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Scientific Reports (17)
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Showing 1–50 of 58 results

Advanced filters: Author: Xingguang Liu Clear advanced filters

Restoration of RBM22 overcomes the transcriptional and epigenetic barriers of cardiomyocyte proliferation for heart regeneration

Activating endogenous cardiomyocyte proliferation holds great therapeutic promise for cardiac repair. Here, the authors find that RBM22 overcomes the epigenetic obstacles of cardiomyocyte proliferation by recruiting SMARCA4 to promote chromatin accessibility at cell cycle gene promoters, establishing it as a potential therapeutic target for cardiac regeneration.

Xuewen Duan
Yong Tan
Zhenzhen Zhan
ResearchOpen Access09 Mar 2026
Nature Communications

P: 1-22
Organocatalyzed diastereo- and enantioselective synthesis of N–N atropisomeric isoindolinones bearing central chirality

Methods for catalytically constructing of N–N axially chiral scaffolds have garnered significant attention. Here, the authors report a highly diastereoselective and enantioselective organocatalyzed [4 + 1] annulation method for synthesizing diverse valuable isoindolinones that possessing N–N axial and central chiralities.

Xingguang Li
Xin-Ze Wang
Pei-Nian Liu
ResearchOpen Access15 Feb 2025
Nature Communications

Volume: 16, P: 1-11
Publisher Correction: Role of the BUB3 protein in phragmoplast microtubule reorganization during cytokinesis

Hongchang Zhang
Xingguang Deng
Bo Liu
Amendments and Corrections07 Aug 2018
Nature Plants

Volume: 4, P: 731
Erratum: Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity.

Xia Li
Qian Zhang
Xuetao Cao
Amendments and Corrections19 Jul 2016
Nature Immunology

Volume: 17, P: 1005
A meta-analysis of interaction between Epstein-Barr virus and HLA-DRB1*1501 on risk of multiple sclerosis

Di Xiao
Xingguang Ye
Chunxia Jing
ResearchOpen Access11 Dec 2015
Scientific Reports

Volume: 5, P: 1-7
Arabidopsis α-Aurora kinase plays a role in cytokinesis through regulating MAP65-3 association with microtubules at phragmoplast midzone

Arabidopsis α-Aurora kinase regulates plant cytokinesis by phosphorylating the microtubule-associated protein MAP65-3, which controls the dynamic organization of the phragmoplast structure essential for cytokinesis completion.

Xingguang Deng
Yu Xiao
Honghui Lin
ResearchOpen Access06 May 2024
Nature Communications

Volume: 15, P: 1-14
Anti-swelling and self-activating artificial proteoglycan assemblies as cartilaginous implant for post-microfracture healing

The insufficient structure and biofunction of cartilaginous implant impede cartilage regeneration. Here, the authors develop anti-swelling and self-activating artificial proteoglycan assemblies for post-microfracture healing by downregulate calcium signaling pathway and reducing ossification.

Zhulian Li
Mingda Zhao
Yong Sun
ResearchOpen Access06 Dec 2025
Nature Communications

Volume: 17, P: 1-14
Selective oxidative protection leads to tissue topological changes orchestrated by macrophage during ulcerative colitis

Ulcerative colitis is associated with increased infiltration and cellularity, yet the precise tissue topology remains poorly understood. Here the authors employ imaging mass cytometry and single-cell RNA sequencing to characterise intestinal lesions in patients with ulcerative colitis, and show the architecture at the individual cell level which includes a decrease in the resident macrophage population.

Juan Du
Junlei Zhang
Jianpeng Sheng
ResearchOpen Access21 Jun 2023
Nature Communications

Volume: 14, P: 1-17
Role of the BUB3 protein in phragmoplast microtubule reorganization during cytokinesis

During the cell cycle, BUB3 acts in spindle assembly checkpoint control. In plants, it is also involved in phragmoplast formation, interacting with microtubule-associated proteins to coordinate the expansion of the phragmoplast microtubule array.

Hongchang Zhang
Xingguang Deng
Bo Liu
Research02 Jul 2018
Nature Plants

Volume: 4, P: 485-494
Constitutive MHC class I molecules negatively regulate TLR-triggered inflammatory responses via the Fps–SHP-2 pathway

Major histocompatibility complex (MHC) molecules are known to mediate reverse signaling. Cao and colleagues show that reverse signaling via MHC class I attenuates Toll-like receptor–triggered innate inflammatory responses through an Fps–SHP-2 pathway.

Sheng Xu
Xingguang Liu
Xuetao Cao
Research22 Apr 2012
Nature Immunology

Volume: 13, P: 551-559
A kinetochore-associated kinesin-7 motor cooperates with BUB3.3 to regulate mitotic chromosome congression in Arabidopsis thaliana

This study identifies a kinesin motor at kinetochores that teams up with a key mitotic checkpoint protein to orchestrate proper chromosome movement during plant cell division, revealing a plant-specific mechanism for maintaining genetic integrity.

Xiaoya Tang
Ying He
Xingguang Deng
Research16 Oct 2024
Nature Plants

Volume: 10, P: 1724-1736
Loss of KDM5B ameliorates pathological cardiac fibrosis and dysfunction by epigenetically enhancing ATF3 expression

Bo Wang
Yong Tan
Zhenzhen Zhan
ResearchOpen Access08 Dec 2022
Experimental & Molecular Medicine

Volume: 54, P: 2175-2187
Urban expansion identification and change analysis in Panjin China from 1990 to 2020

Zhai Jiang
Jing Li
Zhen Yang
ResearchOpen Access03 Dec 2025
Scientific Reports

Volume: 16, P: 1-17
Characterization of Copoly(p-hydroxybenzoate/bisphenol A terephthalate) by NMR Spectroscopy

Yong Wang
Dacheng Wu
Ruixia Li
Research01 Oct 1996
Polymer Journal

Volume: 28, P: 896-900
Legume rhizodeposition promotes nitrogen fixation by soil microbiota under crop diversification

Sustainability in agriculture can be improved harnessing biological N₂ fixation in legumes. Here, the authors combine different crops with peanut plants finding that maize and oilseed rape are the most successful combinations which have potential to enhance rhizosphere microbiota N₂ fixation.

Mengjie Qiao
Ruibo Sun
Yan Chen
ResearchOpen Access04 Apr 2024
Nature Communications

Volume: 15, P: 1-15
Perception of motion salience shapes the emergence of collective motions

Understanding the decentralized self-organization in animal groups helps design swarm robotics, yet the underlying mechanism remains elusive. Xiao et al. analyze collective motions of three large bird-flocking datasets and translate their findings to guide evacuation of a swarm of miniature robots in confinement.

Yandong Xiao
Xiaokang Lei
Xingguang Peng
ResearchOpen Access05 Jun 2024
Nature Communications

Volume: 15, P: 1-16
Continuous epitaxy of single-crystal graphite films by isothermal carbon diffusion through nickel

Isothermal dissolution–diffusion–precipitation of carbon drives continuous epitaxial growth of single-crystal multilayer graphene.

Zhibin Zhang
Mingchao Ding
Kaihui Liu
Research27 Oct 2022
Nature Nanotechnology

Volume: 17, P: 1258-1264
Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity

The DNA methyltransferase Dnmt3a has not been studied in innate immunity. Cao and colleagues show that Dnmt3a enhances antiviral responses via a non-canonical mechanism to activate the kinase TBK1 and the production of type I interferons in macrophages.

Xia Li
Qian Zhang
Xuetao Cao
Research30 May 2016
Nature Immunology

Volume: 17, P: 806-815
Correction: Targeting KAT8 alleviates self-RNA-driven skin inflammation by modulating histone H4 lysine 16 acetylation in psoriasis

Yan Xiang
Yuyu Jiang
Xingguang Liu
Amendments and Corrections14 Jan 2026
Cell Death & Differentiation

P: 1
The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ

MicroRNAs contribute to post-transcriptional controls that fine-tune protein expression. Cao and colleagues identify the microRNA miR-29 as a regulator of the expression of interferon-γ protein and show that intracellular infection with pathogens dampens miR-29 expression.

Feng Ma
Sheng Xu
Xuetao Cao
Research24 Jul 2011
Nature Immunology

Volume: 12, P: 861-869
Tracing the transmission dynamics of HIV-1 CRF55_01B

Junjie Zai
Haizhou Liu
Xingguang Li
ResearchOpen Access20 Mar 2020
Scientific Reports

Volume: 10, P: 1-8
Methyltransferase Dot1l preferentially promotes innate IL-6 and IFN-β production by mediating H3K79me2/3 methylation in macrophages

Xiang Chen
Xingguang Liu
Xuetao Cao
Research01 Oct 2018
Cellular & Molecular Immunology

Volume: 17, P: 76-84
Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk

MHC class II is typically involved in the presentation of peptide antigen to CD4⁺ T cells. Cao and colleagues identify a previously unknown intracellular function for MHC class II in promoting Toll-like receptor signaling.

Xingguang Liu
Zhenzhen Zhan
Xuetao Cao
Research27 Mar 2011
Nature Immunology

Volume: 12, P: 416-424
The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a β-catenin-dependent pathway

Intracellular nucleic acid sensors trigger the production of type I interferon. Cao and colleagues identify LRRFIP1 as a cytosolic nucleic acid–binding protein that mediates the production of type I interferon via a β-catenin-dependent pathway.

Pengyuan Yang
Huazhang An
Xuetao Cao
Research09 May 2010
Nature Immunology

Volume: 11, P: 487-494
Spatial change, time tendency and projection to HIV/AIDS incidence in an eastern province of China

Yiwei Li
Shijia Yuan
Chunlei Han
ResearchOpen Access19 May 2025
Scientific Reports

Volume: 15, P: 1-11
Quinone methides and indole imine methides as intermediates in enantioselective catalysis

Catalytic asymmetric transformations of quinone methides and indole imine methides involve catalysts such as chiral Brønsted acids, Lewis acids and bases as well as transition metal complexes. In this Review, these asymmetric transformations are discussed with a focus on reaction pathways and activation modes.

Xingguang Li
Zhiyang Li
Jianwei Sun
Reviews06 Jun 2022
Nature Synthesis

Volume: 1, P: 426-438
Flexible and sensitive pressure sensor with enhanced breathability for advanced wearable health monitoring

Xingguang Chen
Chenhao Wang
Hui Kong
ResearchOpen Access26 Sept 2025
npj Flexible Electronics

Volume: 9, P: 1-12
Tracing the epidemic history of HIV-1 CRF01_AE clusters using near-complete genome sequences

Xingguang Li
Haizhou Liu
Yiming Shao
ResearchOpen Access22 Jun 2017
Scientific Reports

Volume: 7, P: 1-11
Association between hematocrit-to-albumin ratio and acute kidney injury in patients with acute pancreatitis: a retrospective cohort study

Wen Wu
Yupei Zhang
Zhaohui Zhang
ResearchOpen Access07 Nov 2024
Scientific Reports

Volume: 14, P: 1-11
Targeting KAT8 alleviates self-RNA-driven skin inflammation by modulating histone H4 lysine 16 acetylation in psoriasis

Yan Xiang
Yuyu Jiang
Xingguang Liu
Research21 Jul 2025
Cell Death & Differentiation

Volume: 33, P: 327-342
Hydrangea paniculata coumarins attenuate experimental membranous nephritis by bidirectional interactions with the gut microbiota

The coumarin extract of peegee hydrangea reverses gut microbiome dysbiosis, therefore exerting a protective effect against experimental membranous nephritis in rats.

Zhaojun Li
Xingguang Zhang
Sen Zhang
ResearchOpen Access22 Nov 2023
Communications Biology

Volume: 6, P: 1-14
Glycolipid iGb3 feedback amplifies innate immune responses via CD1d reverse signaling

Xingguang Liu
Peng Zhang
Xuetao Cao
Research04 Dec 2018
Cell Research

Volume: 29, P: 42-53
A significant, functional and replicable risk KTN1 variant block for schizophrenia

Qiao Mao
Xiandong Lin
Xingguang Luo
ResearchOpen Access08 Mar 2023
Scientific Reports

Volume: 13, P: 1-13
The 2014 Ebola virus outbreak in West Africa highlights no evidence of rapid evolution or adaptation to humans

Xingguang Li
Junjie Zai
Yiming Shao
ResearchOpen Access21 Oct 2016
Scientific Reports

Volume: 6, P: 1-9
Geographic origin and evolutionary history of China’s two predominant HIV-1 circulating recombinant forms, CRF07_BC and CRF08_BC

Yi Feng
Yutaka Takebe
Yiming Shao
ResearchOpen Access14 Jan 2016
Scientific Reports

Volume: 6, P: 1-10
Histone demethylase KDM5B licenses macrophage-mediated inflammatory responses by repressing Nfkbia transcription

Yunkai Zhang
Ying Gao
Xingguang Liu
Research13 Mar 2023
Cell Death & Differentiation

Volume: 30, P: 1279-1292
Murine neonatal cardiac B cells promote cardiomyocyte proliferation and heart regeneration

Yong Tan
Xuewen Duan
Zhenzhen Zhan
ResearchOpen Access11 Feb 2023
npj Regenerative Medicine

Volume: 8, P: 1-7
Retraction Note: MIR600HG sponges miR-125a-5p to regulate glycometabolism and cisplatin resistance of oral squamous cell carcinoma cells via mediating RNF44

Xingguang Liu
Tengda Zhao
Shaohua Ge
Amendments and CorrectionsOpen Access22 Nov 2023
Cell Death Discovery

Volume: 9, P: 1
MicroRNA-21 prevents excessive inflammation and cardiac dysfunction after myocardial infarction through targeting KBTBD7

Linshan Yang
Bo Wang
Zhenzhen Zhan
ResearchOpen Access10 Jul 2018
Cell Death & Disease

Volume: 9, P: 1-14
Epidemiology of cardiovascular disease in China: current features and implications

Cardiovascular disease (CVD) is the leading cause of death in China. In this Review, Zhao and colleagues summarize eight important features of the evolving epidemiology of CVD in China and discuss how this information can help to develop effective and timely strategies to prevent and treat CVD.

Dong Zhao
Jing Liu
Mengge Zhou
Reviews22 Nov 2018
Nature Reviews Cardiology

Volume: 16, P: 203-212
RBM25 is required to restrain inflammation via ACLY RNA splicing-dependent metabolism rewiring

Yunkai Zhang
Ying Gao
Xingguang Liu
Research09 Sept 2024
Cellular & Molecular Immunology

Volume: 21, P: 1231-1250
KDM2B promotes IL-6 production and inflammatory responses through Brg1-mediated chromatin remodeling

Qingqing Zhou
Yunkai Zhang
Zhenzhen Zhan
Research13 Jun 2019
Cellular & Molecular Immunology

Volume: 17, P: 834-842
Author Correction: Bromodomain protein Brd3 promotes Ifnb1 transcription via enhancing IRF3/p300 complex formation and recruitment to Ifnb1 promoter in macrophages

Wenhui Ren
Chunmei Wang
Nan Li
Amendments and CorrectionsOpen Access01 Dec 2020
Scientific Reports

Volume: 10, P: 1
The role of Mean Platelet Volume/platelet count Ratio and Neutrophil to Lymphocyte Ratio on the risk of Febrile Seizure

Zhigang Liu
Xiangxin Li
Xingguang Ye
ResearchOpen Access11 Oct 2018
Scientific Reports

Volume: 8, P: 1-10
The different impacts of pain-related negative emotion and trait negative emotion on brain function in patients with inflammatory bowel disease

Ling Yang
Lingqin Zhang
Jinhua Cai
ResearchOpen Access12 Oct 2024
Scientific Reports

Volume: 14, P: 1-12
Autophagy induced by DAMPs facilitates the inflammation response in lungs undergoing ischemia-reperfusion injury through promoting TRAF6 ubiquitination

Xingguang Liu
Hao Cao
Zhenzhen Zhan
ResearchOpen Access03 Feb 2017
Cell Death & Differentiation

Volume: 24, P: 683-693
RETRACTED ARTICLE: MIR600HG sponges miR-125a-5p to regulate glycometabolism and cisplatin resistance of oral squamous cell carcinoma cells via mediating RNF44

Xingguang Liu
Tengda Zhao
Shaohua Ge
ResearchOpen Access20 Apr 2022
Cell Death Discovery

Volume: 8, P: 1-10
SNP rs10420324 in the AMPA receptor auxiliary subunit TARP γ-8 regulates the susceptibility to antisocial personality disorder

Shi-Xiao Peng
Yue-Ying Wang
Yun Stone Shi
ResearchOpen Access07 Jun 2021
Scientific Reports

Volume: 11, P: 1-15
Exploring the mechanism of “Rare Earth” texture evolution in a lean Mg–Zn–Ca alloy

Dikai Guan
Xingguang Liu
W. Mark Rainforth
ResearchOpen Access09 May 2019
Scientific Reports

Volume: 9, P: 1-11
Interferon-inducible cytoplasmic lncLrrc55-AS promotes antiviral innate responses by strengthening IRF3 phosphorylation

Yumei Zhou
Mengxuan Li
Xuetao Cao
Research18 Jun 2019
Cell Research

Volume: 29, P: 641-654

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