The authors present phase intensity nanoscope (PINE), which uses an integrated phase-intensity multilayer thin film to localize randomly distributed nanoprobes and resolve sub-10 nm cellular architectures. They demonstrate dynamic imaging of nanoscopic reorganization over 250 h and find that nanoscale rearrangements emerging into macroscale rearrangements are synchronized.
- Guangjie Cui
- Yunbo Liu
- Somin Eunice Lee