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Discovery of a nearly complete skeleton of Huayracursor jaguensis, a Carnian dinosaur from the Northern Precordillera Basin in northwestern Argentina provides evidence of increased body size and early cervical elongation during the Late Triassic epoch.

Loretan and colleagues present a low-cost smartphone-based microscope capable of detecting single-molecule fluorescence. This approach opens doors to personalised and widely distributed applications in diagnostics, biosensing, and science education.

Over 20 species of geographically and phylogenetically diverse bird species produce convergent whining vocalizations towards their respective brood parasites. Model presentation and playback experiments across multiple continents suggest that these learned calls provoke an innate response even among allopatric species.

Control of quantum interference in engineered atomic-scale systems could enable precise manipulation of quantum states, however it has remained challenging. Here the authors demonstrate electrically tunable quantum interference in a system of Ti atoms on MgO surface, using a scanning probe microscope setup.

A geological, petrographic and geochemical survey of distinctive mudstone and conglomerate outcrops of the Bright Angel formation on Mars reveals textures, chemical and mineral characteristics, and organic signatures that warrant consideration as potential biosignatures.

The Perseverance rover has made the most definitive identification of Fe-phosphate minerals on Mars to date. High-resolution chemical and textural PIXL analyses suggest they originally formed after vivianite in a potentially habitable environment.

Cell-type-specific electrophysiological recording, fibre photometry and optogenetic manipulations in mice show that dopamine signals from the ventral tegmental area to the lateral entorhinal cortex have a key role in cue–reward associative learning.

Leidal et al. show that the LC3-conjugation pathway, which is part of the autophagy machinery, controls extracellular vesicle cargo loading and secretion of RNA-binding proteins.

The quark structure of the f₀(980) hadron is still unknown after 50 years of its discovery. Here, the CMS Collaboration reports a measurement of the elliptic flow of the f₀(980) state in proton-lead collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV, providing strong evidence that the state is an ordinary meson.

Magnetic reconnection is a fundamental energy release mechanism in space and laboratory plasmas. Here, the authors show persistent magnetic null-point reconnection in the solar corona at a scale of about 390 km.

With the generation of large pan-cancer whole-exome and whole-genome sequencing projects, a question remains about how comparable these datasets are. Here, using The Cancer Genome Atlas samples analysed as part of the Pan-Cancer Analysis of Whole Genomes project, the authors explore the concordance of mutations called by whole exome sequencing and whole genome sequencing techniques.

Sr_1−yMn_1−zSb₂ (y, z < 0.1) is reported to be a magnetic topological semimetal exhibiting nearly massless relativistic fermions.

Graphene on boron nitride gives rise to a moiré superlattice displaying the Hofstadter butterfly: a fractal dependence of energy bands on external magnetic fields. Now, by means of capacitance spectroscopy, further aspects of this system are revealed—most notably, suppression of quantum Hall antiferromagnetism at particular commensurate magnetic fluxes.

An understanding of the molecular mechanisms promoting the generation of immunoregulatory and tumour-promoting monocytes and macrophages is key to breaking the cycle of tumour myelopoiesis and developing more effective myeloid-targeting therapies.

The evolution of the quantum Hall state from bulk spectrum to edge state remains obscure. Here, Patlatiuk and Scheller et al. observe magnetic compression against a hard edge followed by motion into the bulk and depopulation of the integer quantum Hall edge states, in agreement with the bulk-to-edge correspondence.

In situ measurements of the elemental abundances in the lunar southern high-latitude regions show that the local terrain is fairly uniform and mostly composed of ferroan anorthosite, a product of lunar magma ocean crystallization.

The spin helicity in helimagnets may be exploited in magnetic memory applications if electrically controllable and detectable. Here, helicity manipulation driven by an electric current and detection by second harmonic resistivity measurements in an itinerant helimagnet MnP is demonstrated.

Spin–orbit coupling in graphene is small, which makes controlling spin currents in this otherwise useful spintronic material difficult. Avsar et al.now demonstrate that combining graphene with few-layer tungsten disulphide increases its spin–orbit coupling by three orders of magnitude

Here the authors develop a dispersive Fourier transform (DFT) based LIDAR method utilizing phase-locked Vernier dual soliton laser combs and demonstrate improved precision in the measurements.

Polygenic scores for body mass index and obesity constructed using data from 5 million people with different ancestries were associated with distinct weight gain trajectories from early childhood to adulthood.

The Einstein Probe has discovered a fast X-ray transient, EP240414a, associated with a broad-lined type Ic supernova. Its unusually soft spectrum and weak jet add to the diversity of stellar deaths and suggest a previously unknown Wolf–Rayet star explosion mechanism.

Pathology-oriented multiplexing (PathoPlex) represents a framework for widespread access to multiplexed imaging and computational image analysis of clinical specimens at a relatively high throughput and subcellular resolution.

In this Perspective, members of the Aging Biomarker Consortium outline the X-Age Project, an Aging Biomarker Consortium plan for building standardized aging clocks in China. The authors discuss the project roadmap and its aims of decoding aging heterogeneity, detecting accelerated aging early and evaluating geroprotective interventions.

Oxide heterostructures are attractive for their tuneable properties such as magnetism. Here, the authors find that SrTiO₃/SmTiO₃heterostructures with very high sheet carrier densities show quantum critical behaviour, sensitive also to variations in layer thickness.

Recent advancements in the sample quality of infinite-layer nickelates have made systematic comparisons with cuprates increasingly relevant. Hsu et al. report anomalous electronic transport in high-crystallinity (Nd,Sr)NiO₂ at large magnetic fields, map out the transport phase diagram, and discuss similarities and differences with cuprates.

A subset of pediatric gliomas harbour alterations in fibroblast growth factor receptor (FGFR)-family proteins. Here, the authors characterise the genomic landscape of 11,635 gliomas across ages and use isogenic model systems to explore the underlying biology of FGFR1-altered gliomas and potential therapeutic vulnerabilities.

Real-time lab analysis is key to support clinical research during space missions. Here, the authors show scant test samples can be measured in microgravity using a miniature cytometery-based analyzer, the rHEALTH ONE with specific spaceflight modifications.

Electron correlation normally makes electrons less mobile, but it is still not clear when correlation becomes very strong in Dirac semimetals. Here, Fujioka et al. report a very high electron mobility exceeding 60,000 cm²V⁻¹s⁻¹ in correlated Dirac semimetal of perovskite CaIrO3, due to the enhanced electron correlation nearby the Mott transition.

The authors present SVclone, a computational method for inferring the cancer cell fraction of structural variants from whole-genome sequencing data.

Analysis of cancer genome sequencing data has enabled the discovery of driver mutations. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium the authors present DriverPower, a software package that identifies coding and non-coding driver mutations within cancer whole genomes via consideration of mutational burden and functional impact evidence.

A magneto-transport study of twisted bilayer graphene near the magic angle further reveals its rich physics.

By controlling the flow or composition of liquids, optofluidics provides numerous possibilities for devices, and so has great potential for transformation optics. Here, a multi-mode optofluidic waveguide is presented, which manipulates light to produce controllable chirped focussing and interference.

The study revealed how nitrogen fertilization affects fast and slow turnover pools of soil organic carbon differently. The authors found labile particulate organic carbon increased if SOC was below 1.5%, while stable mineral associated organic carbon increased above this critical threshold.

Understanding “strange metal" behavior in high-temperature superconductors remains an open problem. Here the authors report a correlation between linear-in-magnetic-field magnetoresistance and linear-in-temperature resistivity in several hole-doped cuprate families and discuss its possible implications for superconductivity.

There’s an emerging body of evidence to show how biological sex impacts cancer incidence, treatment and underlying biology. Here, using a large pan-cancer dataset, the authors further highlight how sex differences shape the cancer genome.

Deep-sea hydrothermal plumes support an array of microbial metabolisms, but the fate of organic carbon in these systems is unknown. Here, the authors used metabolic rate assays and metagenomic data to show that heterotrophic bacteria contribute significantly to carbon cycling in the deep sea.

Integrative analyses of transcriptome and whole-genome sequencing data for 1,188 tumours across 27 types of cancer are used to provide a comprehensive catalogue of RNA-level alterations in cancer.

Whole-genome sequencing data for 2,778 cancer samples from 2,658 unique donors across 38 cancer types is used to reconstruct the evolutionary history of cancer, revealing that driver mutations can precede diagnosis by several years to decades.

Liu et al. developed a platform to identify transcription factors (TFs) that turn stem cells into desired cell types. They discovered six key TFs that produce microglia efficiently, enhancing cell differentiation methods.

Joint profiling of chromatin and splicing in the brain uncovers shared and distinct patterns.

The flagship paper of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium describes the generation of the integrative analyses of 2,658 cancer whole genomes and their matching normal tissues across 38 tumour types, the structures for international data sharing and standardized analyses, and the main scientific findings from across the consortium studies.

The LHCb experiment at CERN has observed significant asymmetries between the decay rates of the beauty baryon and its CP-conjugated antibaryon, thus demonstrating CP violation in baryon decays.