Nature Search

The serum platelet-to-lymphocyte ratio as a predictor of outcomes in bladder cancer patients: an updated meta-analysis

Baining Zhang
Zhuoyue Yao
Yong Zhang
ResearchOpen Access11 Nov 2025
Scientific Reports

Volume: 15, P: 1-12
Enhancing diagnostic accuracy in rare and common fundus diseases with a knowledge-rich vision-language model

Previous ophthalmic foundation models have struggled to generalize effectively to diverse and rare fundus diseases, restricting their clinical applicability. Here, the authors introduce a vision-language foundation model that demonstrates superior performance in diagnosing both common and rare fundus conditions.

Meng Wang
Tian Lin
Huazhu Fu
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-17
Stable isotope labelling to elucidate ring cleavage mechanisms of disinfection by-product formation during chlorination of phenols

The pathways by which aromatic compounds transform into acyclic by-products in chlorinated waters have important implications for water treatment and public health. Ethyl parabens with stable isotope labels at different carbon positions yield insights into how aromatic compounds can transform into lower-molecular-weight disinfection by-products.

Zhuoyue Zhang
Keith P. Reber
Carsten Prasse
Research09 Jan 2025
Nature Water

Volume: 3, P: 222-230
Elucidation of the noncovalent interactions driving enzyme activity guides branching enzyme engineering for α-glucan modification

In this work, the authors decipher the noncovalent interactions of branching enzymes (BE) with polysaccharides that drive enzyme activity, and report mechanism-guided engineering avenues to promote further development of these industrially important BEs.

Zhiyou Zong
Xuewen Zhang
Yuanxia Sun
ResearchOpen Access09 Oct 2024
Nature Communications

Volume: 15, P: 1-12
Reprogramming mechanism dissection and trophoblast replacement application in monkey somatic cell nuclear transfer

Somatic cloning of rhesus monkey has not been successful until now. Here, authors report epigenetic abnormalities in SCNT embryos and placentas and develop a trophoblast replacement method that enables them to successful clone of a healthy male rhesus monkey.

Zhaodi Liao
Jixiang Zhang
Qiang Sun
ResearchOpen Access16 Jan 2024
Nature Communications

Volume: 15, P: 1-18
Microwave-assisted biorefineries

Biorefineries can provide biofuels and bio-based materials to replace fossil fuels in chemical and energy production. This Review explores how microwaves can improve biorefinery performance and outlines the steps taken to translate this approach towards industrial applications.

Qiaozhi Zhang
Zhuo Li
Iris K. M. Yu
Reviews24 Feb 2025
Nature Reviews Clean Technology

Volume: 1, P: 269-287
Triggering of endoplasmic reticulum stress via ATF4-SPHK1 signaling promotes glioblastoma invasion and chemoresistance

Beiwu Lan
Zhoudao Zhuang
Yufei Gao
ResearchOpen Access01 Aug 2024
Cell Death & Disease

Volume: 15, P: 1-13
Spotlight on mechanism of sudden unexpected death in epilepsy in Dravet syndrome

WeiHui Shao
Lu Liu
HongHai Zhang
ReviewsOpen Access17 Mar 2025
Translational Psychiatry

Volume: 15, P: 1-17
Challenges and future directions of SUDEP models

This Review provides a comprehensive overview of several available animal models of sudden unexpected death in epilepsy (SUDEP), highlighting their pros and cons to elucidate SUDEP causes and mechanisms.

JiaXuan Gu
WeiHui Shao
HongHai Zhang
Reviews26 Aug 2024
Lab Animal

Volume: 53, P: 226-243

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