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Self-intercalated Chromium tellurides consist of CrTe₂ van der Waals layers, with additional Chromium atoms residing in the van der Waals gap. This highly tuneable class of magnetic materials has presented a range of unique magnetic phenomena, and here Bigi, Jego, Polewczyk et al add to this by showing that CrTe₂ (δ = 0.25 − 0.50) hosts orthogonal ferromagnetism.

Internucleosomal linker length alters the stability and dynamics of chromatin condensates by shifting the balance between inter- and intramolecular interactions. Further, by changing the linker lengths, a remodeler can induce or suppress chromatin phase separation.

NIPBL perturbation activates long terminal repeat (LTR)-derived alternative promoters due to reorganization of chromatin’s hierarchical structure, leading to LTR co-option and oncogene activation in melanoma cell lines.

Exploratory post hoc analysis of molecular residual disease from the ADAURA trial of adjuvant osimertinib in patients with resected EGFR-mutated stage IB–IIIA non-small-cell lung cancer shows that molecular residual disease detection predicts disease recurrence with long-term adjuvant osimertinib treatment.

Anodic pulsing during electrocatalytic CO₂ reduction has been shown to enhance activity and selectivity towards hydrocarbons and alcohols on copper yet the nature of the active sites remains unclear. Here, correlated spectro-microscopy in a quasi in situ experimental set-up provides information on the formation of specific facets and oxidation states under reactive conditions.

Optical frequency combs are key tools in spectroscopy and telecom. Here, authors report a stable and broadband comb (>10 THz) from a high-Q fiber Fabry-Perot resonator via Kerr-Brillouin passive mode-locking. This easily integrable platform ensures state-of-the-art photonic performance.

Holographic techniques allow for the construction of 3D images by controlling the wave front of light beams. Huang et al.develop ultrathin plasmonic metasurfaces to provide 3D optical holographic image reconstruction in the visible and near-infrared regions for circularly polarized light.

Peer review information: Nature Communications thanks Shiqing Deng, and the other, anonymous, reviewer(s) for their contribution to the peer review of this work. A peer review file is available.

Hydrogen atoms in water ices, under pressures at which they might exist in ocean exoplanets and icy moons, exhibit dynamics that are still poorly understood. Here, ¹H-NMR experiments approaching the Mbar range shed light on the symmetrisation of hydrogen bonds preceding and accompanying the transformation of ice VII into ice X.

Five-year follow-up and prespecified exploratory biomarker analysis from the phase 3 KEYNOTE-426 trial show that pembrolizumab plus axitinib compared to sunitinib as first-line therapy continues to show overall and progression-free survival benefits in patients with advanced clear cell renal cell carcinoma and indicate that a T-cell-inflamed gene expression profile is predictive of response.

This study shows that aboveground plant diversity is only weakly related to belowground mycorrhizal fungal diversity, although these relationships can be stronger at regional scales. Therefore, conservation efforts centered only on plant diversity may overlook critical fungal diversity hotspots.

Tomonaga-Luttinger liquid behavior has been observed within 1D defects in transition metal dichalcogenides. Here, using complementary experiments and engineered defects, the authors demonstrate the importance of graphene as a substrate and its role in the formation of this quasiparticle excitation in 2D WS₂.

Surface structures can have an important effect on the traits of two-dimensional electron liquids. Here, the authors demonstrate how the surface terminations of SrTiO₃(001) affect the mechanism and properties of the two-dimensional electron liquid.

Understanding liquid behavior is a challenge due to their disorder nature and rapid molecular rearrangements. Here, the authors show how weak interactions between OH groups and aromatic rings can participate in cooperative mechanisms that give rise to highly structured molecular arrangements in the liquid state.

Ocean stratification — density-related layering of seawater — influences oceanographic and climatic processes. This Review outlines observed and projected changes in stratification, noting a 0.8% dec⁻¹ increase in 0–2,000 m stratification from 1960–2024, and a further 1.4% dec⁻¹ increase by 2100 under SSP2-4.5.

A gold catalyst supported on intergrown titanosilicate zeolites enhances propene oxide production by activating oxygen-transfer intermediates more efficiently at Ti interface sites.

Parvalbumin-positive interneurons in the hippocampal CA3 substantially reduce firing on approach to and at goal locations while food-deprived mice learn to find food.

The icy surface compositions, as revealed by JWST, of small bodies beyond the orbit of Neptune can be classified into three groups that can be related to the ice retention lines in the early Solar System, possibly before the planets migrated.

The authors present nuclear magnetic resonance data on lanthanum superhydrides (LaHx) under high pressure. They find that the hydrogen is in a highly diffusive state which results in a dynamic de-hydrogenation of the sample on a time scale of weeks.

A phase 1 feasibility trial shows that bilateral deep brain stimulation within the central lateral thalamus can be safely applied and is associated with improved executive control.

Structural analyses of antibody-virus complexes offer critical insights into immune recognition mechanisms. In this report, we present how a patient-derived IgG recognizes a quaternary epitope on EEEV particles through strictly bivalent interactions.

Electric fields in the solar atmosphere are not studied as widely as the magnetic fields mainly due to small, short living signals. Here, the authors show measurement of an electric field associated with magnetic diffusion triggering an energetic event in the solar atmosphere.

As presented at the 2025 ASCO Annual Meeting: in a randomized controlled phase 3 trial evaluating subcutaneous administration of sasanlimab, an anti-PD-1 inhibitor, with Bacillus Calmette–Guérin induction and maintenance treatment, combination treatment significantly improved event-free survival versus standard-of-care therapy.

Van der Waals heterostructures can be combined with metallic nanostructures to enable enhanced light–matter interaction. Here, the authors fabricate a broadband mechanical electro-optical modulator using a graphene/hexagonal boron nitride vertical heterojunction, suspended over a gold nanostripe array.

This study presents a nuclear magnetic resonance-based method to determine local structure and bonding of Pt single-atom catalysts.

Semipermeable polymeric anion exchange membranes are essential for separation, filtration and energy conversion technologies such as fuel cells. Quasi-elastic neutron scattering is now used to disentangle water, polymer relaxation and OH⁻ diffusional dynamics in a commercially available membrane.

Here they show that myogenic cells shift their bioactive lipid profile from pro-inflammatory to pro-resolving during myogenesis. Disrupting this transition impairs differentiation, whereas Protectin-D1 restores fusion and improves muscle phenotype in a dystrophic model.

Tanner’s law describes the spreading dynamics of droplets made of Newtonian viscous fluids. Here, the authors demonstrate that this law remains valid for phase-separated binary liquids close to their critical point, and thus for all the associated universality class.

The emergence of universal collective behaviour is demonstrated through collisions of electron droplets containing up to five particles, which exhibit strong all-body correlations characteristic of a Coulomb liquid.

Structural vacancies in crystalline solids have potential in tuning optoelectronic properties. However, the random distribution of vacancies a problem when creating materials with completely reproducible functions. Here authors use vacancy engineering to improve electronic communication between cluster units in 3D orientationally ordered MOF crystals.

The authors use nitrogen-vacancy centre magnetometry to explore layer number and magnetic field evolution of ferromagnetic and antiferromagnetic domains in the A-type antiferromagnet CrPS₄.

This study demonstrates a sustainable photocatalytic route for the production of ethylene glycol and H₂ using methyl tert-butyl ether as the substrate, offering a greener alternative to energy-intensive, petroleum-based industrial processes.

The composition and potential roles of extracellular vesicles released by gut archaea are poorly understood. Here, Weinberger et al. show that extracellular vesicles produced by human gut-derived methanogenic archaea are enriched in adhesin-like proteins, can be taken up by macrophages, and elicit responses in immune and epithelial cells.

Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease group with CAR T cells offering therapeutic success in otherwise hard-to-treat cases. Here, authors study the in vivo expansion and persistence of CAR T cells in the peripheral blood of successfully treated DLBCL patients, demonstrating that two different CD8+ precursor phenotypes in the initial cell product give rise to two independent waves of clonally expanded CAR T cells with distinct phenotypes in peripheral blood.

The rapid decay of Earth’s dipole magnetic field has recently captured the public imagination. Here, the authors present a southern hemisphere magnetic record from South African Iron Age sites using oriented samples in the floors and suggest that the anomalous field behaviour is not just a recent feature.

A 50 microRNA-based dynamic risk score for stratifying individuals with and without type 1 diabetes was developed using samples obtained from multicenter and multiethnic cohorts.

N-glycans on glycoRNAs prevent innate immune sensing of endogenous small RNAs, and the natural mechanism they use demonstrates how glycoRNAs exist on the cell surface and in the endosomal network without inducing autoinflammatory responses.

An inflammatory process may increase the risk of arrhythmias after transcatheter aortic valve replacement. Here, the authors show that periprocedural treatment with colchicine may reduce the incidence of new-onset arrhythmias and subclinical leaflet thrombosis after transcatheter aortic valve replacement.

The co-occurrence of marine heatwaves with extremes of high acidity and low chlorophyll concentrations has increased dramatically over the past two decades in the equatorial and South Atlantic. El Niño events seem to be the common driver of the different local mechanisms leading to these compound extreme events.

Cathodic corrosion of platinum is investigated using operando high-resolution X-ray absorption spectroscopy matched with density functional calculations. Platinum hydrides are found to be reaction intermediates in conditions at which these species are expected to be unstable.

Gene activity levels predict how often and how strongly genes turn on and off. Using live imaging in fruit fly embryos, the authors uncover a conserved rule linking transcriptional bursts to gene activity across time, space and species.

Lind et al. exposed rats to low doses of bisphenol A in utero. This induces a sex-specific blood metabolic profile in adult rats resembling that of humans with metabolic syndrome, with the bone marrow transcriptome exhibiting extensive changes.