Visible light-curable alginate was prepared by coupling alginate with furfurylamine. The prepared furfuryl alginate (F-Alginate) underwent gelation in the presence of a photosensitizer under visible light irradiation. The mechanical and release properties of the visible light-induced gel were similar to that of conventional Ca2+-induced cross-linked alginate. The release rate of encapsulated substances depended on their molecular weight. Cell growth was enhanced in response to a sustained release of insulin-like growth factor-1 from the F-Alginate hydrogel.
- Yun Heo
- Jun Akimoto
- Yoshihiro Ito