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Showing 1–2 of 2 results
Advanced filters: Author: Yexi Peng Clear advanced filters

  • Application of CT imaging to renal function evaluation is limited due to nonspecific distribution and nephrotoxicity of clinical iodinated contrast agents. Here the authors report the preclinical development of a kidney tubule-targeting and renoprotective CT contrast nanoagent (E-Au-Agent) for detection and repair of kidney injury.

    • Mingze Xu
    • Yuming Qi
    • Bujie Du
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17

  • The development of nanocarriers for targeted protein delivery requires methods for high-throughput screening in vitro and in vivo. Here authors develop a DNA-barcoded method to identify nanocarriers with different biodistributions, and demonstrate delivery of catalase to the kidneys of female mice, successfully mitigating cisplatin-induced acute kidney injury.

    • Luyao Wang
    • Wen Zhou
    • Juanjuan Du
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15