It is currently challenging to identify the Blood-brain barrier (BBB) status using non-contrast MR images due to lack of gadolinium-based contrast agents (GBCA)-induced features. Here the authors find that the contrast-free BBB status identification model (CBSI) overcomes such limitations due to its ability to perform comparably to the gadolinium-enhanced T1-weighted (T1Gd) magnetic resonance (MR) model as well as its generalizability potential.
- Kaiyi Zheng
- Yiwen Zhang
- Liming Zhong
