
The microRNA-10a/ID3/RUNX2 axis modulates the development of Ossification of Posterior Longitudinal Ligament

Chen Xu
Hao Zhang
Wen Yuan
ResearchOpen Access15 Jun 2018
Scientific Reports

Volume: 8, P: 1-13
Ubiquitin-specific protease 7 regulates myocardial ischemia/reperfusion injury by stabilizing Keap1

Qiong Xu
Mingke Liu
Ningning Liu
ResearchOpen Access16 Jun 2022
Cell Death Discovery

Volume: 8, P: 1-10
Three-dimensional entanglement on a silicon chip

Liangliang Lu
Lijun Xia
Xiao-Song Ma
ResearchOpen Access26 Mar 2020
npj Quantum Information

Volume: 6, P: 1-9

Search

Low reactogenicity and high tumour antigen expression from mRNA-LNPs with membrane-destabilizing zwitterionic lipids

A subnanolitre tetherless optoelectronic microsystem for chronic neural recording in awake mice

Extracellular vesicles incorporating retrovirus-like capsids for the enhanced packaging and systemic delivery of mRNA into neurons

Study on calculation of nonlimit passive earth pressure of unsaturated soil behind retaining wall

Development and validation of a motivation scale for deep vein thrombosis prophylaxis in postdischarge hip and knee arthroplasty patients

Effect of external infusion connection devices replacement frequency on catheter related bloodstream infection

Strain-restricted transfer of ferromagnetic electrodes for constructing reproducibly superior-quality spintronic devices

Metabolomic and transcriptomic profiling of HNSCC identifies AMIGO2 as a therapeutic target modulating tumor microenvironment

Leukocyte CH25H is a potential diagnostic and prognostic marker for lung adenocarcinoma

Ultra-conformal skin electrodes with synergistically enhanced conductivity for long-time and low-motion artifact epidermal electrophysiology

Pan-neuronal calcium imaging with cellular resolution in freely swimming zebrafish

Loss of HES1 expression is associated with extracellular matrix remodeling and tumor immune suppression in KRAS mutant colon adenocarcinomas

NRF2-mediated persistent adaptation of oesophageal adenocarcinoma cells to HER2 inhibition

Single irrigation at the four-leaf stage in the spring optimizes winter wheat water consumption characteristics and water use efficiency

The microRNA-10a/ID3/RUNX2 axis modulates the development of Ossification of Posterior Longitudinal Ligament

Ubiquitin-specific protease 7 regulates myocardial ischemia/reperfusion injury by stabilizing Keap1

Three-dimensional entanglement on a silicon chip

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