Nature Search

Nature of the Defect in Alcaptonuria

V. G. ZANNONI
J. E. SEEGMILLER
B. N. La DU
Research10 Mar 1962
Nature

Volume: 193, P: 952-953
Nature and Origin of Initial Bodies in Lymphogranuloma Venereum

J. A. ARMSTRONG
SYLVIA E. REED
Research25 Jan 1964
Nature

Volume: 201, P: 371-373
Population-specific polygenic risk scores for people of Han Chinese ancestry

The Taiwan Precision Medicine Initiative recruited and genotyped more than half a million Taiwanese participants, almost all of Han Chinese ancestry, and performed comprehensive genomic analyses and developed polygenic risk score prediction models for numerous health conditions.

Hung-Hsin Chen
Chien-Hsiun Chen
Cathy S. J. Fann
ResearchOpen Access15 Oct 2025
Nature

P: 1-10
Fermi surface and pseudogap in highly doped Sr₂IrO₄

Y. Alexanian
A. de la Torre
F. Baumberger
ResearchOpen Access03 Oct 2025
npj Quantum Materials

Volume: 10, P: 1-7
A formal Fe^III/V redox couple in an intercalation electrode

An Fe^III/V redox mechanism in Li₄FeSbO₆ on delithiation without Fe^IV or oxygen formation with resistance to aging, high operating potential and low voltage hysteresis is demonstrated, with implications for Fe-based high-voltage applications.

Hari Ramachandran
Edward W. Mu
William C. Chueh
Research15 Oct 2025
Nature Materials

P: 1-9
Are cross-regulatory interactions between homoeotic genes functionally significant?

A. Gonzalez-Reyes
N. Urquia
G. Morata
Research01 Mar 1990
Nature

Volume: 344, P: 78-80
Immunization Against Schistosoma japonicum in Rhesus Monkeys

H. F. HSÜ
S. Y. Li HSÜ
J. W. OSBORNE
Research26 Jun 1965
Nature

Volume: 206, P: 1338-1340
Mechanically activated snai1b coordinates the initiation of myocardial delamination for trabeculation

Myocardial contractile force and intracardiac hemodynamic shear stress coordinate the initiation of trabeculation in heart development. Here, the authors report that radially aligned myocardial strain activates snai1b⁺/Notch⁻ cardiomyocytes, initiating delamination for trabeculation.

Jing Wang
Aaron L. Brown
Tzung K. Hsiai
ResearchOpen Access24 Sept 2025
Nature Communications

Volume: 16, P: 1-16
Rapid polymer transport in concentrated solutions through the formation of ordered structures

B. N. Preston
T. C. Laurent
G. J. Checkley
Research09 Oct 1980
Nature

Volume: 287, P: 499-503
Dissecting regulatory non-coding GWAS loci reveals fibroblast causal genes with pathophysiological relevance to heart failure

Heart failure can be caused by cardiac fibroblasts replacing myocytes. Here, the authors use functional genomic data from fibroblasts, genetic signals enriched in people with heart disease, and gene perturbation analyses to link disease-associated regulatory elements to protein-coding genes.

Richard Gill
Daniel R. Lu
Yi-Hsiang Hsu
ResearchOpen Access10 Oct 2025
Nature Communications

Volume: 16, P: 1-17
Structural evidence for gene duplication in the evolution of the acid proteases

J. Tang
M. N. G. James
T. L. Blundell
Research16 Feb 1978
Nature

Volume: 271, P: 618-621
Uncovering hidden protein modifications with native top-down mass spectrometry

precisION discovers, localizes and quantifies protein modifications within complex proteoform assemblies through data-driven analysis of native top-down mass spectra.

Jack L. Bennett
Tarick J. El-Baba
Carol V. Robinson
ResearchOpen Access29 Sept 2025
Nature Methods

Volume: 22, P: 2127-2137
Biological Activities of Some α-Dithiosemicarbazones

P. A. BARRETT
ELIZABETH BEVERIDGE
J. K. H. WILDE
Research26 Jun 1965
Nature

Volume: 206, P: 1340-1341
Fission-track dating of pumice from the KBS Tuff, East Rudolf, Kenya

Anthony J. Hurford
A. J. W. Gleadow
C. W. Naeser
Research28 Oct 1976
Nature

Volume: 263, P: 738-740
History of the Mediterranean salinity crisis

Kenneth J. Hsü
Lucien Montadert
Ramil Wright
Research02 Jun 1977
Nature

Volume: 267, P: 399-403
Oral dosing of the nucleoside analog obeldesivir is efficacious against RSV infection in African green monkeys

In this work, authors show that the nucleoside prodrug obeldesivir has potent antiviral activity across respiratory syncytial virus (RSV) clinical isolates with a high resistance barrier. Once-daily obeldesivir treatment was efficacious against RSV in a non-human primate model.

Jared Pitts
J. Lizbeth Reyes Zamora
John P. Bilello
ResearchOpen Access11 Jul 2025
Nature Communications

Volume: 16, P: 1-12
Elliptic anisotropy measurement of the f₀(980) hadron in proton-lead collisions and evidence for its quark-antiquark composition

The quark structure of the f₀(980) hadron is still unknown after 50 years of its discovery. Here, the CMS Collaboration reports a measurement of the elliptic flow of the f₀(980) state in proton-lead collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV, providing strong evidence that the state is an ordinary meson.

A. Hayrapetyan
A. Tumasyan
A. Zhokin
ResearchOpen Access27 Aug 2025
Nature Communications

Volume: 16, P: 1-19
Subsecond optically controlled domain switching in freestanding ferroelectric BaTiO₃ membrane

Using experimental and atomistic simulations, the authors show that optical excitation lowers the energy barrier for domain wall motion. Combined with the imprint field, this effect enables subsecond optical control of domain switching in ferroelectric membranes.

Subhajit Pal
Lan-Tien Hsu
Joe Briscoe
ResearchOpen Access26 Aug 2025
Nature Communications

Volume: 16, P: 1-11
Structure and Distribution of Glycosyl Diglycerides in Bacteria

N. SHAW
J. BADDILEY
Research01 Jan 1968
Nature

Volume: 217, P: 142-144
Barcoded viral tracing identifies immunosuppressive astrocyte–glioma interactions

Using viral barcode tracing to detect interactions between glioblastoma cells and non-malignant astrocytes in patient samples, investigators discovered a pathway that reduces tumour-specific immunity and identified potential therapeutic targets.

Brian M. Andersen
Camilo Faust Akl
Francisco J. Quintana
Research25 Jun 2025
Nature

Volume: 644, P: 1097-1106
Peroxisomal metabolism of branched fatty acids regulates energy homeostasis

A UCP1-independent mechanism of thermogenesis involving ATP-consuming metabolism of monomethyl branched-chain fatty acids in peroxisomes is described and a previously unrecognized role for peroxisomes in adipose tissue thermogenesis is identified.

Xuejing Liu
Anyuan He
Irfan J. Lodhi
ResearchOpen Access17 Sept 2025
Nature

P: 1-9
Clinical impact of pharmacogenetic risk variants in a large chinese cohort

Here the authors reveal a study of 486,956 Han Chinese individuals showing that most people with genetic variants affecting drug response do not have the predicted adverse events, highlighting the challenges of implementing pharmacogenetics in clinical practice.

Chun-Yu Wei
Ming-Shien Wen
Pui-Yan Kwok
ResearchOpen Access09 Jul 2025
Nature Communications

Volume: 16, P: 1-15
Structure and assembly of filamentous bacterial viruses

D. A. Marvin
E. J. Wachtel
Research03 Jan 1975
Nature

Volume: 253, P: 19-23
FMRP Regulates the Nuclear Export of Adam9 and Psen1 mRNAs: Secondary Analysis of an N⁶-Methyladenosine Dataset

Cara J. Westmark
Bryan Maloney
Debomoy K. Lahiri
ResearchOpen Access01 Jul 2020
Scientific Reports

Volume: 10, P: 1-11
Tumour-specific STING agonist synthesis via a two-component prodrug system

STING is a promising drug target, but selective activation is necessary for safety and efficacy. Researchers have developed a two-component prodrug system for potent pharmacological activation of STING that offers excellent tumour targeting.

Nai-Shu Hsu
Cong Tang
Gonçalo J. L. Bernardes
ResearchOpen Access16 Sept 2025
Nature Chemistry

P: 1-11
Spousal correlations for nine psychiatric disorders are consistent across cultures and persistent over generations

A study of millions of couples shows spouses often share psychiatric disorders. This pattern is consistent across cultures (Taiwan and Nordic countries) and has persisted for generations, impacting how these disorders are inherited.

Chun Chieh Fan
Saeid Rasekhi Dehkordi
Shi-Heng Wang
Research28 Aug 2025
Nature Human Behaviour

P: 1-9
Myxomatosis and the Rabbit Flea

PAUL J. CHAPPLE
N. D. LEWIS
Research24 Jul 1965
Nature

Volume: 207, P: 388-389
Dynamic observation of defect annealing in CdTe at lattice resolution

R. Sinclair
F. A. Ponce
C. J. D. Catto
Research08 Jul 1982
Nature

Volume: 298, P: 127-131
Late Miocene Desiccation of the Mediterranean

K. J. HSÜ
W. B. F. RYAN
M. B. CITA
Research23 Mar 1973
Nature

Volume: 242, P: 240-244
Impact mechanics of the Cretaceous–Tertiary extinction bolide

John D. O'Keefe
Thomas J. Ahrens
Research08 Jul 1982
Nature

Volume: 298, P: 123-127
Recombination intermediates

J. R. S. FINCHAM
Research01 Jan 1981
Nature

Volume: 289, P: 97
Recombination intermediates (reply)

DEBRA J. WOLGEMUTH
MING-TA Hsu
Research01 Jan 1981
Nature

Volume: 289, P: 97
Removal of promoter CpG methylation by epigenome editing reverses HBG silencing

DNA methylation is a critical component for repression of fetal haemoglobin in adult blood cells. Removing DNA methylation from the fetal haemoglobin promoter effectively upregulates the gene, opening avenues for the treatment of blood disorders.

Henry W. Bell
Ruopeng Feng
Merlin Crossley
ResearchOpen Access27 Jul 2025
Nature Communications

Volume: 16, P: 1-16
Sequence of the lacI gene

Philip J. Farabaugh
Research24 Aug 1978
Nature

Volume: 274, P: 765-767
Inhibition of RNA cleavage but not polyadenylation by a point mutation in mRNA 3′ consensus sequence AAUAAA

Craig Montell
Eric F. Fisher
Arnold J. Berk
Research13 Oct 1983
Nature

Volume: 305, P: 600-605
Immunological Inertia in Pregnancy

J. M. ANDERSON
Research22 May 1965
Nature

Volume: 206, P: 786-787
mAChR4 suppresses liver disease via GAP-induced antimicrobial immunity

Chronic alcohol use in humans and mice downregulates small intestinal mAChR4 and reduces goblet-cell-associated antigen passage formation, disrupting antimicrobial immunity.

Cristina Llorente
Fernanda Raya Tonetti
Bernd Schnabl
Research20 Aug 2025
Nature

Volume: 646, P: 180-189
Palaeotectonic implications of increased late Eocene—early Oligocene volcanism from South Pacific DSDP sites

J. P. Kennett
C. von der Borch
M. G. Murphy
Research01 Aug 1985
Nature

Volume: 316, P: 507-511
Human metabolic adaptations and prolonged expensive neurodevelopment: A review

John Skoyles
ResearchOpen Access31 Oct 2008
Nature Precedings

P: 1
Human metabolic adaptations and prolonged expensive neurodevelopment: A review

John Skoyles
ResearchOpen Access05 May 2008
Nature Precedings

P: 1
Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form

Stephen Zewinger
Jochen Reiser
Thimoteus Speer
Research13 Feb 2023
Nature Immunology

Volume: 24, P: 412-413
Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs

A cloud-based machine-learning software that scores individual guide–target pairs and provides an overall summary score for a given guide that outperforms competing algorithms for the prediction of CRISPR–Cas9 off-target effects.

Jennifer Listgarten
Michael Weinstein
Nicolo Fusi
Research10 Jan 2018
Nature Biomedical Engineering

Volume: 2, P: 38-47
The Pathogenesis of Lead Encephalopathy in the Rat Pup: Effects of Maternal PbCO₃ Feedings from Birth

D Holtzman
J Shen Hsu
P Mortell
Research01 Nov 1978
Pediatric Research

Volume: 12, P: 1077-1082
The E. coli gene encoding heat stable toxin is a bacterial transposon flanked by inverted repeats of IS1

Magdalene So
Fred Heffron
Brian J. McCarthy
Research08 Feb 1979
Nature

Volume: 277, P: 453-456
Common ancestry for birds and crocodiles?

C. McGOWAN
A. J. BAKER
Research01 Jan 1981
Nature

Volume: 289, P: 97-98
Origin of the Alps and Western Mediterranean

K. J. HSÜ
Research03 Sept 1971
Nature

Volume: 233, P: 44-48
Vitamin B₁₂ and Protein Biosynthesis: Vitamin B₁₂ and Biosynthesis in Rat Liver

H. R. V. ARNSTEIN
J. L. SIMKIN
Research21 Feb 1959
Nature

Volume: 183, P: 523-525
Observations of solar oscillations of low and intermediate degree

T. L. Duvall Jr
J. W. Harvey
Research03 Mar 1983
Nature

Volume: 302, P: 24-27
Combined single-cell profiling of chromatin–transcriptome and splicing across brain cell types, regions and disease state

Joint profiling of chromatin and splicing in the brain uncovers shared and distinct patterns.

Wen Hu
Careen Foord
Hagen U. Tilgner
ResearchOpen Access22 Jul 2025
Nature Biotechnology

P: 1-13
Human neuromaturation, juvenile extreme energy liability, and adult cognition/cooperation

John Skoyles
ResearchOpen Access02 Apr 2012
Nature Precedings

P: 1

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