The authors use optical activation and cell type–specific pharmacogenetic silencing in vitro to show that dendritic inhibition critically regulates input-output transformations in mouse hippocampal CA1 pyramidal cells. Dendrite-targeting interneurons are themselves modulated by interneurons targeting pyramidal cell somata.
- Matthew Lovett-Barron
- Gergely F Turi
- Attila Losonczy
