Nature Search

Molecular characterization and prognostic implications of KRAS mutations in pancreatic cancer patients: insights from multi-cohort analysis

Yubo Jiang
Gang Mai
Huirong Xu
ResearchOpen Access22 Aug 2025
npj Precision Oncology

Volume: 9, P: 1-11
METTL3 safeguards cell identity and epigenome of human trophoblast stem cells

METTL3 promotes healthy placenta function by regulating m⁶A methylation and histone epigenetics. Deficiency in METTL3 leads to premature senescence, inflammation activation of trophoblasts, contributing to pregnancy complications like preeclampsia.

Haifeng Fu
Chunxiao Chen
Pentao Liu
ResearchOpen Access16 Dec 2025
Nature Communications

Volume: 17, P: 1-19
Abiotic N₂ reduction in submarine hydrothermal systems could quickly fertilize prebiotic oceans

This study investigates samples drilled from the ocean floor and finds that that mineral reduction of N₂ could have produced abundant ammonium to fertilize Earth’s early oceans to support a habitable environment for the origin and evolution of life.

Liheng Sun
Kan Li
Long Li
ResearchOpen Access28 Nov 2025
Nature Communications

Volume: 16, P: 1-10
Leukocyte CH25H is a potential diagnostic and prognostic marker for lung adenocarcinoma

Jun Zhang
Lidong Xu
Daoyun Zhang
ResearchOpen Access23 Dec 2022
Scientific Reports

Volume: 12, P: 1-9
Hydrogen-bonded organic framework@conductive metal-organic framework heterostructures for ampere-level hydrogen peroxide production

Industrial-level electrochemical two-electron oxygen reduction reaction is promising for H₂O₂ production but lacks efficient catalysts. Here, the authors design a heterostructure catalyst for efficient H₂O₂ electrosynthesis at ampere-level current densities.

Yingying Zou
Yulin Zhang
Chengzhong Yu
ResearchOpen Access04 Dec 2025
Nature Communications

Volume: 16, P: 1-11
Hypoxic preconditioning accelerates the healing of ischemic intestinal injury by activating HIF-1α/PPARα pathway-mediated fatty acid oxidation

Linxia Li
Yanqi Liu
Yunying Wang
ResearchOpen Access04 Apr 2024
Cell Death Discovery

Volume: 10, P: 1-9
Insights from indoor testing and numerical simulations of the Lanniqing Landslide in Zhaotong, Yunnan Province, China

Xu Zongheng
Chen Yunying
ResearchOpen Access31 Oct 2025
Scientific Reports

Volume: 15, P: 1-15
Stable and high-yield hydrogen peroxide electrosynthesis from seawater

Hydrogen peroxide (H₂O₂) is a green oxidant with diverse applications. Aided by a nickel phosphorus trisulfide nanosheet electrocatalyst, this work shows a sustainable synthetic route to produce H₂O₂ from seawater with high yield and impressive stability.

Chaoqi Zhang
Pengyue Shan
Chengzhong Yu
Research01 Apr 2025
Nature Sustainability

Volume: 8, P: 542-552
Single cell immunoprofile of synovial fluid in rheumatoid arthritis with TNF/JAK inhibitor treatment

Inflammatory immune cells are found in the synovial fluid of patients with rheumatoid arthritis (RA). Here the authors use scRNA sequencing of synovial fluid cells from RA patients before and after treatment with adalimumab/tofacitinib and find changes in inflammatory SPP1+ macrophages and explore the function of these cells in mouse models.

Xuyang Xia
Chenjia He
Qibing Xie
ResearchOpen Access04 Mar 2025
Nature Communications

Volume: 16, P: 1-23
Isolation and Characterization of Antibiotic NC0604, a New Analogue of Bleomycin

Caixia Chen
Shuyi Si
Ruxian Chen
Research01 Dec 2008
The Journal of Antibiotics

Volume: 61, P: 747-751
ZC3H12D gene expression exhibits dual effects on the development and progression of lung adenocarcinoma

Yuansi Zheng
Yuhuan Zhang
Ying Su
ResearchOpen Access18 May 2025
Scientific Reports

Volume: 15, P: 1-12
The PM20D1-NADA pathway protects against Parkinson’s disease

Yunying Yang
Sichun Chen
Zhentao Zhang
Research22 Aug 2024
Cell Death & Differentiation

Volume: 31, P: 1545-1560
Knowledge, attitudes, and practices regarding home-based cardiac rehabilitation in patients with chronic heart failure

Wumei Xia
Li Huang
Ting Liu
ResearchOpen Access23 Aug 2025
Scientific Reports

Volume: 15, P: 1-10
Deciphering the pharmacological mechanism of Radix astragali for allergic rhinitis through network pharmacology and experimental validation

Yiwei Hua
Xi Tan
Yunying Li
ResearchOpen Access02 Dec 2024
Scientific Reports

Volume: 14, P: 1-15
Epiconone, one novel cyclohexenone from endophytic fungi Epicoccum sp. 1-042

Shanshan Chang
Xinyue Huang
Yunying Xie
Research07 Mar 2025
The Journal of Antibiotics

Volume: 78, P: 330-335
A phase 2 pilot study of umbilical cord blood infusion as an adjuvant consolidation therapy in elderly patients with acute myeloid leukemia

Jinzeng Wang
Xiaoyang Li
Ruibao Ren
ResearchOpen Access20 Dec 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-10
GKK1032C, a new alkaloid compound from the endophytic fungus Penicillium sp. CPCC 400817 with activity against methicillin-resistant S. aureus

Xin Qi
Xiaoqian Li
Yunying Xie
Research08 Feb 2019
The Journal of Antibiotics

Volume: 72, P: 237-240
Accounting for differences between crops and regions reduces estimates of nitrate leaching from nitrogen-fertilized soils

Almost half of globally leached nitrate from nitrogen-fertilized soil is released in China, India, and the United States, according to a meta-analysis covering 2500 field observations worldwide.

Yan Wang
Yihong Liu
Yanjiang Cai
ResearchOpen Access16 Jan 2025
Communications Earth & Environment

Volume: 6, P: 1-12
Pulsed electromagnetic fields regulate metabolic reprogramming and mitochondrial fission in endothelial cells for angiogenesis

Chengyi Yang
Li Xu
Huifang Liu
ResearchOpen Access16 Aug 2024
Scientific Reports

Volume: 14, P: 1-12
Precursor-directed biosynthesis of new sansanmycin analogs bearing para-substituted-phenylalanines with high yields

Ningning Zhang
Li Liu
Ruxian Chen
Research24 Feb 2016
The Journal of Antibiotics

Volume: 69, P: 765-768
NUDT21 negatively regulates PSMB2 and CXXC5 by alternative polyadenylation and contributes to hepatocellular carcinoma suppression

Sheng Tan
Hua Li
Tao Zhu
Research21 May 2018
Oncogene

Volume: 37, P: 4887-4900
Exosomal miR-143-3p derived from follicular fluid promotes granulosa cell apoptosis by targeting BMPR1A in polycystic ovary syndrome

Yuanyuan Zhao
Shuhong Pan
Xiaohua Wu
ResearchOpen Access14 Mar 2022
Scientific Reports

Volume: 12, P: 1-12
Tillage and nitrogen fertilization enhanced belowground carbon allocation and plant nitrogen uptake in a semi-arid canola crop–soil system

Jharna Rani Sarker
Bhupinder Pal Singh
Annette L. Cowie
ResearchOpen Access06 Sept 2017
Scientific Reports

Volume: 7, P: 1-13

Search

Molecular characterization and prognostic implications of KRAS mutations in pancreatic cancer patients: insights from multi-cohort analysis

METTL3 safeguards cell identity and epigenome of human trophoblast stem cells

Abiotic N₂ reduction in submarine hydrothermal systems could quickly fertilize prebiotic oceans

Leukocyte CH25H is a potential diagnostic and prognostic marker for lung adenocarcinoma

Hydrogen-bonded organic framework@conductive metal-organic framework heterostructures for ampere-level hydrogen peroxide production

Hypoxic preconditioning accelerates the healing of ischemic intestinal injury by activating HIF-1α/PPARα pathway-mediated fatty acid oxidation

Insights from indoor testing and numerical simulations of the Lanniqing Landslide in Zhaotong, Yunnan Province, China

Stable and high-yield hydrogen peroxide electrosynthesis from seawater

Single cell immunoprofile of synovial fluid in rheumatoid arthritis with TNF/JAK inhibitor treatment

Isolation and Characterization of Antibiotic NC0604, a New Analogue of Bleomycin

ZC3H12D gene expression exhibits dual effects on the development and progression of lung adenocarcinoma

The PM20D1-NADA pathway protects against Parkinson’s disease

Knowledge, attitudes, and practices regarding home-based cardiac rehabilitation in patients with chronic heart failure

Deciphering the pharmacological mechanism of Radix astragali for allergic rhinitis through network pharmacology and experimental validation

Epiconone, one novel cyclohexenone from endophytic fungi Epicoccum sp. 1-042

A phase 2 pilot study of umbilical cord blood infusion as an adjuvant consolidation therapy in elderly patients with acute myeloid leukemia

GKK1032C, a new alkaloid compound from the endophytic fungus Penicillium sp. CPCC 400817 with activity against methicillin-resistant S. aureus

Accounting for differences between crops and regions reduces estimates of nitrate leaching from nitrogen-fertilized soils

Pulsed electromagnetic fields regulate metabolic reprogramming and mitochondrial fission in endothelial cells for angiogenesis

Precursor-directed biosynthesis of new sansanmycin analogs bearing para-substituted-phenylalanines with high yields

NUDT21 negatively regulates PSMB2 and CXXC5 by alternative polyadenylation and contributes to hepatocellular carcinoma suppression

Exosomal miR-143-3p derived from follicular fluid promotes granulosa cell apoptosis by targeting BMPR1A in polycystic ovary syndrome

Tillage and nitrogen fertilization enhanced belowground carbon allocation and plant nitrogen uptake in a semi-arid canola crop–soil system

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