Nature Search

Arabidopsis IONIC CURRENT FAMILY A proteins facilitate environmental calcium acquisition essential for stress tolerance

This study identifies ICA proteins in Arabidopsis roots as key mediators of Ca²⁺ uptake through non-selective cation channels. High-order ica mutants show reduced Ca²⁺ levels and heightened stress sensitivity, revealing ICAs’ role in Ca²⁺ homeostasis.

Zhijie Ren
Zebin Liu
Wang Tian
Research05 Jan 2026
Nature Plants

Volume: 12, P: 125-139
A lung CT vision foundation model facilitating disease diagnosis and medical imaging

Lung CT imaging and artificial intelligence are increasingly integral to modern patient care. Here, the authors show LCTfound, a vision foundation model, which employs diffusion-based pretraining to enable a wide range of downstream applications.

Zebin Gao
Guoxun Zhang
Qionghai Dai
ResearchOpen Access03 Dec 2025
Nature Communications

Volume: 17, P: 1-17
Plasma membrane CYBDOM proteins catalyse apoplastic AsA regeneration and interact with RbohD to activate autophagy and drought tolerance in plants

This study reveals that CYBDOM proteins promote drought tolerance by regenerating apoplastic ascorbic acid (AsA) and activating autophagy through interaction with RbohD, and link AsA redox, ROS and selective autophagy in plant stress responses

Xiuxiu Chen
Songsong Jin
Xin Deng
Research01 Aug 2025
Nature Plants

Volume: 11, P: 1681-1699
Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge

G-quadruplexes (G4s) are stable structures that can disrupt genome stability and are dissolved by helicases. Here the authors present the structure of the yeast helicase Pif1 bound to a G4 and reveal a conserved G4 interacting region.

Zebin Hong
Alicia K. Byrd
Haiwei Song
ResearchOpen Access19 Jul 2024
Nature Communications

Volume: 15, P: 1-13
Mechanism of nucleosomal H2A K13/15 monoubiquitination and adjacent dual monoubiquitination by RNF168

Using site-specific chemical crosslinking strategies, Ai, Tong and Deng et al. captured structural intermediates of ubiquitin E3 ligase RNF168-mediated H2A K13 and K15 monoubiquitination and adjacent dual monoubiquitination in the DNA damage repair response; the structural analysis revealed a helix-anchoring mechanism.

Huasong Ai
Zebin Tong
Man Pan
Research11 Oct 2024
Nature Chemical Biology

Volume: 21, P: 668-680
Hematopoietic stem and progenitor cell membrane-coated vesicles for bone marrow-targeted leukaemia drug delivery

Effective delivery of drugs to bone marrow has potential for leukemia treatment. Here the authors report the delivery of chemotherapy drug Ara-C with HSPC cell membrane derived-biomimetic vesicles, which target leukemia stem cells thereby effectively inhibit its progression.

Jinxin Li
Honghui Wu
Pengxu Qian
ResearchOpen Access07 Jul 2024
Nature Communications

Volume: 15, P: 1-17
Multi-omic characterization of allele-specific regulatory variation in hybrid pigs

Here, the authors use multi-omic data to reveal how genetic and epigenetic variation affects gene expression in two pig breeds. The findings highlight strong tissue-specific regulation and identify genes with allele-specific expression.

Jianping Quan
Ming Yang
Zhenfang Wu
ResearchOpen Access03 Jul 2024
Nature Communications

Volume: 15, P: 1-18
How to improve the effectiveness of the cooperation networks of emergency science communication for public health emergencies

Jida Liu
Zheng Fu
Zebin Zhao
ResearchOpen Access31 Oct 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-15
Changes in the assembly and functional adaptation of endophytic microbial communities in Amorphophallus species with different levels of resistance to necrotrophic bacterial pathogen stress

A study on the response of different resistant Amorphophallus species to Pcc stress reveals that endophytic fungal taxa play a key role in host plant’s defense against necrotizing bacterial pathogens.

Min Yang
Ying Qi
Lei Yu
ResearchOpen Access19 May 2025
Communications Biology

Volume: 8, P: 1-16
Functional dynamics analysis of endophytic microbial communities during Amorphophallus muelleri seed maturation

Min Yang
Yongteng Zhao
Lei Yu
ResearchOpen Access18 Nov 2024
Scientific Reports

Volume: 14, P: 1-12
Blocking TBK1 alleviated radiation-induced pulmonary fibrosis and epithelial-mesenchymal transition through Akt-Erk inactivation

Hongjin Qu
Lei Liu
Jianming Cai
ResearchOpen Access15 Apr 2019
Experimental & Molecular Medicine

Volume: 51, P: 1-17
Edoxaban for stroke prevention in atrial fibrillation and factors associated with dosing: patient characteristics from the prospective observational ETNA-AF-China registry

Xueyuan Guo
Juan Du
Jian Zhang
ResearchOpen Access02 Feb 2024
Scientific Reports

Volume: 14, P: 1-15

Search

Arabidopsis IONIC CURRENT FAMILY A proteins facilitate environmental calcium acquisition essential for stress tolerance

A lung CT vision foundation model facilitating disease diagnosis and medical imaging

Plasma membrane CYBDOM proteins catalyse apoplastic AsA regeneration and interact with RbohD to activate autophagy and drought tolerance in plants

Eukaryotic Pif1 helicase unwinds G-quadruplex and dsDNA using a conserved wedge

Mechanism of nucleosomal H2A K13/15 monoubiquitination and adjacent dual monoubiquitination by RNF168

Hematopoietic stem and progenitor cell membrane-coated vesicles for bone marrow-targeted leukaemia drug delivery

Multi-omic characterization of allele-specific regulatory variation in hybrid pigs

How to improve the effectiveness of the cooperation networks of emergency science communication for public health emergencies

Changes in the assembly and functional adaptation of endophytic microbial communities in Amorphophallus species with different levels of resistance to necrotrophic bacterial pathogen stress

Functional dynamics analysis of endophytic microbial communities during Amorphophallus muelleri seed maturation

Blocking TBK1 alleviated radiation-induced pulmonary fibrosis and epithelial-mesenchymal transition through Akt-Erk inactivation

Edoxaban for stroke prevention in atrial fibrillation and factors associated with dosing: patient characteristics from the prospective observational ETNA-AF-China registry

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