Abstract
Quantum effects in chemical reactions are most pronounced at ultracold temperatures, where only a few partial waves contribute. While interference among many partial waves is theoretically expected to persist at higher temperatures, direct evidence for such quantum effects in reactive processes has been lacking. Here, we report signatures of quantum interference suppressing a chemical reaction in the multi-partial-wave regime: resonant charge exchange between a single 87Rb+ ion and its parent atom 87Rb. Using quantum-logic detection on a single atom-ion pair and a calibrated in-situ measurement of Langevin collision probabilities, we benchmark the thermally averaged reaction rate against both classical and quantum predictions. We find that the reaction rate is suppressed by over an order of magnitude relative to the classical expectation, despite occurring in the millikelvin temperature regime (more than three orders of magnitude above the s-wave threshold), where more than a dozen partial waves contribute. These results suggest quantum interference as a key mechanism in chemical reactivity beyond the ultracold limit and offer a platform for probing coherent quantum effects in atom-ion reactions where ab initio methods remain intractable.
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Acknowledgements
This work was supported by the Israeli Science Foundation and the Goldring Family Foundation. We thank Marko Cetina, Maks Walewski, Mathew Frye, and Michał Tomza for fruitful discussions. O.K. acknowledges support from the U.S. Department of Energy, Office of Science, National Quantum Information Science Research Centers, Quantum Systems Accelerator.
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O.K., M.P., and N.A. contributed to the development of the experimental setup. O.K. performed the experiments. M.L. carried out the numerical simulations and theoretical analysis. O.K. analyzed the experimental data. R.O. supervised the research and secured funding. All authors contributed to the conception, design, interpretation, and writing of the manuscript.
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Katz, O., Pinkas, M., Akerman, N. et al. Quantum suppression of cold reactions far from the s-wave energy limit. Nat Commun (2026). https://doi.org/10.1038/s41467-025-67915-x
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DOI: https://doi.org/10.1038/s41467-025-67915-x
