Small-conductance Ca2+ -activated K+ (KCa2.1-KCa2.3) channels modulate neuronal and cardiac excitability. Here, authors report cryo-EM structures of the KCa2.2 channel, providing a basis for understanding the small unitary conductance and pharmacology of KCa2.x channels.
- Young-Woo Nam
- Dohyun Im
- Miao Zhang