Nature Search

Natural variation of CTB5 confers cold adaptation in plateau japonica rice

Mechanisms confer to the enhanced cold tolerance in japonica rice have not been fully elucidated. Here, the authors report a homeodomain-leucine zipper (HD-Zip) I transcription factor encode gene CTB5 is responsible for japonica rice cold tolerance by interacting with genes in gibberellin and abscisic acid pathways.

Haifeng Guo
Shilei Gao
Jinjie Li
ResearchOpen Access25 Jan 2025
Nature Communications

Volume: 16, P: 1-18
Multidimensional predictors of fatigue in amyotrophic lateral sclerosis: a cross-sectional study in China

Fangfang Cai
Dandan Xu
Jing Zhou
ResearchOpen Access01 Jan 2026
Scientific Reports

Volume: 16, P: 1-8
Cortical hierarchy underlying homeostatic sleep pressure alleviation

Here, the authors find that the brain recovers during sleep in a hierarchical pattern: higher association areas quiet down while primary sensory regions ramp up during early sleep, with these differences diminishing as slow waves decline.

Qihong Zou
Guangyuan Zou
Jia-Hong Gao
ResearchOpen Access14 Nov 2025
Nature Communications

Volume: 16, P: 1-20
LAP2α drives breast tumorigenesis by mitigating replication stress

Yanhui Ma
Yan Qin
Kaiwen Bao
ResearchOpen Access03 Feb 2026
Cell Death & Disease

Volume: 17, P: 1-14
The multi-parameter optimized belief rule base for predicting student performance with interpretability

Jiaxing Li
Wenkai Zhou
Yuhe Wang
ResearchOpen Access19 Jan 2026
Scientific Reports

Volume: 16, P: 1-23
Helicobacter hepaticus promotes hepatic steatosis through CdtB-induced mitochondrial stress and lipid metabolism reprogramming

Here, the authors show that hepatic lipid accumulation induced by Helicobacter hepaticus involves mitochondrial dysfunction and disrupted lipid metabolism via CdtB-ROS-mTORC1-SREBP1 and NONO, highlighting CdtB as a key mediator and potential therapeutic target.

Shanhao Jin
Liqi Zhu
Quan Zhang
ResearchOpen Access26 Aug 2025
Nature Communications

Volume: 16, P: 1-17
Spin Seebeck in the weakly exchange-coupled Van der Waals antiferromagnet across the spin-flip transition

The authors find the magnon spin transport in CrSP₄/Pt (Ta) can be effectively modulated through adjustments in temperature and applied magnetic field, particularly at the spin-flip field.

Xue He
Shilei Ding
Rui Wu
ResearchOpen Access28 Mar 2025
Nature Communications

Volume: 16, P: 1-8
Structural basis of RNA polymerase complexes in African swine fever virus

The African swine fever virus represents a threat to global pig production. Here, the authors determine the cryo-EM structures of ASFV RNA polymerase, and suggest that the M1249L subunit may modulate polymerase activity in cells.

Guoliang Zhu
Fei Xi
Haixue Zheng
ResearchOpen Access08 Jan 2025
Nature Communications

Volume: 16, P: 1-13
Trim47 prevents hematopoietic stem cell exhaustion during stress by regulating MAVS-mediated innate immune pathway

During periods of stress, it is required to maintain the haematopoietic stem cell (HSC) pool. Here the authors show that Trim47 is important in the survival and function of HSCs after exposure to stress, and prevents haematopoietic failure by inhibiting MAVS-mediated excessive activation of the innate immune pathway.

Fang Chen
Yukai Lu
Junping Wang
ResearchOpen Access08 Aug 2024
Nature Communications

Volume: 15, P: 1-15
DNA replication fork speed acts as a pacer in cortical neurogenesis

DNA fork speed is considered as a potential regulator of stem cell fate. Here, the authors explore its role in radial glial cells (RGCs) during brain development and impacts on behaviour. Notably, an increase in fork speed induces RGCs detach from ventricular zone, mimicking outer-RGC like cells.

Jianhong Wang
Yifan Kong
Lei Shi
ResearchOpen Access18 Nov 2025
Nature Communications

Volume: 16, P: 1-20
Directed synthesis of N1/N3-histidine modified by 2-hydroxyethylthioethyl and identification in sulfur mustard-exposed plasma

Sulfur mustard (HD) is a highly reactive chemical warfare agent capable of alkylating proteins, however, the absolute quantification of HD-exposed biomarkers remains challenging. Here, the authors prepare N1/N3-histidine modified with 2-hydroxyethylthioethyl using precision synthesis strategies and employ them as external standards to identify the HD-exposed plasma.

Long Wen
Zhibin Shu
Shilei Liu
ResearchOpen Access08 Mar 2025
Communications Chemistry

Volume: 8, P: 1-9
AI-based large-scale screening of gastric cancer from noncontrast CT imaging

Artificial intelligence-based detection of gastric cancer at different stages from noncontrast computed tomography is suggested to be feasible in a retrospective analysis of large and diverse cohorts, including real-world populations in opportunistic and targeted screening scenarios.

Can Hu
Yingda Xia
Xiangdong Cheng
ResearchOpen Access24 Jun 2025
Nature Medicine

Volume: 31, P: 3011-3019
Prime editor with rational design and AI-driven optimization for reverse editing window and enhanced fidelity

Expanding editing scope while reducing byproducts is now possible for prime editing. Here, authors develop reverse prime editing (rPE), a SpCas9-based tool enabling editing in reverse window with high fidelity and demonstrate its use in inserting therapeutic variants.

Chao Yang
Qingxiao Fang
Jihui Hao
ResearchOpen Access03 Jun 2025
Nature Communications

Volume: 16, P: 1-14
Achieving tissue-level softness on stretchable electronics through a generalizable soft interlayer design

Stretchable electronics are attractive for a range of biomedical applications, but are challenging to prepare with suitable mechanical properties. Here, the authors report the use of a soft interlayer that allows the development of stretchable electronics with tissue-like material properties.

Yang Li
Nan Li
Sihong Wang
ResearchOpen Access26 Jul 2023
Nature Communications

Volume: 14, P: 1-10
Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry

Human proteins SERINC3 and SERINC5 are HIV-1 restriction factors that reduce viral infectivity. Here, the authors show that SERINC3 has architecture resembling non-ATP dependent lipid transporters and induces loss of membrane asymmetry correlated with changes in envelope conformation and loss of infectivity.

Susan A. Leonhardt
Michael D. Purdy
Mark Yeager
ResearchOpen Access20 Jul 2023
Nature Communications

Volume: 14, P: 1-16
A weakly solvating electrolyte towards practical rechargeable aqueous zinc-ion batteries

The practical deployment of aqueous zinc-ion batteries is hindered by the structure deterioration and side reactions at electrodes. Here, the authors introduce a weakly solvating electrolyte with butanone as an electrolyte additive to stabilize both the cathode and anode of aqueous zinc-ion batteries simultaneously.

Xin Shi
Jinhao Xie
Xihong Lu
ResearchOpen Access05 Jan 2024
Nature Communications

Volume: 15, P: 1-9
ABCD2 score has equivalent stroke risk prediction for anterior circulation TIA and posterior circulation TIA

Shuang Cao
Lu Zhao
Yuming Xu
ResearchOpen Access26 Aug 2023
Scientific Reports

Volume: 13, P: 1-7
Author Correction: A weakly solvating electrolyte towards practical rechargeable aqueous zinc-ion batteries

Xin Shi
Jinhao Xie
Xihong Lu
Amendments and CorrectionsOpen Access15 Nov 2024
Nature Communications

Volume: 15, P: 1-4
Stability and its mechanism in Ag/CoO_x/Ag interface-type resistive switching device

Jianbo Fu
Muxin Hua
Jinbo Yang
ResearchOpen Access19 Oct 2016
Scientific Reports

Volume: 6, P: 1-8
An allosteric ligand-binding site in the extracellular cap of K2P channels

TREKs are members of the two-pore domain potassium (K2P) channels, being important clinical targets. Here the authors identify inhibitors of K2P that bind to an allosteric site located in their extracellular cap, suggesting that it might be a promising drug target for these channels.

Qichao Luo
Liping Chen
Huaiyu Yang
ResearchOpen Access29 Aug 2017
Nature Communications

Volume: 8, P: 1-9
Electrospray deposition device used to precisely control the matrix crystal to improve the performance of MALDI MSI

Shilei Li
Yangyang Zhang
Zhenwen Zhao
ResearchOpen Access25 Nov 2016
Scientific Reports

Volume: 6, P: 1-10
An excellent navigation system and experience in craniomaxillofacial navigation surgery: a double-center study

Jiewen Dai
Jinyang Wu
Shilei Zhang
ResearchOpen Access16 Jun 2016
Scientific Reports

Volume: 6, P: 1-7
ACSS1 co-opts acetyl-CoA metabolism to drive DNA repair and undermine radiotherapy efficacy in breast cancer

Xiao Fu
Yingyu Zhu
Jie Yang
ResearchOpen Access18 Dec 2025
Cell Death & Disease

Volume: 17, P: 1-15
Analysis of factors influencing sleep disorders in patients with amyotrophic lateral sclerosis

Qianping Jiang
Dan Yang
Jing Zhou
ResearchOpen Access30 Sept 2025
Scientific Reports

Volume: 15, P: 1-9
USP9X regulates centrosome duplication and promotes breast carcinogenesis

USP9X is a deubiquitinating enzyme with many known substrates and functions; it has been linked to cancer but the mechanisms remain unclear. Here Liet al. report that USP9X stabilizes the centrosomal protein CEP131 leading to centrosome amplification and breast cancer development.

Xin Li
Nan Song
Lei Shi
ResearchOpen Access31 Mar 2017
Nature Communications

Volume: 8, P: 1-16
USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization

Histone chaperone ASF1A is often dysregulated in cancers, however the regulation of its abundance is unclear. Here, the authors show that USP52 promotes ASF1A stability through deubiquitination while impairment of this stability reduces breast tumorigenesis and confers sensitivity to DNA damage.

Shangda Yang
Ling Liu
Lei Shi
ResearchOpen Access29 Mar 2018
Nature Communications

Volume: 9, P: 1-17
Development and validation of a basement membrane inflammatory response gene signature in lung adenocarcinoma

Shilei Liu
Fengchu Liao
Pengfei Zhang
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-18
The profitability implications of supplier concentration during economic recession and restoration: the moderating role of supply localization

Jing Liang
Shilei Yang
ResearchOpen Access27 Sept 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-13
Association between anxiety disorder, anxiolytic drugs, and risk of incident Parkinson’s disease

Xiaoyan Hao
Zhiyun Wang
Changhe Shi
ResearchOpen Access21 Aug 2025
npj Parkinson's Disease

Volume: 11, P: 1-10
Experimental study on biological solutions for anchoring earthen heritage sites

Jianwei Zhang
Tiansai Zhang
Yuanmin Zhang
ResearchOpen Access18 Jul 2025
npj Heritage Science

Volume: 13, P: 1-11
Unprecedented non-hysteretic superelasticity of [001]-oriented NiCoFeGa single crystals

NiCoFeGa single crystals exhibit large non-hysteretic superelasticity over broad temperature and composition ranges. It is attributed to the continuous phase transition with applied stress, which is related to the fluctuation of entangled ordered and disordered crystal structures.

Haiyang Chen
Yan-Dong Wang
Yang Ren
Research16 Mar 2020
Nature Materials

Volume: 19, P: 712-718
Transcription factor Nkx2-3 maintains the self-renewal of hematopoietic stem cells by regulating mitophagy

Mengjia Hu
Naicheng Chen
Junping Wang
Research24 Apr 2023
Leukemia

Volume: 37, P: 1361-1374
Tespa1 facilitates hematopoietic and leukemic stem cell maintenance by restricting c-Myc degradation

Yukai Lu
Lijing Yang
Junping Wang
ResearchOpen Access30 Mar 2023
Leukemia

Volume: 37, P: 1039-1047
The improvement of photocatalysis O₂ production over BiVO₄ with amorphous FeOOH shell modification

Ying Zhang
Lei Shi
Zhanxu Yang
ResearchOpen Access13 Dec 2019
Scientific Reports

Volume: 9, P: 1-10
CD63 acts as a functional marker in maintaining hematopoietic stem cell quiescence through supporting TGFβ signaling in mice

Mengjia Hu
Yukai Lu
Junping Wang
Research06 Aug 2021
Cell Death & Differentiation

Volume: 29, P: 178-191
CDK19 regulates the proliferation of hematopoietic stem cells and acute myeloid leukemia cells by suppressing p53-mediated transcription of p21

Zihao Zhang
Yukai Lu
Junping Wang
Research02 Feb 2022
Leukemia

Volume: 36, P: 956-969
MACC1 ablation suppresses the dedifferentiation process of non-CSCs in lung cancer through stabilizing KLF4

Zhuoshi Li
Shiqing Wang
Chundong Gu
ResearchOpen Access18 Dec 2024
Cell Death Discovery

Volume: 10, P: 1-14
Manufacturer’s agency channel encroachment on an online retail platform

Man Guo
Shilei Yang
Yanglei Li
ResearchOpen Access23 Nov 2024
Scientific Reports

Volume: 14, P: 1-16
CRLF1 bridges AKT and mTORC2 through SIN1 to inhibit pyroptosis and enhance chemo-resistance in ovarian cancer

Cong Xiang
Li Chen
Xiongwei Cai
ResearchOpen Access10 Sept 2024
Cell Death & Disease

Volume: 15, P: 1-16
Reduction Impairs the Antibacterial Activity but Benefits the LPS Neutralization Ability of Human Enteric Defensin 5

Cheng Wang
Mingqiang Shen
Junping Wang
ResearchOpen Access10 Mar 2016
Scientific Reports

Volume: 6, P: 1-12
CDC42 governs normal oviduct multiciliogenesis through activating AKT to ensure timely embryo transport

Ruiwei Jiang
Xiaofang Tang
Shuangbo Kong
ResearchOpen Access02 Sept 2022
Cell Death & Disease

Volume: 13, P: 1-15
Bioinspired organic optoelectronic synaptic transistors based on cellulose nanopaper and natural chlorophyll-a for neuromorphic systems

Junyao Zhang
Dapeng Liu
Jia Huang
ResearchOpen Access24 May 2022
npj Flexible Electronics

Volume: 6, P: 1-10
LAP2α orchestrates alternative lengthening of telomeres suppression through telomeric heterochromatin regulation with HDAC1: unveiling a potential therapeutic target

Bing Wang
Haomeng Kou
Feng Wang
ResearchOpen Access19 Oct 2024
Cell Death & Disease

Volume: 15, P: 1-15
Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in glioblastoma cell lines

Yulin Zhang
Yang Kong
Xingang Li
ResearchOpen Access08 Jan 2021
Oncogene

Volume: 40, P: 1425-1439
The dual role of glioma exosomal microRNAs: glioma eliminates tumor suppressor miR-1298-5p via exosomes to promote immunosuppressive effects of MDSCs

Yanhua Qi
Chuandi Jin
Gang Li
ResearchOpen Access02 May 2022
Cell Death & Disease

Volume: 13, P: 1-15
Vesicular stomatitis virus G protein transmembrane region is crucial for the hemi-fusion to full fusion transition

Yali Ci
Yang Yang
Lei Shi
ResearchOpen Access13 Jul 2018
Scientific Reports

Volume: 8, P: 1-11
Excess soluble alkalis to prepare highly efficient MgO with relative low surface oxygen content applied in DMC synthesis

Ju Liu
Fei Chen
Lei Shi
ResearchOpen Access22 Oct 2021
Scientific Reports

Volume: 11, P: 1-17
Autism-like social deficit generated by Dock4 deficiency is rescued by restoration of Rac1 activity and NMDA receptor function

Daji Guo
Yinghui Peng
Lei Shi
ResearchOpen Access06 Aug 2019
Molecular Psychiatry

Volume: 26, P: 1505-1519
ROS inhibit autophagy by downregulating ULK1 mediated by the phosphorylation of p53 in selenite-treated NB4 cells

Y Ci
K Shi
C Xu
ResearchOpen Access27 Nov 2014
Cell Death & Disease

Volume: 5, P: e1542
GATA3 cooperates with PARP1 to regulate CCND1 transcription through modulating histone H1 incorporation

L Shan
X Li
L Shi
Research15 Jul 2013
Oncogene

Volume: 33, P: 3205-3216

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