Nature Search

Global, regional and national burden of ischemic heart disease attributable to suboptimal diet, 1990–2023: a Global Burden of Disease study

Global Burden of Disease analysis found that in 2023, suboptimal diet was estimated to be responsible for 4 million deaths and 97 million morbidity burdens from ischemic heart disease.

Sooji Lee
Hayeon Lee
Dong Keon Yon
Research30 Mar 2026
Nature Medicine

P: 1-25
Stringent tests of spin-up theories posed by a millisecond pulsar with an extreme spin-down rate

Millisecond pulsar PSR J0435+3233, with a spin-down rate that is 100 times higher than those of other millisecond pulsars, occupies a unique position on the P–Ṗ diagram. This pulsar challenges classical recycling models and constrains spin-up theories.

Qingdong Wu
Na Wang
Jiarui Niu
Research08 Apr 2026
Nature Astronomy

P: 1-9
Analysis of nozzle for the external casing perforation tool and experimental study on AWJ

Xianke Ren
Wenming Zhu
Jinjian Yao
ResearchOpen Access09 Jan 2026
Scientific Reports

Volume: 16, P: 1-17
Modular total syntheses of trans-clerodanes and sesquiterpene (hydro)quinones via tail-to-head cyclization and reductive coupling strategies

trans-Clerodanes and sesquiterpene (hydro)quinones are different types of natural products featuring the same trans-decalin core. Here, the authors report a modular synthetic route to this family by tail-to-head cyclization and reductive coupling strategies.

Wenming Zhu
Qishuang Yin
Ming Yang
ResearchOpen Access04 Nov 2022
Nature Communications

Volume: 13, P: 1-7
The novel role of GADD45A in the etiology of autism: modulating neuronal excitability via TET1/R-loop dependent regulation of KCNQ5

Juncen Guo
Bin Zhu
Tian Tang
ResearchOpen Access26 Feb 2026
Molecular Psychiatry

P: 1-15
Solvated-intermediate-driven surface transformation of lead halide perovskites

Defective perovskite surfaces limit solar cell efficiency. Liu et al. introduce a small amount of a polar aprotic solvent into the defect passivation solution, enabling surface reconstruction of the perovskite layer and enhancing its overall quality.

Sanwan Liu
Tianyin Miao
Nam-Gyu Park
Research21 Nov 2025
Nature Energy

Volume: 11, P: 109-120
The traditional Chinese medicine Qiliqiangxin in heart failure with reduced ejection fraction: a randomized, double-blind, placebo-controlled trial

In a randomized controlled trial involving patients with heart failure with reduced ejection fraction, treatment with Qiliqiangxin, a traditional Chinese medicine derived from 11 types of plants, decreased the incidence of cardiac events, as compared to placebo.

Iokfai Cheang
Wenming Yao
Xinli Li
ResearchOpen Access02 Aug 2024
Nature Medicine

Volume: 30, P: 2295-2302
Discovery of broad-spectrum fungicides that block septin-dependent infection processes of pathogenic fungi

Very-long-chain fatty acids (VLCFAs) mediate recruitment of septins to the plasma membrane in fungal appressoria, leading to formation of a septin ring at the point of plant infection. VLCFA biosynthesis-inhibiting chemicals prevent septin assembly and have broad-spectrum fungicidal activity.

Min He
Jia Su
Xuewei Chen
Research21 Sept 2020
Nature Microbiology

Volume: 5, P: 1565-1575
Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing

Tumor–normal paired DNA samples from a breast cancer cell line and a matched lymphoblastoid cell line enable calibration of clinical sequencing pipelines and benchmarking ‘tumor-only’ or ‘matched tumor–normal’ analyses.

Li Tai Fang
Bin Zhu
Yuanting Zheng
Research09 Sept 2021
Nature Biotechnology

Volume: 39, P: 1151-1160
Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials

Multi-omics data are readily integrated using quartet reference materials.

Yuanting Zheng
Yaqing Liu
Leming Shi
ResearchOpen Access07 Sept 2023
Nature Biotechnology

Volume: 42, P: 1133-1149
A cocoon silk chemistry strategy to ultrathin N-doped carbon nanosheet with metal single-site catalysts

Single-site catalysts supported by ultrathin two-dimensional (2D) porous matrix are desirable for catalytic reactions, yet their synthesis remains a great challenge. Herein the authors report a cocoon silk chemistry strategy to synthesize isolated metal single-site catalysts embedded in ultrathin 2D porous N-doped carbon nanosheets.

Youqi Zhu
Wenming Sun
Yadong Li
ResearchOpen Access21 Sept 2018
Nature Communications

Volume: 9, P: 1-9
Superselective embolic particle guidance in vessel networks via shape-adaptive acoustic manipulation

Interventional embolization is essential for cancer treatment, but it lacks submillimeter vessel selectivity. Here, the authors show an embolic particle steering in micro-vessel networks via shape-adaptive acoustic manipulation and achieve superselective embolization.

Yucheng Luo
Qiu Yin
Zhichao Ma
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-12
Author Correction: Construction of Pd-Zn dual sites to enhance the performance for ethanol electro-oxidation reaction

Yajun Qiu
Jian Zhang
Yadong Li
Amendments and CorrectionsOpen Access11 Feb 2022
Nature Communications

Volume: 13, P: 1
Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing

Recommendations are given on optimal read coverage and selection of calling algorithm to maximize the reproducibility of cancer mutation detection in whole-genome or whole-exome sequencing.

Wenming Xiao
Luyao Ren
Leming Shi
Research09 Sept 2021
Nature Biotechnology

Volume: 39, P: 1141-1150
IL-21 promotes the anti-tumor effect of anti-CD47 chimeric antigen receptor macrophages in ovarian cancer

The anti-tumor effects of a co-expression strategy of chimeric antigen receptor macrophages with IL-21 was validated in both in vitro and in vivo models of ovarian cancer.

Yizhao Chen
Xiangling Zhu
Jiajie Tu
ResearchOpen Access23 Dec 2025
Communications Biology

Volume: 9, P: 1-11
Quartet RNA reference materials improve the quality of transcriptomic data through ratio-based profiling

A new RNA reference set improves detection of differential expression in clinical settings.

Ying Yu
Wanwan Hou
Yuanting Zheng
ResearchOpen Access07 Sept 2023
Nature Biotechnology

Volume: 42, P: 1118-1132
Structural basis of nonribosomal peptide macrocyclization in fungi

Unlike their bacterial counterparts, fungal nonribosomal peptide synthetases utilize a terminal condensation-like (C_T) domain to form macrocycles, details of which are illuminated by structures of a C_T domain and neighboring thiolation domain.

Jinru Zhang
Nicholas Liu
Jiahai Zhou
Research17 Oct 2016
Nature Chemical Biology

Volume: 12, P: 1001-1003
Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection

In this study, the authors isolated and characterized neutralizing antibodies from vaccinated individuals with SARS-CoV-2 BA.1 breakthrough infection and show that elite antibodies derived from specific germlines provide potent pan-variant neutralization capacity and in vivo protection.

Yu Guo
Guangshun Zhang
Zihe Rao
ResearchOpen Access15 Jun 2023
Nature Communications

Volume: 14, P: 1-16
Chalcogen-bridged coordination polymer for the photocatalytic activation of aryl halides

Chalcogen-bridged naphthalene diimide coordination polymers are designed and synthesised as potent excited state reductants for the activation of inert bonds in a series of aryl halides.

Le Zeng
Tiexin Zhang
Chunying Duan
ResearchOpen Access06 Jul 2023
Nature Communications

Volume: 14, P: 1-13
Author Correction: Quartet RNA reference materials improve the quality of transcriptomic data through ratio-based profiling

Ying Yu
Wanwan Hou
Yuanting Zheng
Amendments and CorrectionsOpen Access02 Oct 2023
Nature Biotechnology

Volume: 42, P: 1150
Construction of Pd-Zn dual sites to enhance the performance for ethanol electro-oxidation reaction

Rational design and synthesis of superior electrocatalysts for ethanol oxidation is crucial to practical applications of direct ethanol fuel cells. Here, authors report the construction of Pd-Zn dual sites with well exposure and uniformity can improve the efficiency of ethanol electro-oxidation.

Yajun Qiu
Jian Zhang
Yadong Li
ResearchOpen Access06 Sept 2021
Nature Communications

Volume: 12, P: 1-9
Geographical influences on thyroid abnormalities in adult population from iodine-replete regions: a cross-sectional study

Xiaofeng Wang
Zhe Mo
Xiaoming Lou
ResearchOpen Access13 Jan 2021
Scientific Reports

Volume: 11, P: 1-7
Decreased bilateral thalamic gray matter volume in first-episode schizophrenia with prominent hallucinatory symptoms: A volumetric MRI study

Peng Huang
Yibin Xi
Hong Yin
ResearchOpen Access25 Sept 2015
Scientific Reports

Volume: 5, P: 1-10
Phosphorylation of LAMP2A by p38 MAPK couples ER stress to chaperone-mediated autophagy

The endoplasmic reticulum (ER) and lysosome are central to cellular stress responses, but it is unclear how ER stress is signaled to lysosomes. Here the authors show that ER stress activates chaperone-mediated autophagy (CMA) via direct phosphorylation of the CMA receptor LAMP2A by the lysosomal p38 MAPK.

Wenming Li
Jinqiu Zhu
Zixu Mao
ResearchOpen Access24 Nov 2017
Nature Communications

Volume: 8, P: 1-14
Metagenomic NGS reveals determinants of polymicrobial spinal infection pathogenesis

Cheng Li
Jichong Zhu
Yang Lin
ResearchOpen Access22 Apr 2025
Scientific Reports

Volume: 15, P: 1-6
Intranasal adenovirus-vectored Omicron vaccine induced nasal immunoglobulin A has superior neutralizing potency than serum antibodies

Si Chen
Zhengyuan Zhang
Ling Chen
ResearchOpen Access22 Jul 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-12
Graph Geometric Algebra networks for graph representation learning

Jianqi Zhong
Wenming Cao
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-13
Evidence for three-dimensional spin–velocity alignment in a pulsar

Fast-moving pulsars and neutron stars in general may have received a kinetic ‘kick’ from an asymmetric element in the supernova explosion that formed them. Here, the spin axis of a pulsar is determined to lie along the three-dimensional direction of the pulsar’s motion, providing a challenging constraint on supernova explosion modelling.

Jumei Yao
Weiwei Zhu
Jiguang Lu
Research06 May 2021
Nature Astronomy

Volume: 5, P: 788-795
Precise gene replacement in rice by RNA transcript-templated homologous recombination

Homology-directed DNA repair using RNA as a template enables precise gene replacement in rice.

Shaoya Li
Jingying Li
Lanqin Xia
Research18 Mar 2019
Nature Biotechnology

Volume: 37, P: 445-450
AZGP1 activation by lenvatinib suppresses intrahepatic cholangiocarcinoma epithelial-mesenchymal transition through the TGF-β1/Smad3 pathway

Liming Deng
Wenming Bao
Gang Chen
ResearchOpen Access05 Sept 2023
Cell Death & Disease

Volume: 14, P: 1-13
Iodine Deficiency in Zhejiang Pregnant Women in the Context of Universal Salt Iodization Programme

Zhifang Wang
Mingluan Xing
Xiaofeng Wang
ResearchOpen Access11 Jun 2018
Scientific Reports

Volume: 8, P: 1-7
IGFBP5 affects cardiomyocyte survival and functional recovery in mice following myocardial ischemia

IGFBP5 regulates cardiomyocyte proliferation and apoptosis during cardiac repair in mice by activating the IGF1R/AKT signalling pathway, representing a potential therapeutic target for myocardial ischemic injury.

Qingqing Zhu
Xinyi Lu
Shengen Liao
ResearchOpen Access29 Nov 2024
Communications Biology

Volume: 7, P: 1-13
Autologous glueless simple oral mucosal transplantation for the repair of limbal stem cell deficiency ocular surface in a rabbit model

Kai Zhang
Wei Liu
Lin Shen
ResearchOpen Access29 Mar 2025
Scientific Reports

Volume: 15, P: 1-10
Rice transcription factor bHLH25 confers resistance to multiple diseases by sensing H₂O₂

Haicheng Liao
Yu Fang
Xuewei Chen
ResearchOpen Access14 Jan 2025
Cell Research

Volume: 35, P: 205-219
Physical activity modifies the association between CYBA gene polymorphisms and small artery elasticity in a Chinese population

Zhenyan Zhu
Haifeng Zhang
Xinli Li
Research23 Feb 2012
Hypertension Research

Volume: 35, P: 739-744
Hepatic SMARCA4 predicts HCC recurrence and promotes tumour cell proliferation by regulating SMAD6 expression

Zhiao Chen
Xinyuan Lu
Xianghuo He
ResearchOpen Access19 Jan 2018
Cell Death & Disease

Volume: 9, P: 1-12
Genetic mapping with testcrossing associations and F_2:3 populations reveals the importance of heterosis in chilling tolerance at maize seedling stage

Jinbo Yan
Yu Wu
Bing Yue
ResearchOpen Access12 Jun 2017
Scientific Reports

Volume: 7, P: 1-9
Nonlinear associations of serum cobalamin with risk of all-cause and cardiovascular mortality in hypertensive adults

This study was a prospective cohort study that included serum cobalamin data from 9934 hypertensive adults from the NHANES from 1999–2006 and 20011–2014. Findings suggested that both lower and higher serum cobalamin concentrations were associated with a higher risk of cardiovascular and all-cause mortality in hypertensive adults.

Xu Zhu
Yuan Tang
Xinli Li
Research20 Feb 2023
Hypertension Research

Volume: 46, P: 1276-1286
Comparison of arterial stiffness indices measured by pulse wave velocity and pulse wave analysis for predicting cardiovascular and all-cause mortality in a Chinese population

Xin Yue
Lu Chen
Haifeng Zhang
Research09 Jan 2024
Hypertension Research

Volume: 47, P: 767-777
Resting-state brain functional alterations and their genetic mechanisms in drug-naive first-episode psychosis

Qian Li
Xiaotao Xu
Yongqiang Yu
ResearchOpen Access25 Feb 2023
Schizophrenia

Volume: 9, P: 1-13
Bilayer and three dimensional conductive network composed by SnCl₂ reduced rGO with CNTs and GO applied in transparent conductive films

Ying Tian
Ning Guo
Hong-Zhang Geng
ResearchOpen Access10 May 2021
Scientific Reports

Volume: 11, P: 1-12
A single-agent fusion of human IL-2 and anti-IL-2 antibody that selectively expands regulatory T cells

A single-agent fusion of human IL-2 and antiIL-2 antibody is discovered and engineered to selectively expand regulatory T cells and to treat autoimmune diseases.

Yuan Lin
Xue Wang
Cheng Liao
ResearchOpen Access09 Mar 2024
Communications Biology

Volume: 7, P: 1-14
Nomogram model for decompressing craniectomy after mechanical thrombectomy in patients with acute ischemic stroke

Yingcong Wei
Jing Xiao
Gang Zhu
ResearchOpen Access21 Jan 2025
Scientific Reports

Volume: 15, P: 1-13
Comprehensive overview of microRNA function in rheumatoid arthritis

Xiaole Peng
Qing Wang
Dechun Geng
ReviewsOpen Access24 Jan 2023
Bone Research

Volume: 11, P: 1-24
Whole genome and exome sequencing reference datasets from a multi-center and cross-platform benchmark study

Yongmei Zhao
Li Tai Fang
Wenming Xiao
ResearchOpen Access09 Nov 2021
Scientific Data

Volume: 8, P: 1-14
Autologous hematopoietic stem cell transplantation activity for lymphoma and multiple myeloma in China

Weiping Liu
Jie Ji
Jun Zhu
Correspondence17 Dec 2022
Bone Marrow Transplantation

Volume: 58, P: 349-352

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