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Showing 1–7 of 7 results

Advanced filters: Author: Zhiyun Gu Clear advanced filters

APOE–NOTCH axis governs elastogenesis during human cardiac valve remodeling

Z. Liu, Y. Liu and Z. Yu et al. discovered a subtype of valve interstitial cells underneath the valve endothelial cells sensing unidirectional flow. These cells express high levels of APOE, which is responsible for JAG1–NOTCH2-mediated fetal elastogenesis.

Ziyi Liu
Yu Liu
Mingxia Gu
Research24 Jul 2024
Nature Cardiovascular Research

Volume: 3, P: 933-950
Bioorthogonal optimized virus immuno-nanomedicine (BOVIN)

Recent research has indicated that cancer patients infected with respiratory viruses exhibit a positive antitumor response. This group develops a bioorthogonal optimized nonpathogenic-recombinant virus for targeted therapy of solid tumors.

Wenchang Peng
Yajing Du
Xingcai Zhang
ResearchOpen Access25 Nov 2025
Nature Communications

Volume: 17, P: 1-18
MEF2D-expressing cancer precursors reprogram tissue-resident macrophages to support liver tumorigenesis

Qian and colleagues show that MEF2D⁺ cancer precursors reprogram liver-resident Kupffer cells to create a microenvironment supporting liver tumorigenesis.

Junyu Xiang
Yuanli Ni
Cheng Qian
Research23 Oct 2025
Nature Cancer

Volume: 6, P: 1955-1975
Accelerated discovery of molecular nanojunction photocatalysts for hydrogen evolution by using automated screening and flow synthesis

An efficient molecular nanojunction photocatalyst for hydrogen evolution is identified from a combinatorial molecular library, assisted by a materials acceleration platform, which is then scaled-up to the litre scale using flow synthesis.

Weiwei Zhang
Miaojie Yu
Andrew I. Cooper
ResearchOpen Access08 Mar 2024
Nature Synthesis

Volume: 3, P: 595-605
ECM1 controls T_H2 cell egress from lymph nodes through re-expression of S1P₁

T_H2 cells are important for allergic and antiparasitic responses. Sun and colleagues demonstrate highly selective expression of the ECM1 protein in T_H2 cells and a key role for it in regulating migration.

Zhenhu Li
Yuan Zhang
Bing Sun
Research09 Jan 2011
Nature Immunology

Volume: 12, P: 178-185
Development and evaluation of cepharanthine-β-cyclodextrin inclusion complex oral tablets for prevention and treatment of COVID-19 lung injury

Di Liang
Zihan Lv
Guifang Dou
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-16
Neuroimaging evidence of glymphatic system dysfunction in possible REM sleep behavior disorder and Parkinson’s disease

Xiaoli Si
Tao Guo
Baorong Zhang
ResearchOpen Access29 Apr 2022
npj Parkinson's Disease

Volume: 8, P: 1-9