Nature Search

Brain-wide input-output analysis of tuberal nucleus somatostatin neurons reveals hierarchical circuits for orchestrating feeding behavior

Neural circuit mechanisms underlying feeding behavior regulation are not fully understood. Here authors provide quantitative mapping of the brain-wide input and output configuration of tuberal nucleus somatostatin neurons, a key player of feeding regulation, in mouse brain for a deeper understanding of the feeding regulation network.

Esra Senol
Menghan Wang
Yu Fu
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-16
Cholesterol sensing by the SCAP–FAM134B complex regulates ER-phagy and STING innate immunity

The authors show that the endoplasmic reticulum-phagy receptor FAM134B interacts with SCAP to regulate cholesterol biosynthesis, sequestering SCAP when endoplasmic reticulum cholesterol is high but dissociating upon low cholesterol levels, allowing SCAP to activate cholesterol synthesis.

Boran Li
Dongheng Zhou
Qiming Sun
Research13 Oct 2025
Nature Cell Biology

Volume: 27, P: 1739-1756
Polymeric nanocarrier via metabolism regulation mediates immunogenic cell death with spatiotemporal orchestration for cancer immunotherapy

Cancer immunotherapy leans on the effective activation on immune response within tumors and surrounding immunosuppressive microenvironment. Here, the authors report a triblock copolymeric nanocarrier encapsulating Resiquimod for B16F10 cell-targeting, which enables in situ tumor vaccination and tumor-associated macrophages polarization.

Yichen Guo
Yongjuan Li
Weijing Yang
ResearchOpen Access04 Oct 2024
Nature Communications

Volume: 15, P: 1-20
Clinical efficacy and safety study of vNOTES for benign ovarian tumors in obese patients

Fei Wang
Yuqin Liu
Liehong Wang
ResearchOpen Access07 Feb 2025
Scientific Reports

Volume: 15, P: 1-6
Dual functions of microRNA-17 in maintaining cartilage homeostasis and protection against osteoarthritis

Osteoarthritic (OA) is characterized by progressive destruction of joint cartilage. Here, the authors show that microRNA-17 plays a dual role in maintaining cartilage homeostasis and in the prevention of osteoarthritis, by targeting hypoxia-inducible factor-1α as well as multiple matrix-degrading enzymes.

Yun Zhang
Shuaijun Li
Lei Cui
ResearchOpen Access04 May 2022
Nature Communications

Volume: 13, P: 1-14
Research on magnetic nonchain transport of steel cartridge casing ammunition

Jinyu Kang
Yongjuan Wang
ResearchOpen Access10 Oct 2024
Scientific Reports

Volume: 14, P: 1-11
Elucidating minimal residual disease of paediatric B-cell acute lymphoblastic leukaemia by single-cell analysis

Zhang et al. perform single-cell RNA and B-cell receptor sequencing to characterize the transcriptomic profiles of B-cell acute lymphoblastic leukaemia cells at diagnosis, residual and relapse stages, uncovering the hypoxia pathway as a potential target for residual leukaemia cells.

Yingchi Zhang
Shicheng Wang
Tao Cheng
Research10 Feb 2022
Nature Cell Biology

Volume: 24, P: 242-252
Peer pressure induced punishment resolves social dilemma on interdependent networks

Kaipeng Hu
Yewei Tao
Lei Shi
ResearchOpen Access04 Aug 2021
Scientific Reports

Volume: 11, P: 1-7
Mapping accumulated carbon storage of global mangroves from 2000 to 2020 at a 1 km resolution

Moran Wang
Tianyuan Zhang
Xudong Wu
ResearchOpen Access01 Apr 2025
Scientific Data

Volume: 12, P: 1-17
Golden opportunity for piRNA in female fertility

Mice deficient in the piRNA pathway display sterility only in males. Taking advantage of a more representative piRNA pathway in golden hamsters, three studies now demonstrate that the piRNA pathway is essential for fertility in hamsters of both sexes and thus strongly link this small RNA pathway to fertility regulation in both men and women.

Yongjuan Guan
P. Jeremy Wang
News & Views06 Sept 2021
Nature Cell Biology

Volume: 23, P: 936-938
Genetic correlation between fetal nuchal translucency thickening and cystic hygroma and exploration of pregnancy outcome

Jianli Zheng
Tiantian Wang
Jianbing Liu
ResearchOpen Access08 Nov 2024
Scientific Reports

Volume: 14, P: 1-10
Manganese transporter Slc39a14 deficiency revealed its key role in maintaining manganese homeostasis in mice

Yongjuan Xin
Hong Gao
Fudi Wang
ResearchOpen Access18 Jul 2017
Cell Discovery

Volume: 3, P: 1-13
A class III WRKY transcription factor in sugarcane was involved in biotic and abiotic stress responses

Dongjiao Wang
Ling Wang
Yachun Su
ResearchOpen Access01 Dec 2020
Scientific Reports

Volume: 10, P: 1-15
piR-823 inhibits cell apoptosis via modulating mitophagy by binding to PINK1 in colorectal cancer

Shuling Wang
Xiaoyu Jiang
Huiqing Jiang
ResearchOpen Access17 May 2022
Cell Death & Disease

Volume: 13, P: 1-14
The dual coding of a single sex pheromone receptor in Asian honeybee Apis cerana

Identifying HOB, a substance of the queen mandibular pheromone, as an anti-aphrodisiac in Asian honeybee chemical communication.

Haoqin Ke
Jonathan D. Bohbot
Yinliang Wang
ResearchOpen Access25 Apr 2024
Communications Biology

Volume: 7, P: 1-9
Retraction Note: Extracellular vesicle-associated microRNA-221-3p secreted by drug-resistant lung cancer cells targets HMBOX1 to promote the progression of lung cancer

Jun Li
Yongjuan Zhao
Jing Wang
Amendments and Corrections20 Jul 2021
Cancer Gene Therapy

Volume: 28, P: 1391
Sugarcane calcineurin B-like (CBL) genes play important but versatile roles in regulation of responses to biotic and abiotic stresses

Su Weihua
Huang Long
Que Youxiong
ResearchOpen Access13 Jan 2020
Scientific Reports

Volume: 10, P: 1-13
The alteration of RhoA geranylgeranylation and Ras farnesylation breaks the integrity of the blood–testis barrier and results in hypospermatogenesis

Ruilou Zhu
Jiangnan Wang
Chaojun Li
ResearchOpen Access06 Jun 2019
Cell Death & Disease

Volume: 10, P: 1-12
Refinery wastewater treatment via a multistage enhanced biochemical process

Chunhua Wang
Zijian Chen
Xiaofang Yang
ResearchOpen Access13 May 2021
Scientific Reports

Volume: 11, P: 1-11
RETRACTED ARTICLE: Extracellular vesicle-associated microRNA-221-3p secreted by drug-resistant lung cancer cells targets HMBOX1 to promote the progression of lung cancer

Jun Li
Yongjuan Zhao
Jing Wang
Research20 Nov 2020
Cancer Gene Therapy

Volume: 28, P: 679-692

Search

Brain-wide input-output analysis of tuberal nucleus somatostatin neurons reveals hierarchical circuits for orchestrating feeding behavior

Cholesterol sensing by the SCAP–FAM134B complex regulates ER-phagy and STING innate immunity

Polymeric nanocarrier via metabolism regulation mediates immunogenic cell death with spatiotemporal orchestration for cancer immunotherapy

Clinical efficacy and safety study of vNOTES for benign ovarian tumors in obese patients

Dual functions of microRNA-17 in maintaining cartilage homeostasis and protection against osteoarthritis

Research on magnetic nonchain transport of steel cartridge casing ammunition

Elucidating minimal residual disease of paediatric B-cell acute lymphoblastic leukaemia by single-cell analysis

Peer pressure induced punishment resolves social dilemma on interdependent networks

Mapping accumulated carbon storage of global mangroves from 2000 to 2020 at a 1 km resolution

Golden opportunity for piRNA in female fertility

Genetic correlation between fetal nuchal translucency thickening and cystic hygroma and exploration of pregnancy outcome

Manganese transporter Slc39a14 deficiency revealed its key role in maintaining manganese homeostasis in mice

A class III WRKY transcription factor in sugarcane was involved in biotic and abiotic stress responses

piR-823 inhibits cell apoptosis via modulating mitophagy by binding to PINK1 in colorectal cancer

The dual coding of a single sex pheromone receptor in Asian honeybee Apis cerana

Retraction Note: Extracellular vesicle-associated microRNA-221-3p secreted by drug-resistant lung cancer cells targets HMBOX1 to promote the progression of lung cancer

Sugarcane calcineurin B-like (CBL) genes play important but versatile roles in regulation of responses to biotic and abiotic stresses

The alteration of RhoA geranylgeranylation and Ras farnesylation breaks the integrity of the blood–testis barrier and results in hypospermatogenesis

Refinery wastewater treatment via a multistage enhanced biochemical process

RETRACTED ARTICLE: Extracellular vesicle-associated microRNA-221-3p secreted by drug-resistant lung cancer cells targets HMBOX1 to promote the progression of lung cancer

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