The synthesis of α,β-stereogenic tertiary alcohols featuring multiple contiguous stereocentres is a challenge. Now, a method for the enantioconvergent copper-catalysed allylation, propargylation and crotylation of racemic ketones is reported. The process provides access to chiral tertiary alcohols bearing multiple contiguous stereocentres.
- Bo Sun
- Lin-Xin Ruan
- Shi-Liang Shi
