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As an important class of open-shell molecules characterized by triangular nanographenic structures and interesting magnetic properties with high-spin ground states, triangulenes are attractive targets. Here, the authors report a highly stable aza-derivative of [4]triangulene triradical with a quartet ground state.

Astroblastoma (AB) is an uncommon brain tumour and its origin remains unknown. Here, the authors perform integrative molecular analysis of 35 AB-like tumours and provide evidence that these arise in the context of epigenetic and genetic changes in neural progenitors occurring during brain development.

Language models can write human-readable code that captures general design rules, generating whole families of quantum experiments at once. A design strategy described here makes results interpretable and scalable, as well as accelerates discovery.

The STAR experiment at the Relativistic Heavy Ion Collider at Brookhaven National Laboratory demonstrates evidence of spin correlations in \(\Lambda \bar{\Lambda }\) hyperon pairs inherited from virtual spin-correlated strange quark–antiquark pairs during QCD confinement.

Spin transport properties of magnetically ordered materials have been well studied. Here, the authors report an anomalous spin signal exhibiting spin transport over 480 microns in the frustrated hyperkagome magnetic insulator Gd₃Ga₅O₁₂.

Spatial transcriptomics (ST) technologies link tissue morphology with gene expression, but remain expensive to use; furthermore, models that predict ST data from histopathology images possess considerable limitations. Here, the authors develop STimage, a deep learning probabilistic framework for ST prediction from histopathology images while prioritising robustness and interpretability.

The authors study a topological insulator (TI) sandwiched between two magnetic TIs. By keeping one of the magnetic TIs insulating, while tuning the other one into a metallic regime, they find half quantized anomalous Hall conductance, a boundary signature consistent with a quantized axion field.

Examples of materials with non-trivial band topology in the presence of strong electron correlations are rare. Now it is shown that quantum fluctuations near a quantum phase transition can promote topological phases in a heavy-fermion compound.

The CMS Collaboration reports the measurement of the spin, parity, and charge conjugation properties of all-charm tetraquarks, exotic fleeting particles formed in proton–proton collisions at the Large Hadron Collider.

Identifying jets originating from heavy quarks plays a fundamental role in hadronic collider experiments. In this work, the ATLAS Collaboration describes and tests a transformer-based neural network architecture for jet flavour tagging based on low-level input and physics-inspired constraints.

The authors identify feeblin, an inhibitory compound of the proinflammatory TLR7/8/9-IRF5 pathway with therapeutic potential, which acts by binding SLC15A4 via an allosteric mechanism mediating degradation of its signaling partner TASL.

The authors report suspended Lamb-wave resonators using sub-100 nm ultrathin lithium niobate, achieving resonant frequencies of nearly 220 GHz-doubling prior records and holding exciting prospects for terahertz nanomechanics.

Standard approaches for identifying pleiotropic genetic variants may lead to spurious results. Here the authors present a new statistical method and show that it uncovers five genes linked to metabolites in METSIM participants, which were previously undetected by existing methods.

A new artificial intelligence model, DeepSeek-R1, is introduced, demonstrating that the reasoning abilities of large language models can be incentivized through pure reinforcement learning, removing the need for human-annotated demonstrations.

Fe-cyclopentadienone complexes have been widely utilized in various hydrogenation and dehydrogenation catalytic processes, yet their applications have largely been restricted to non-asymmetric versions. Herein, the authors report the synthesis of a chiral Fe- cyclopentadienone complex and its application in the catalytic asymmetric hydrogenation of acylsilanes.

This study shows that animals can adapt behaviorally to warm environments by speeding up their internal clocks. Suprathreshold temperatures activate the Lim1 pathway in the fly brain, resulting in accelerated circadian clock activity and increased early morning activity.

This study demonstrates that resting-state fMRI networks can rapidly reconfigure in response to a single, 10-ms thalamic neural population activity input, revealing how brain networks mediate fast neural information flow and processing.

Therapeutic gene editing in vivo is an ongoing challenge. Here, authors demonstrate Cas9 nickase guided DNA ligation as a nonviral method for installing permanent genomic corrections with favorable on target edit profiles in model animal cell types and adult mice.

In 2001 superconductivity with a high critical temperature of 39 K was discovered in MgB₂, but efforts since then to identify other diboride-family superconductors have been mostly unsuccessful. Here, the authors report the discovery of superconductivity in pressurized WB₂, originating from the formation of metastable stacking faults and twin boundaries that exhibit a local structure resembling MgB₂.

In returning Thouless pumping, the quantized charge is pumped during the first half of the cycle and returns to zero during the second. Here, authors demonstrate returning Thouless pumping experimentally with a symmetry-protected delicate topological insulator, made of a two-dimensional acoustic crystal.

The formation of organelles was a pivotal point in eukaryotic evolution. Here they show that Archaea possess Arf-like GTPases that can perform key organelle-producing mechanisms when expressed in a eukaryotic cell, laying the foundation for the evolution of endomembrane organelles.

Atomically dispersed catalysts show promising activity for electrochemical reactions but often suffer from limited stability. Here, the authors report an atom-ordering strategy that forms triangular Co sites to activate the substrate for durable alkaline hydrogen production.

Intercalating alkali metals into picene—a hydrocarbon with five linearly fused benzene rings—results in superconducting materials. Now, alkali-metal-doped phenanthrene, which consists of three fused benzene rings, is also found to be superconducting, opening up a broader class of organic superconductors.

JWST/NIRSpec observations of the 49 Ceti debris disk reveal spatially resolved, fluorescently excited CO emission, indicating a secondary origin of the gas in debris disks (that is, from the collision of volatile-rich bodies).

While Bell inequalities have been violated several times—mostly in photonic systems—their violations within particle physics experiments are less explored. Here, the BESIII Collaboration showcases Bell-violating nonlocal correlations between entangled hyperon pairs.

Maternal SETD2 deficiency leads to loss of H3K36me3, aberrant DNA methylation and ectopic H3K4me3 and H3K27me3 in mouse oocytes. Maternal depletion of SETD2 causes oocyte defects and subsequent zygotic arrest.

The authors report their observation of the fractional quantum anomalous Hall effect in rhombohedral hexalayer graphene/hBN moiré superlattice devices.

In ABA trilayer graphene, a temperature gradient generates a transverse voltage that scales quadratically with the gradient and reaches an effective Nernst coefficient of 300 µV K⁻¹ near the charge neutrality point.

The development of practical photonic quantum technologies will be aided by the spatial control of entangled photons. Lenget al. achieve on-chip spatial control of entangled photons by using domain engineering, rather than by using external optical elements.

The semileptonic decay channels of the Λc baryon can give important insights into weak interaction, but decay into a neutron, positron and electron neutrino has not been reported so far, due to difficulties in the final products’ identification. Here, the BESIII Collaboration reports its observation in e+e- collision data, exploiting machine-learning-based identification techniques.

Thermal lepton pairs are ideal probes for the temperature of quark-gluon plasma. Here, the STAR Collaboration uses thermal electron-positron pair production to measure quark-gluon plasma average temperature at different stages of the evolution.

Investigating the inner structure of baryons is important to further our understanding of the strong interaction. Here, the BESIII Collaboration extracts the absolute value of the ratio of the electric to magnetic form factors and its relative phase for e + e − → J/ψ → ΛΣ decays, enhancing the signal thanks to the vacuum polarisation effect at the J/ψ peak.

Solitons may develop when strain forms at line defects separating commensurate domains in misaligned or lattice-mismatched van der Waals heterostructures. Here, the authors use atomic-force microscopy and nano-infrared spectroscopy to image solitons in thin hBN crystals in the form of long-range periodic superstructures, creating sub-surface hexagonal networks with periods of a few hundred nanometers.

The synthesis of atom-thin amorphous films remains challenging as their thermodynamically favourable grains are neither two dimensional nor layered. Here a droplet-driven nanoribbon-to-film growth strategy is reported to achieve amorphous metal chalcogenides at the single-layer limit.

The quark structure of the f₀(980) hadron is still unknown after 50 years of its discovery. Here, the CMS Collaboration reports a measurement of the elliptic flow of the f₀(980) state in proton-lead collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV, providing strong evidence that the state is an ordinary meson.

Earth-abundant TiO₂ is a promising negative electrode material for low-cost sodium-ion batteries. Here, authors show that ordered rocksalt NaTiO₂ nanograins are in situ formed by electrochemically cycling with Na⁺ ions in anatase TiO₂, which determines the pseudocapacitive high-rate capability.

The interfaces between ferromagnets and superconductors receive many attentions due to emergent relativistic spin-orbit coupling. Here, the authors provide possible evidence for spin triplet Andreev reflection at the interface between a van der Waals ferromagnet Fe_0.29TaS₂ and a s-wave superconductor NbN.

Ginzburg–Landau theory provides a powerful framework for describing the behaviour of conventional superconductors without detailed microscopic information about them. Bao et al.construct a similar framework for describing spin superconductivity, a recently proposed analogue of conventional superconductivity.

Non-Hermiticity is usually considered detrimental to quasiparticle physics. Here, the authors show that such an assumption of Hermiticity can be lifted in the context of a lattice model containing two non-Hermitian Dirac cones, with one hosting amplifying Dirac quasiparticles and the other hosting decaying ones.

A millimetre-wave dual-rail resonator that is incorporated into a suspended lithium niobate resonator can provide efficient electromechanical transduction in the sub-terahertz regime.

Long-lasting oxygen catalysts are crucial for rechargeable zinc-air batteries. Here, the authors report that placing tungsten atoms next to iron atoms within N₄ units creates durable Fe-N₄/W-N₄ diatomic sites, enabling a zinc-air battery to cycle reliably for more than 10,000 h.

An approach that integrates electrochemical CO₂ reduction and biological denitrification provides a new solution for nitrogen removal, where the formate obtained from CO₂ is used directly as the carbon source in the denitrification process in wastewater treatment.

Silver nanoparticles are useful antimicrobial agents in water purification systems. Here the fabrication of silver nanoparticles that include a magnetic layer could lead to improved purification systems as it allows the recovery of the nanoparticles by magnetic fields.

The study of isotopes away from the beta stability valley is crucial for the understanding of nuclear structure, especially for neutron-deficient heavy nuclei. Here, the authors report the observation of the alpha-decay isotope 210-protactinium (Pa), extending the alpha-decay systematics of underexplored regions of the nuclides chart.

Fractional quantum Hall states in 2D electron gases arise due to strong electron-electron interactions, which makes a general theoretical understanding difficult. Fu et al. present data showing the ν = 5/3 quantum Hall state has a 3/2 plateau in the diagonal resistance that has not been captured by existing models.

Cancer patients suffer from dysgeusia. Here, the authors propose a gustatory interface for operative assessment and taste decoding, offering potential to improve the quality of life of individuals suffering from tongue cancer.

A key feature of Majorana zero modes (MZMs) is their non-Abelian fusion rule, characterized by multiple outcomes. Here, the authors introduce a minimal setup where coupling a tunable fermionic mode to a single MZM allows the control of fusion loops, yielding distinct charge pumping that serves as a direct experimental signature.