Nature Search

Two dynamically competing factors determine the translation start site

To start, or not to start, that is the recurring question faced by eukaryotic ribosomes as they scan mRNA for translation start sites. A study now shows that two opposing initiation factors, which bind the ribosome in a mutually exclusive manner, assist in this decision-making process.

Yi-Lan Chen
Jin-Der Wen
News & Views02 Sept 2025
Nature Structural & Molecular Biology

Volume: 32, P: 2134-2135
Targeting MORF4L1-mediated DNA repair potentiates RT-induced antitumor immunity via cGAS-STING activation in hepatocellular carcinoma

Si-Wei Wang
Wei-Feng Hong
Shi-Suo Du
Research05 Nov 2025
Cellular & Molecular Immunology

Volume: 22, P: 1549-1566
Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair

The cellular function of active DNA demethylation in neurons is not well understood. Here, Song and colleagues show that synaptic activity modulates Tet3 signaling, which in turn regulates glutamatergic synaptic transmission and synaptic scaling. Their work identifies Tet3 as a synaptic activity sensor to epigenetically regulate fundamental properties and meta-plasticity of neurons via active DNA demethylation.

Huimei Yu
Yijing Su
Hongjun Song
Research27 Apr 2015
Nature Neuroscience

Volume: 18, P: 836-843
Genome-scale long noncoding RNA expression pattern in squamous cell lung cancer

Ying Wang
Chen-Yue Qian
Zhao-Qian Liu
ResearchOpen Access10 Jul 2015
Scientific Reports

Volume: 5, P: 1-11
Data from multi-national aging cohorts show dysregulated metabolic pathways in people with physio-cognitive decline

Huang et al. investigate serum metabolomic profiles from aging cohorts in Taiwan and Japan to identify biomarkers of physio-cognitive decline syndrome. They report significant alterations in glutathione, tryptophan, and bile acid pathways, with metabolites including creatinine and 3-hydroxykynurenine as potential indicators.

Yi-Long Huang
Wei-Ju Chang
Liang-Kung Chen
ResearchOpen Access14 Aug 2025
Communications Medicine

Volume: 5, P: 1-9
Preoperative %p2PSA and Prostate Health Index Predict Pathological Outcomes in Patients with Prostate Cancer Undergoing Radical Prostatectomy

Yung-Ting Cheng
Chao-Yuan Huang
Chih-Hung Chiang
ResearchOpen Access21 Jan 2020
Scientific Reports

Volume: 10, P: 1-7
Using feral pigeon (Columba livia) to monitor anthropogenic debris in urban areas: a case study in Taiwan’s capital city

Wei-Ting Chen
Wen-Ta Yang
Hsiao-Wei Yuan
ResearchOpen Access18 Feb 2025
Scientific Reports

Volume: 15, P: 1-12
Overexpression of miR-370 and downregulation of its novel target TGFβ-RII contribute to the progression of gastric carcinoma

S-S Lo
P-S Hung
C-W Wu
Research13 Jun 2011
Oncogene

Volume: 31, P: 226-237
Vaccine-induced antigen-specific regulatory T cells attenuate the antiviral immunity against acute influenza virus infection

Pin-Hung Lin
Weng-In Wong
Hung-Chih Yang
Research21 Feb 2018
Mucosal Immunology

Volume: 11, P: 1239-1253
Location of Cerebral Microbleeds And Their Association with Carotid Intima-media Thickness: A Community-based Study

Chih-Ping Chung
Kun-Hsien Chou
Pei-Ning Wang
ResearchOpen Access21 Sept 2017
Scientific Reports

Volume: 7, P: 1-7
Cerebral small vessel disease phenotype and 5-year mortality in asymptomatic middle-to-old aged individuals

Wei-Ju Lee
Kun-Hsien Chou
Chih-Ping Chung
ResearchOpen Access30 Nov 2021
Scientific Reports

Volume: 11, P: 1-10
Composite diagnostic criteria are problematic for linking potentially distinct populations: the case of frailty

Yi-Sheng Chao
Chao-Jung Wu
Wei-Chih Chen
ResearchOpen Access13 Feb 2020
Scientific Reports

Volume: 10, P: 1-14
Using syndrome mining with the Health and Retirement Study to identify the deadliest and least deadly frailty syndromes

Yi-Sheng Chao
Chao-Jung Wu
Wei-Chih Chen
ResearchOpen Access08 Apr 2020
Scientific Reports

Volume: 10, P: 1-15

Search

Two dynamically competing factors determine the translation start site

Targeting MORF4L1-mediated DNA repair potentiates RT-induced antitumor immunity via cGAS-STING activation in hepatocellular carcinoma

Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair

Genome-scale long noncoding RNA expression pattern in squamous cell lung cancer

Data from multi-national aging cohorts show dysregulated metabolic pathways in people with physio-cognitive decline

Preoperative %p2PSA and Prostate Health Index Predict Pathological Outcomes in Patients with Prostate Cancer Undergoing Radical Prostatectomy

Using feral pigeon (Columba livia) to monitor anthropogenic debris in urban areas: a case study in Taiwan’s capital city

Overexpression of miR-370 and downregulation of its novel target TGFβ-RII contribute to the progression of gastric carcinoma

Vaccine-induced antigen-specific regulatory T cells attenuate the antiviral immunity against acute influenza virus infection

Location of Cerebral Microbleeds And Their Association with Carotid Intima-media Thickness: A Community-based Study

Cerebral small vessel disease phenotype and 5-year mortality in asymptomatic middle-to-old aged individuals

Composite diagnostic criteria are problematic for linking potentially distinct populations: the case of frailty

Using syndrome mining with the Health and Retirement Study to identify the deadliest and least deadly frailty syndromes

Search

Quick links

Search

Filter By:

Search

Quick links