Extended Data Fig. 5: Supplementary transcriptome data. | Nature Aging

Extended Data Fig. 5: Supplementary transcriptome data.

From: Polyamine metabolite spermidine rejuvenates oocyte quality by enhancing mitophagy during female reproductive aging

Extended Data Fig. 5

a, The number of DEGs that were upregulated (red) and downregulated (blue) in aged oocytes compared to young controls. b, The number of DEGs that were upregulated (red) and downregulated (blue) in Spd+aged oocytes compared to aged ones. c, Venn diagram displayed the number of overlapping DEGs between aged compared to young group and Spd+aged compared to aged group. d, Volcano plot showed DEGs (upregulated, red; downregulated, blue) in Spd+aged oocytes compared to young ones. Some highly different DEGs were listed. e, KEGG interaction network of DEGs in the autophagy pathway. f, KEGG interaction network of DEGs in the mitophagy pathway.

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