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This PrimeView highlights the mechanisms of bullous pemphigoid and summarizes the epidemiology, diagnosis and management of this disease. It accompanies the Primer article on this topic by Akbarialiabad et al.
Bullous pemphigoid is an autoimmune skin disease characterized by tense blisters and erosions. In this Primer, Akbarialiabad et al. review the epidemiology, pathophysiology, diagnosis and management of this disease, and highlight the quality of life of patients and future research areas.
Osteoarthritis, a complex, heterogeneous disease that affects an entire joint, including the bone, cartilage, ligaments and muscles, that is a leading cause of disability and premature work loss.
Osteoarthritis is a complex, multifactorial disorder affecting the entire joint that can cause pain and is a leading cause of disability and premature work loss. In this Primer, Tang and colleagues summarize the epidemiology, pathophysiology, diagnosis and management of osteoarthritis and highlight the global burden of the disease.
This PrimeView highlights the pathophysiology of chronic kidney disease and summarizes the epidemiology, diagnosis and management of this disease. It accompanies the Primer article on this topic by Romagnani et al.
Chronic kidney disease is the progressive and irreversible loss of kidney function. In this Primer, Romagnani et al. describe the epidemiology and pathophysiology of this disease, and summarize its diagnosis and management, explaining how understanding and treating all modifiable risk factors can slow the progression of chronic kidney disease and prevent or attenuate its consequences.
This PrimeView highlights the mechanisms underlying Cushing syndrome, and summarizes the epidemiology, diagnosis and management of this disorder. It accompanies the Primer article on this topic by Nieman et al.
Cushing syndrome (CS) is defined by signs and symptoms caused by hypercortisolism. In this Primer, Nieman and colleagues outline the causes of endogenous CS and discuss epidemiology, pathophysiology, diagnosis and management of different aetiologies of endogenous CS.
This PrimeView highlights the mechanisms underlying hereditary haemorrhagic telangiectasia, and summarizes the epidemiology, diagnosis and management of this disorder. It accompanies the Primer article on this topic by Hermann et al.
Hereditary haemorrhagic telangiectasia (HHT) is a rare genetic disorder that causes vascular anomalies. In this Primer, Hermann et al. review the epidemiology, pathophysiology, diagnosis, management and quality of life of individuals with HHT, as well as highlighting the unmet needs in the field.
