Nature Search

Divergent sequences of tetraspanins enable plants to specifically recognize microbe-derived extracellular vesicles

Extracellular vesicles (EVs) are important in plant-microbe interactions. Here we show that the divergent sequences within tetraspanins localized at EV membranes enable plant innate immune system to distinguish between self and non-self EVs.

Jinyi Zhu
Qian Qiao
Yuanchao Wang
ResearchOpen Access12 Aug 2023
Nature Communications

Volume: 14, P: 1-14
Temporal evidence fusion evaluation method considering time sequence variation trend

Sunan Zhang
Yanxin Gao
Qichao Guo
ResearchOpen Access11 Jul 2025
Scientific Reports

Volume: 15, P: 1-9
The nuclear exosome co-factor MTR4 shapes the transcriptome for meiotic initiation

Nuclear RNA decay regulates gene expression in cultured cells, but its role in animals is largely unclear. Here, authors found that the nuclear exosome co-factor MTR4 functions in shaping the transcriptome for meiosis initiation and male fertility.

Li Zhang
Jianshu Wang
Hong Cheng
ResearchOpen Access17 Mar 2025
Nature Communications

Volume: 16, P: 1-19
Structural and functional brain alterations associated with pain in Parkinson’s disease

Erlei Wang
Yujing Jia
Guohua Fan
ResearchOpen Access21 Nov 2025
npj Parkinson's Disease

Volume: 11, P: 1-8
Author Correction: Reversing a model of Parkinson’s disease with in situ converted nigral neurons

Hao Qian
Xinjiang Kang
Xiang-Dong Fu
Amendments and Corrections29 Jul 2020
Nature

Volume: 584, P: E17
Unequal effects of climate intervention on agriculture

Model simulations show regional disparities in the responses of national crop productions to a suite of solar geoengineering scenarios that reflect sunlight to cool Earth.

Yuanchao Fan
News & Views05 Oct 2023
Nature Food

Volume: 4, P: 835-836
Rapid flips between warm and cold extremes in a warming world

Rapid temperature flips between hot and cold extremes will become more frequent, more intense, and more rapid globally by the end of the twenty-first century, which is exacerbated in world’s breadbasket regions and low-income countries.

Sijia Wu
Ming Luo
Tao Pei
ResearchOpen Access22 Apr 2025
Nature Communications

Volume: 16, P: 1-12
Oomycete plant pathogens: biology, pathogenesis and emerging control strategies

Oomycete plant pathogens are a serious global threat to crop production and food security. This Review outlines oomycete biology, diversity and lifestyle, discusses the disease cycle in plants, highlights pathogenicity mechanisms and the impact of oomycete plant pathogens, and considers emerging strategies for disease management.

Yan Wang
Francine Govers
Yuanchao Wang
Reviews28 Oct 2025
Nature Reviews Microbiology

Volume: 24, P: 270-287
Solar geoengineering can alleviate climate change pressures on crop yields

Rising temperatures are expected to have negative effects on agricultural production. Advanced crop and Earth system modelling indicate the degree to which technologies such as stratospheric aerosol injection, marine sky brightening and cirrus cloud thinning can help mitigate pressure on global crop yields.

Yuanchao Fan
Jerry Tjiputra
David Keith
Research20 May 2021
Nature Food

Volume: 2, P: 373-381
Separation and recovery of carbon powder in anodes from spent lithium-ion batteries to synthesize graphene

Li Yang
Liu Yang
Xiaobo Li
ResearchOpen Access08 Jul 2019
Scientific Reports

Volume: 9, P: 1-7
Divergent impacts of climate interventions on China’s north-south water divide

Equatorial stratospheric aerosol injection may mitigate north drought-south flood by reducing temperature gradients and altering circulation, which increases precipitation and runoff in northern China while reducing them in the south, according to analysis of the Norwegian Earth system model and volcanic data.

Xiao Zhang
Yuanchao Fan
Qiao Chen
ResearchOpen Access04 Sept 2025
Communications Earth & Environment

Volume: 6, P: 1-13
Reversing a model of Parkinson’s disease with in situ converted nigral neurons

Depletion of the RNA-binding protein PTB (also known as PTBP1) in astrocytes reprograms these cells to become functional neurons and, in a mouse model of Parkinson’s disease, reverses the disease phenotype.

Hao Qian
Xinjiang Kang
Xiang-Dong Fu
Research24 Jun 2020
Nature

Volume: 582, P: 550-556
New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Exploring the collision, acoustic and thermal energy dissipation distribution of discrete mass

Zhang Shengwu
Wang Chiming
Zhu Shunzhi
ResearchOpen Access20 Jul 2024
Scientific Reports

Volume: 14, P: 1-15
Widespread outdoor exposure to uncompensable heat stress with warming

Farmers and people collecting drinking water outside are projected to be at risk of not achieving sufficient heat dissipation to maintain a stable body temperature at 2 degrees Celsius of global warming, according to an analysis based on a physically based model and heat stress scenarios.

Yuanchao Fan
Kaighin A. McColl
ResearchOpen Access12 Dec 2024
Communications Earth & Environment

Volume: 5, P: 1-13
Global profiling of RNA-binding protein target sites by LACE-seq

Xue and colleagues developed LACE-seq to globally profile RNA targets of RNA-binding proteins at single-nucleotide resolution in low-input cells or even single oocytes.

Ruibao Su
Li-Hua Fan
Yuanchao Xue
Research09 Jun 2021
Nature Cell Biology

Volume: 23, P: 664-675
Wearable flexible microfluidic sensing technologies

Wearable flexible microfluidic sensors may enable health monitoring and disease diagnosis at the point of care. This Review discusses the integration of flexible microfluidics with wearable biosensors for the detection of clinically relevant analytes in biofluids.

Shuwen Chen
Zheng Qiao
Chwee Teck Lim
Reviews08 Sept 2023
Nature Reviews Bioengineering

Volume: 1, P: 950-971
Whole-genome variant of 220 Tibetan sheep from the Qinghai-Tibetan Plateau

Zengkui Lu
Chao Yuan
Jianbin Liu
ResearchOpen Access06 Dec 2025
Scientific Data

Volume: 13, P: 1-8
Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model

Ruxue Zhang
Yumin Zhang
Leike Zhang
ResearchOpen Access16 Apr 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-3
Interstitial fluid-based wearable biosensors for minimally invasive healthcare and biomedical applications

There is growing interest in biosensors that detect biomarkers in interstitial fluid. This Review provides an overview of recent developments on interstitial fluid biosensors, including device fabrication and sensing mechanisms, and outstanding challenges faced.

Zixiong Wu
Zheng Qiao
Chwee Teck Lim
ReviewsOpen Access13 Mar 2024
Communications Materials

Volume: 5, P: 1-15

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