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Breeding crops with delayed senescence could plausibly increase grain yield. Here the authors show that variation at the rice SGR locus contributes to differences in senescence between indica and japonica subspecies and show that introgression can increase yield in an elite indica rice variety.

Motion tracking systems for virtual reality are challenged in tracking and feedback capabilities. Here, the authors report a wearable sensor-haptic network capturing full-body motion and delivering real-time bidirectional feedback, while deep learning integration enables low-latency, accurate classification.

The dietary fibre inulin is shown to promote fructose catabolism by the small intestinal microbiome, thereby mitigating fructose-induced hepatic lipogenesis and steatosis.

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Accurate segmentation of ischemic stroke lesions from brain MRI is crucial for timely diagnosis and treatment planning. Here, the authors present DeepISLES, an AI ensemble for stroke MRI analysis that outperforms previous methods and matches expert radiologist performance in identifying stroke lesions.

Aging impairs muscle and bone health, and exercise is known to mitigate this decline, partly through secreted factors. Here, the authors show that the muscle-derived factor CLCF1, which declines with age but is restored by exercise, mediates musculoskeletal benefits in aged mice.

Spinons, or fractionalized collective excitations, have been reported in 1D systems but are debated in higher dimensions. Here the authors show that a heterostructure-based approach induces liquid-like spin dynamics in a 2D Heisenberg antiferromagnet, with isotropic continuum excitations extending to low energies.

New two-dimensional semiconductors may exhibit properties beyond inherent semiconducting attributes. Here the authors report protonated semiconducting III–V-derived van der Waals crystals with memristive properties.

Ultrathin film photovoltaic cells are a promising energy device, but suffer from low power conversion efficiency. Here, the authors construct a double-junction tandem cell using a hydrogenated amorphous silicon and a polymer as the front and back cell, respectively, which achieves 10.5% efficiency.

Although quantum fluctuations of the spins occur on a local scale, they can have a macroscopic impact on the properties of magnets. Here, the authors observe the macroscopic influence of magnetic quantum fluctuations on the dielectric properties of a multiferroic oxide.

Combining frequency combs and plasmonics promises highly precise timing and frequency standards in nanoscale devices. Here, the authors experimentally transfer a frequency comb to surface plasmons and then return it to its original comb form with little degradation.

The synthesis of sequence-regulated oligosulfates has not yet been established due to the difficulties in precise reactivity control. Here, the authors report a multi-directional divergent iterative method to furnish oligosulfates based on a chain homologation approach, in which the fluorosulfate unit is regenerated.

Atomic structural changes in nanocrystals are still poorly understood. Here, the authors introduce time-resolved Brownian tomography to directly detect 3D atomic changes in Pt nanocrystals during oxidative etching and reveal disorder at sizes of ≈1 nm.

Combined experiment and modeling show that thermal fluctuations of protruding edge functional groups of graphene nanopores modulate the pore size, enabling thermally-activated molecular transport for high-temperature hydrogen separation.

Previous work has shown the existence of spin-orbit-entangled excitons and their coupling to antiferromagnetism in the correlated insulator NiPS₃. Here the authors show that non-equilibrium driving of these excitons produces a transient metallic antiferromagnetic state that cannot be achieved by tuning the temperature in equilibrium.

Wireless bioresorbable stimulators are promising therapeutic implants that naturally dissolve after use. Here, the authors developed a device that operates for months and enables simultaneous multi-site stimulation, preventing early muscle atrophy and accelerating reinnervation in nerve injury models.

Carbonic anhydrase (CA) mimics have promising applications in the enhanced hydration and sequestration of CO₂, but limited success has so far been achieved. Here, the authors report the assembly of sequence-defined peptoids into crystalline nanomaterials with controlled microenvironment of active sites as CA mimics for promoted hydration and sequestration of CO₂.

Spin-orbit effects at heavy metal/ferromagnet interfaces can give rise to the Dzyaloshinskii-Moriya interaction, promoting chiral magnetization textures applicable in thin film devices. Here, the authors use Brillouin light scattering to study the dependence of this interaction on film thickness.

Using well-calibrated statistical methods the authors jointly analyze Undiagnosed Diseases Network genomes, identifying known and novel disease genes. Software is publicly available to support future cross-cohort rare disease discovery efforts.

Only two types of neutral homo-calix compounds, including analogues, have been reported. Chun et al. now describe a new class of positively charged calix[n]imidazolium, which is synthesized in one pot and is able to recognize anions and fullerenes in aqueous media.

Here the authors developed on-chip microresonators with a remarkable Q-factor of 38 million and demonstrated on-chip Brillouin lasing in the mid-infrared. These results highlight opportunities to create more compact and efficient platforms for molecular science.

Isoprene emissions are commonly estimated using satellite measurements and model simulations. Here, using eddy covariance, the authors report higher emission rates over the Amazon forest than those estimated with these techniques and a relationship between terrain elevation and isoprene emissions.

Sensors based on localized surface plasmon resonance suffer from low figures of merit. Here, the authors achieve high refractive index sensitivities and figures of merit by introducing a chiral shape and the idea of engineering the material dispersion function.

Chun et al. find that a severe model of reactive astrocytes overproduces hydrogen peroxide, leading to the development of Alzheimer’s disease-like pathologies, including neurodegeneration, tauopathy and memory impairment.

The selectivity of a catalytic reaction is manipulated by straining a polymer support to which the catalyst is covalently bound. Enantioselective rhodium-catalysed hydrogenation of a series of 2-acetamidoacrylates is shown to increase with macroscopic strain, with enantiomeric ratios reaching twice their initial values.

Van der Waals materials can exhibit strong coupling between the lattice and other degrees of freedom. Here, Ergeçen et al reveal the presence of bound states emerging from the strong interaction between the lattice vibrations and d-orbitals in the van der Waals antiferromagnet NiPS₃.

Researchers demonstrate that PBDTT-DPP, a semiconducting polymer with a low bandgap of 1.44 eV, allows tandem polymer solar cells to reach power conversion efficiencies of around 8.6%.

Artificial muscles composed of carbon nanotube yarns have previously demonstrated fast, large-angle rotations. Here, the authors infiltrate carbon nanotube yarns with a paraffin wax and polystyrene-based copolymer mixture, achieving stable 9,800 r.p.m. rotation without apparent oscillation.

In two studies from teams led by Hiroshi Kawaguchi and Jang-Soo Chun, a role for HIF-2α in osteoarthritis has been uncovered. Along with identifying the molecular mechanism, the teams found that HIF-2α expression is increased in human osteoarthritic tissue, and mice deficient for the protein are protected in two osteoarthritis models, suggesting that HIF-2A could be a therapeutic target.

A tactile sensing system that can learn to identify different types of surface can be created using sensors that mimic the fast and slow responses of mechanoreceptors found in human skin.

Femtosecond X-ray liquidography is used to track the vibrational wavepacket trajectories of gold atoms in solution, enabling time-resolved observations of the emergence of vibrations and the evolution of the formation of covalent bonds.

A metastable palladium hydride is synthesized where the unique environment in the liquid cell, namely the limited quantity of Pd precursors and the continuous supply of H, resulted in the formation of the hcp phase.

Although artificial skins can facilitate the healing of damaged skin, the restoration of tactile functions remain a challenge. Here, Kang et al. report an artificial skin with an implantable tactile sensor that can simultaneously replace the tactile function by nerve stimulation and promote skin regeneration.

IgE is a critical component of the allergic response and therapeutic targeting can alleviate symptomology. Here the authors propose the combined use of Bifidobacterium longum and a FcεRIα extracellular domain linked to a IgD/IgG4 hybrid Fc domain fusion protein called IgE_TRAP and show reduction of mast cell and IgE levels in models of food allergy.