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Natural products biosynthesis

At the roots of resistance

The discovery of seven soybean genes completes the biosynthetic pathway to major glyceollins, granting access to heterologous production and exploration of their antimicrobial potential.

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Fig. 1: Resolving the final steps of the glyceollin biosynthetic pathway for complete pathway reconstitution.

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Correspondence to Mehran Dastmalchi.

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Raytek, L.M., Dastmalchi, M. At the roots of resistance. Nat Chem Biol 21, 1473–1475 (2025). https://doi.org/10.1038/s41589-025-01937-w

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