Nature Search

Interactive symbolic regression with co-design mechanism through offline reinforcement learning

Symbolic Regression is a method for uncovering mathematical and physical relationships from data. Here, the authors propose Sym-Q, an interactive reinforcement learning-based framework with a co-design mechanism that enables efficient and guided equation discovery.

Yuan Tian
Wenqi Zhou
Olga Fink
ResearchOpen Access26 Apr 2025
Nature Communications

Volume: 16, P: 1-12
A membrane associated tandem kinase from wild emmer wheat confers broad-spectrum resistance to powdery mildew

Powdery mildew is a fungal leaf disease that reduces yield and grain quality in susceptible wheat varieties. Here, the authors report the cloning of the wild emmer wheat originated powdery mildew resistance gene Pm36 as a membrane associated tandem kinase and its possible resistance mechanism.

Miaomiao Li
Huaizhi Zhang
Zhiyong Liu
ResearchOpen Access10 Apr 2024
Nature Communications

Volume: 15, P: 1-14
The SUN-family protein Sad1 mediates heterochromatin spatial organization through interaction with histone H2A-H2B

Here authors identify the interaction between the SUN-family protein Sad1 and histone H2A-H2B in S. pombe, and reveal the roles of the Sad1-histone interaction in the association of heterochromatin with the nuclear envelope and heterochromatin silencing.

Wenqi Sun
Qianhua Dong
Yong Chen
ResearchOpen Access21 May 2024
Nature Communications

Volume: 15, P: 1-13
Basement membrane perforations guide anterior–posterior axis formation

Chen et al. show that in mice, extracellular matrix remodeling drives early migration of the anterior signaling center, establishing the body axis sooner than expected—a mechanism potentially conserved in humans.

Dong-Yuan Chen
Nikolas H. Claussen
Magdalena Zernicka-Goetz
ResearchOpen Access22 Jul 2025
Nature Communications

Volume: 16, P: 1-19
Differential selection of yield and quality traits has shaped genomic signatures of cowpea domestication and improvement

High-quality genome assemblies of grain and vegetable cowpeas and re-sequencing of 344 accessions characterize genomic variations between cowpea subspecies and their domestication and improvement under selection.

Xinyi Wu
Zhongyuan Hu
Guojing Li
Research22 Apr 2024
Nature Genetics

Volume: 56, P: 992-1005
Study on the mechanisms associating community outdoor public spaces with elderly behavior

Lei Wang
Wenqi He
Hu Yin
ResearchOpen Access22 Aug 2025
Scientific Reports

Volume: 15, P: 1-32
Creating three-dimensional magnetic functional microdevices via molding-integrated direct laser writing

Magnetic, wireless miniature devices are promising for healthcare, information technology, and many other field but lack advanced fabrication methods for micrometer length scales. Here authors present a molding-integrated direct laser writing fabrication protocol to fabricate 3D micron-scale devices with programmable magnetization and multi-material integration.

Zemin Liu
Meng Li
Metin Sitti
ResearchOpen Access19 Apr 2022
Nature Communications

Volume: 13, P: 1-11
Multi-functional soft-bodied jellyfish-like swimming

It is challenging to reduce the size of untethered swimming robots whilst keeping their multiple manipulation and other functions. Ren et al. achieve this goal using a jellyfish-inspired soft millirobot design in an oscillating magnetic field, which can be operated in fluids with moderate Reynolds numbers.

Ziyu Ren
Wenqi Hu
Metin Sitti
ResearchOpen Access02 Jul 2019
Nature Communications

Volume: 10, P: 1-12
Naturally occurring dinactin targets cpsA protein and kills Mycobacterium tuberculosis by disrupting the proton motive force

Dinactin disrupts the proton motive force of the cell membrane of Mycobacterium tuberculosis by targeting the LCP family protein and thereby kills the Mycobacterium tuberculosis in vitro and in vivo.

Gaoyan Wang
Wenqi Dong
Chen Tan
ResearchOpen Access12 Feb 2026
Communications Biology

Volume: 9, P: 1-17
Adaptive wireless millirobotic locomotion into distal vasculature

Accessibility into the distal vascular systems to treat various diseases remains challenging using medical catheters. Here, Wang et al. demonstrate that a stent-shaped wireless magnetic soft robot enables adaptive locomotion and medical functions into these distal vascular regions.

Tianlu Wang
Halim Ugurlu
Metin Sitti
ResearchOpen Access01 Aug 2022
Nature Communications

Volume: 13, P: 1-17
Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation

Cancer cells exploit immune checkpoint pathways, such as PD-1/PD-L1, to evade elimination by the immune system. Here, the authors demonstrate that TMUB1 regulates post-translational modifications of PD-L1 and that targeting the TMUB1/PD-L1 interaction promotes anti-tumour T cells responses

Chengyu Shi
Ying Wang
Aifu Lin
ResearchOpen Access14 Nov 2022
Nature Communications

Volume: 13, P: 1-18
Correction: The harmful effects of acute PM2.5 exposure to the heart and a novel preventive and therapeutic function of CEOs

Lu Dong
Wenping Sun
Laiyu Song
Amendments and CorrectionsOpen Access16 Dec 2025
Scientific Reports

Volume: 15, P: 1-3
Variability in water quality and chlorophyll a in the middle route of the south to north water diversion project

Aiping Huang
Xiaobo Liu
Xiaochen Yang
ResearchOpen Access05 Nov 2025
Scientific Reports

Volume: 15, P: 1-13
Unravelling the combination of medical and elderly care in China: a comprehensive policy analysis

Ziyi Wang
Pu Han
Wenqi Chen
ResearchOpen Access11 Sept 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-17
Integrating single-cell and spatial transcriptomics reveals the cellular heterogeneity of vestibular schwannoma

Wenqi Dong
Yuchen Jin
Dongzhen Yu
ResearchOpen Access08 Jul 2025
npj Precision Oncology

Volume: 9, P: 1-15
A rare gain of function mutation in a wheat tandem kinase confers resistance to powdery mildew

Powdery mildew is a major threat to world wheat yields. Here the authors describe the map-based cloning of Pm24, a gain-of-function powdery mildew resistance allele that encodes a tandem kinase-pseudokinase protein with a deletion in a kinase domain that is endemic to certain wheat landraces.

Ping Lu
Li Guo
Zhiyong Liu
ResearchOpen Access03 Feb 2020
Nature Communications

Volume: 11, P: 1-11
Author Correction: Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation

Chengyu Shi
Ying Wang
Aifu Lin
Amendments and CorrectionsOpen Access10 Dec 2024
Nature Communications

Volume: 15, P: 1-4
Bioinspired rotary flight of light-driven composite films

Light-driven actuators have great potential in different types of applications but is still challenging to apply them in flying devices owing to their slow response, small deflection and force output. Here, the authors report a rotary flying photoactuator with fast rotation and rapid response.

Dan Wang
Zhaomin Chen
Metin Sitti
ResearchOpen Access21 Aug 2023
Nature Communications

Volume: 14, P: 1-11
Organic phosphorescent scintillation from copolymers by X-ray irradiation

The authors achieved the X-ray-excited organic phosphorescent scintillation from copolymers through copolymerization of bromine-substituted chromophores and acrylic acid and demonstrated their potential application in X-ray radiography.

Nan Gan
Xin Zou
Wei Huang
ResearchOpen Access09 Jul 2022
Nature Communications

Volume: 13, P: 1-8
Lower pork consumption and technological change in feed production can reduce the pork supply chain environmental footprint in China

Integrated structural and technological changes across the Chinese pork supply chain can improve production and meet demand while reducing phosphorous and nitrogen losses.

Bingxin Tong
Ling Zhang
Fusuo Zhang
Research22 Dec 2022
Nature Food

Volume: 4, P: 74-83
Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly

Primary microcephaly is a clinical feature of several human telomere disorder syndromes. Here the authors reveal a role of Microcephalin 1 in promoting telomere replication and repair.

Alessandro Cicconi
Rekha Rai
Sandy Chang
ResearchOpen Access17 Nov 2020
Nature Communications

Volume: 11, P: 1-18
LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress

Liu et al. show that, in response to energy stress, the NBR2 long non-coding RNA binds AMPK and promotes its activity to reduce cancer cell proliferation. Conversely, loss of NBR2 inhibits AMPK, leading to mTOR activation and tumour growth.

Xiaowen Liu
Zhen-Dong Xiao
Boyi Gan
Research21 Mar 2016
Nature Cell Biology

Volume: 18, P: 431-442
Nonlinear time domain and multi-scale frequency domain feature fusion for time series forecasting

Kejiang Xiao
Yefeng Li
Liang Chen
ResearchOpen Access16 Aug 2025
Scientific Reports

Volume: 15, P: 1-13
AMPK modulates Hippo pathway activity to regulate energy homeostasis

In two related papers, Chen and colleagues and Guan and colleagues report a crucial role for the AMPK and Hippo pathways in glucose homeostasis. Starvation triggers AMPK-mediated phosphorylation and inactivation of YAP.

Wenqi Wang
Zhen-Dong Xiao
Junjie Chen
Research09 Mar 2015
Nature Cell Biology

Volume: 17, P: 490-499
Dianxianning improved amyloid β-induced pathological characteristics partially through DAF-2/DAF-16 insulin like pathway in transgenic C. elegans

Dejuan Zhi
Dong Wang
Hongyu Li
ResearchOpen Access12 Sept 2017
Scientific Reports

Volume: 7, P: 1-13
Dynamics of oxygen evolution in a thermally stratified reservoir under climate warming

Bing Ma
Fei Dong
Aiping Huang
ResearchOpen Access18 Nov 2025
Scientific Reports

Volume: 15, P: 1-18
Improving explainable AI with patch perturbation-based evaluation pipeline: a COVID-19 X-ray image analysis case study

Jimin Sun
Wenqi Shi
May D. Wang
ResearchOpen Access09 Nov 2023
Scientific Reports

Volume: 13, P: 1-18
The harmful effects of acute PM_2.5 exposure to the heart and a novel preventive and therapeutic function of CEOs

Lu Dong
Wenping Sun
Laiyu Song
ResearchOpen Access05 Mar 2019
Scientific Reports

Volume: 9, P: 1-12
Chromosome-level genome sequencing and assembly of the parasitoid wasp Leptopilina myrica

Zhi Dong
Zixuan Xu
Jiani Chen
ResearchOpen Access08 Feb 2025
Scientific Data

Volume: 12, P: 1-7
The epigenetic regulators EP300/CREBBP represent promising therapeutic targets in MLL-rearranged acute myeloid leukemia

Wenqi Wu
Yanan Jiang
Zhigang Zhao
ResearchOpen Access01 May 2024
Cell Death Discovery

Volume: 10, P: 1-9
Author Correction: H3K14me3 genomic distributions and its regulation by KDM4 family demethylases

Bin Zhao
Wenqi Xu
Fei Lan
Amendments and Corrections17 Dec 2018
Cell Research

Volume: 29, P: 90
FKBP51 promotes invasion and migration by increasing the autophagic degradation of TIMP3 in clear cell renal cell carcinoma

Shaowei Mao
Di Zhang
Muyun Wei
ResearchOpen Access01 Oct 2021
Cell Death & Disease

Volume: 12, P: 1-15
SPINK13 acts as a tumor suppressor in hepatocellular carcinoma by inhibiting Akt phosphorylation

Yongzhi Lun
Jie Sun
Wenqi Zhao
ResearchOpen Access13 Nov 2024
Cell Death & Disease

Volume: 15, P: 1-17
Development of machine learning-based predictors for early diagnosis of hepatocellular carcinoma

Zi-Mei Zhang
Yuting Huang
Hongli Du
ResearchOpen Access04 Mar 2024
Scientific Reports

Volume: 14, P: 1-11
Integrated analysis of the transcriptome, sRNAome, and degradome reveals the network regulating fruit skin coloration in sponge gourd (Luffa cylindrica)

Yuyan Sun
Huiqing Zhang
Qizan Hu
ResearchOpen Access28 Feb 2022
Scientific Reports

Volume: 12, P: 1-21
Cryo-EM structures of human organic anion transporting polypeptide OATP1B1

Ziyang Shan
Xuemei Yang
Yanqing Zhang
ResearchOpen Access06 Sept 2023
Cell Research

Volume: 33, P: 940-951
The Effect of rhCygb on CCl₄-Induced Hepatic Fibrogenesis in Rat

Zhen Li
Wei Wei
Wenqi Dong
ResearchOpen Access23 Mar 2016
Scientific Reports

Volume: 6, P: 1-11
Protective effects of recombinant human cytoglobin against chronic alcohol-induced liver disease in vivo and in vitro

Jian Wen
Yongbin Wu
Wenqi Dong
ResearchOpen Access27 Jan 2017
Scientific Reports

Volume: 7, P: 1-9
H3K14me3 genomic distributions and its regulation by KDM4 family demethylases

Bin Zhao
Wenqi Xu
Fei Lan
Correspondence18 Oct 2018
Cell Research

Volume: 28, P: 1118-1120
Telomere-to-telomere genome assembly of the goose Anser cygnoides

Hongchang Zhao
Hao Zhou
Jian Wang
ResearchOpen Access07 Jul 2024
Scientific Data

Volume: 11, P: 1-9

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