Wei, Bai, Wang, and colleagues present HypnoS, a genetically-encoded fluorescent sensor for the real-time monitoring of intracellular adenosine (iAdo) in a cell type-specific manner. They monitor iAdo dynamics during seizures or sleep-wake cycles with high spatiotemporal resolution in the brain of living animals.
- Qingpeng Wei
- Zexiao Bai
- Jing Wang